Title:
PYRIDAZOPYRIDONE COMPOUNDS, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/143147
Kind Code:
A1
Abstract:
Provided in the present invention are pyridazopyridone compounds, a pharmaceutical composition thereof, and the use thereof. Specifically, the compounds have structures as shown in formula (I). The compounds can interfere with the interaction between SOS1 protein and RAS protein, and are thereby expected to be used for preparing drugs for treating diseases such as RAS mutated tumors.
Inventors:
CHEN XUXING (CN)
CHEN YANHONG (CN)
CHEN YANHONG (CN)
Application Number:
PCT/CN2023/072192
Publication Date:
August 03, 2023
Filing Date:
January 13, 2023
Export Citation:
Assignee:
SHANGHAI EUREGEN BIOPHARMA CO LTD (CN)
International Classes:
C07D471/04; A61K31/5025; A61P35/00; C07D237/00; C07D403/04
Domestic Patent References:
| WO2021127429A1 | 2021-06-24 | |||
| WO2010025201A1 | 2010-03-04 |
Foreign References:
| CN111372932A | 2020-07-03 | |||
| CN113200981A | 2021-08-03 | |||
| CN110167928A | 2019-08-23 | |||
| CN110563722A | 2019-12-13 |
Attorney, Agent or Firm:
XU & PARTNERS, LLC. (CN)
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