Title:
TANSHINONE COMPOUND AND USE THEREOF FOR TREATING HEMANGIOMA
Document Type and Number:
WIPO Patent Application WO/2019/052477
Kind Code:
A1
Abstract:
Provided is the use of a class of tanshinone compounds for treating hemangioma; in particular, provided is the use of a class of compounds as shown in formula I below or a pharmaceutically acceptable salt thereof. The tanshinone compounds have a hemangioma cell inhibitory activity and can be used for preparing a pharmaceutical composition for treating hemangioma.
Inventors:
WU YEMING (CN)
YE YANG (CN)
WU ZHIXIANG (CN)
YAO SHENG (CN)
CAI YIHONG (CN)
TAN MINJIA (CN)
YE YANG (CN)
WU ZHIXIANG (CN)
YAO SHENG (CN)
CAI YIHONG (CN)
TAN MINJIA (CN)
Application Number:
PCT/CN2018/105278
Publication Date:
March 21, 2019
Filing Date:
September 12, 2018
Export Citation:
Assignee:
XINHUA HOSPITAL AFFILIATED TO SHANGHAI JIAOTONG UNIV SCHOOL OF MEDICINE (CN)
SHANGHAI INST MATERIA MEDICA CAS (CN)
SHANGHAI INST MATERIA MEDICA CAS (CN)
International Classes:
C07J73/00; A61K31/122; A61K31/343; A61P35/00; C07C50/16
Foreign References:
| CN101412744A | 2009-04-22 | |||
| CN101732294A | 2010-06-16 | |||
| TW201021808A | 2010-06-16 | |||
| CN103845314A | 2014-06-11 |
Other References:
TSAI, MINGYEN ET AL.: "Anti-Angiogenic Effect of Tanshinone Iia Involves Inhibition of Matrix Invasion and Modification of Mmp-2/Timp-2 Secretion in Vascular Endothelial Cells", CANCER LETTERS, vol. 310, no. 2, 28 November 2011 (2011-11-28), XP028266576, ISSN: 0304-3835, DOI: doi:10.1016/j.canlet.2011.06.031
Attorney, Agent or Firm:
XU AND PARTNERS, LLC. (CN)
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