Title:
VACCINE ADJUVANT, VACCINE COMPOSITION, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/066288
Kind Code:
A1
Abstract:
Provided is a vaccine adjuvant, comprising a ginseng acidic polysaccharide (GAPS) adjuvant and an aluminum salt adjuvant. The mixture of the ginseng acidic polysaccharide (GAPS) and the aluminum salt can significantly improve the titer of a specific antibody (or a neutralizing antibody) after antigen immunization, can effectively enhance the immune response level of an organism to a vaccine, and has an activity significantly higher than that of a single aluminum salt adjuvant.
Inventors:
ZHAI JIANXIU (CN)
YIN JUN (CN)
LIAO HUI (CN)
YIN JUN (CN)
LIAO HUI (CN)
Application Number:
PCT/CN2023/087304
Publication Date:
April 04, 2024
Filing Date:
April 10, 2023
Export Citation:
Assignee:
UNIV SHENYANG PHARMACEUTICAL (CN)
International Classes:
A61K39/39; A61K39/00
Domestic Patent References:
| WO2021186456A1 | 2021-09-23 |
Foreign References:
| CN115501333A | 2022-12-23 | |||
| CN107157933A | 2017-09-15 | |||
| CN101747446A | 2010-06-23 | |||
| CN102133396A | 2011-07-27 | |||
| CN102827256A | 2012-12-19 | |||
| CN101862346A | 2010-10-20 |
Other References:
XIAO-MIN WU, ZHAO DAN; ZHU YAN-PING; WANG YAN-HONG;JILIN: "Advance in pharmacological and clinical research of ginseng Polysaccharide", GINSENG RESEARCH, vol. 2016, no. 5, 7 October 2016 (2016-10-07), pages 40 - 46, XP093142171, DOI: 10.19403/j.cnki.1671-1521.2016.05.011
Attorney, Agent or Firm:
BEIJING CAI HE LAW FIRM (CN)
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