Title:
PROTEIN COMPOSITION FOR REPAIRING HAIR FOLLICLE, AND PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/143528
Kind Code:
A1
Abstract:
Disclosed is a protein composition for repairing hair follicles, wherein the preparation method therefor comprises the following steps: adding any one of or a combination of 20 U/mL-35 U/mL of a nuclease or benzonase nuclease to a cell protein extract, performing enzymatic hydrolysis under the condition of 37°C±1°C for 15 min-40 min, and separating and purifying the prepared enzymatic hydrolysate. The obtained cell protein extract and cell protein composition have the effects of repairing damaged hair follicle cells, efficiently repairing damaged hair follicles and significantly improving the activity of hair follicles, and have the advantages of a high purity, a good stability, being safe and effective, and effectively solving the problems of living cells needing to be refrigerated, the activity thereof being limited by cell viability duration, etc.
Inventors:
WANG YU (CN)
GAO WENYONG (CN)
CHEN LIN (CN)
LI JIANJUN (CN)
GAO WENYONG (CN)
CHEN LIN (CN)
LI JIANJUN (CN)
Application Number:
PCT/CN2023/073590
Publication Date:
August 03, 2023
Filing Date:
January 28, 2023
Export Citation:
Assignee:
BEIJING DARWIN BIOTECH CO LTD (CN)
International Classes:
C12P21/00; A61K35/28; A61P17/14; A61Q7/00; C12N5/071; C12N5/0775
Foreign References:
| CN111840330A | 2020-10-30 | |||
| CN113750116A | 2021-12-07 | |||
| CN110269833A | 2019-09-24 | |||
| CN113893266A | 2022-01-07 |
Other References:
SOMBATSRI AONNICHA; THUMMANANT YUTTHAPONG; SRIBUHOM THURDPONG; BOONMAK JAURSUP; YOUNGME SUJITTRA; PHUSRISOM SUPHANTHIP; KUKONGVIRI: "New limonophyllines A-C from the stem ofAtalantia monophyllaand cytotoxicity against cholangiocarcinoma and HepG2 cell lines", ARCHIVES OF PHARMACAL RESEARCH, NATL. FISHERIES UNIVERSITY , PUSAN, KR, vol. 41, no. 4, 15 March 2018 (2018-03-15), KR , pages 431 - 437, XP036488625, ISSN: 0253-6269, DOI: 10.1007/s12272-018-1021-7
Attorney, Agent or Firm:
BEIJING ZHIDA TONGCHENG INTELLECTUAL PROPERTY AGENCY (CN)
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