Title:
SINGLE-POLYMER PARTICLES, ACTIVE MOLECULAR COMPLEX, METHOD FOR PRODUCING SINGLE-POLYMER PARTICLES, METHOD FOR MEASURING TUMOR SIZE, METHOD FOR MEASURING FINE STRUCTURE WITHIN TUMOR, METHOD FOR IMAGING BIOLOGICAL TISSUE, DRUG DELIVERY SYSTEM, AND CONTRAST AGENT KIT
Document Type and Number:
WIPO Patent Application WO/2023/199723
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing single-polymer particles having a more precisely controlled hydrodynamic diameter, an active molecular complex, a method for producing single-polymer particles, and a method for imaging biological tissue. In order to solve the aforementioned problem, provided are single-polymer particles characterized in that each particle is formed from a single polymer and in that the molecular weight distribution Mw/Mn is 1.5 or less. This makes it possible to obtain particles having a more precisely controlled hydrodynamic diameter. The single polymer is preferably a structure composed of a single hydrophilic polymer A or a structure in which a side chain of one or more hydrophilic polymers B is bonded to a main chain composed of a single hydrophilic polymer A.
Inventors:
OSADA KENSUKE (JP)
RIKIYAMA KAZUAKI (JP)
SUMIYOSHI AKIRA (JP)
AOKI ICHIO (JP)
MIYATA KANJIRO (JP)
NAITO MITSURU (JP)
WATANUKI YUSUKE (JP)
RIKIYAMA KAZUAKI (JP)
SUMIYOSHI AKIRA (JP)
AOKI ICHIO (JP)
MIYATA KANJIRO (JP)
NAITO MITSURU (JP)
WATANUKI YUSUKE (JP)
Application Number:
PCT/JP2023/011719
Publication Date:
October 19, 2023
Filing Date:
March 24, 2023
Export Citation:
Assignee:
NATIONAL INSTITUTES FOR QUANTUM SCIENCE AND TECH (JP)
International Classes:
C08G81/00; A61K9/08; A61K47/34; A61K47/56; A61K47/62; A61K49/14
Domestic Patent References:
| WO2016021407A1 | 2016-02-11 | |||
| WO2018207864A1 | 2018-11-15 | |||
| WO2016178431A1 | 2016-11-10 |
Foreign References:
| US20130071482A1 | 2013-03-21 | |||
| JP2021020872A | 2021-02-18 |
Attorney, Agent or Firm:
BENRISHIHOJIN YUKON (JP)
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