Title:
QUATERNARY AMMONIUM STEROID COMPOUND, PREPARATION METHOD THEREFOR, PREPARATION AND USE
Document Type and Number:
WIPO Patent Application WO/2022/078483
Kind Code:
A1
Abstract:
A quaternary ammonium steroid compound represented by formula I, or an addition salt or a solvate of the quaternary ammonium steroid compound: wherein R 1 is H or CH 3CO; R 2 is CH 3 or -CH 2CH＝CH 2, and t is equal to 2 or 3; X is Cl, Br or CH 3COO; Y is Cl, Br or CH 3COO; the values of m and n are both ≥0, and m+n＝1 or 2; and the condition is: when any one of X and Y is Br, m+n＝2. The invention further relates to a preparation method for the compound, a preparation and the use.
Inventors:
LI QINGENG (CN)
CHEN JIE (CN)
LIAO JIAN (CN)
SHEN YI (CN)
DONG XIAOHU (CN)
TAN BO (CN)
CHEN JIE (CN)
LIAO JIAN (CN)
SHEN YI (CN)
DONG XIAOHU (CN)
TAN BO (CN)
Application Number:
PCT/CN2021/123999
Publication Date:
April 21, 2022
Filing Date:
October 15, 2021
Export Citation:
Assignee:
JIANGSU NHWALUOKANG PHARMACEUTICAL RES AND DEVELOPMENT CO LTD (CN)
International Classes:
C07J43/00; A61K9/19; A61K31/58; A61P21/02
Foreign References:
| US4297351A | 1981-10-27 | |||
| CN102481195A | 2012-05-30 | |||
| CN104519872A | 2015-04-15 | |||
| CN1864667A | 2006-11-22 | |||
| CN103520121A | 2014-01-22 |
Attorney, Agent or Firm:
NTD UNIVATION INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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