TM2 COMPOUND CRYSTAL FORM, PREPARATION METHOD THEREFOR, AND USE THEREOF

Title:

TM2 COMPOUND CRYSTAL FORM, PREPARATION METHOD THEREFOR, AND USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2024/094110

Kind Code:

A1

Abstract:

The present invention relates to a TM2 compound crystal form, a preparation method therefor, and a use thereof. The TM2 compound crystal form A is obtained by performing recrystallisation with at least one of ethyl acetate, absolute ethanol, isopropanol, methanol, and acetonitrile. The prepared TM2 crystal form A has large particle size, easier solid-liquid separation during filtering, short drying time, and high stability, and presents as a single crystal form, achieving higher purity and better stability.

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Inventors:

TAO XIUMEI (CN)
CHEN CHENGJUN (CN)
ZHANG YUJIE (CN)
HE MINGRUI (CN)
MA LIDUAN (CN)
ZHANG XIAOBIN (CN)

Application Number:

PCT/CN2023/129288

Publication Date:

May 10, 2024

Filing Date:

November 02, 2023

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Assignee:

NKD PHARM CO LTD (CN)

International Classes:

C07D305/14; A61K31/337; A61P35/00

Attorney, Agent or Firm:

CN-KNOWHOW INTELLECTUAL PROPERTY AGENT LIMITED (21th Floor West Tower, Ginza Harmonious Plaza, No.68 Wanfeng R, Fengtai District Beijing 1, CN)

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