Title:
POROUS PARTICLES, METHOD FOR PRODUCING SAME, AND FILLER FOR CHROMATOGRAPHY USING SAME
Document Type and Number:
WIPO Patent Application WO/2023/032346
Kind Code:
A1
Abstract:
The present invention provides: porous particles each having a controlled three-dimensional network skeleton and communicating pores that are formed of voids of the skeleton, the communicating pores penetrating each porous particle from the particle surface to the inside; a method for producing the porous particles; and a filler for chromatography, the filler using the porous particles. The porous particles are mainly composed of cellulose acetate or cellulose, and are characterized in that: each of the porous particles is spherical and has a three-dimensional network skeleton and a communicating pore structure that is composed of voids of the three-dimensional network skeleton; the communicating pores penetrate each porous particle from the particle surface to the inside; and if a column having an inner diameter of 0.78 cm and a length of 30 cm is filled with the porous particles, the retention time of a dextran having a molecular weight of 2,000,000 is 20 minutes or more at a flow rate of 0.4 ml/min.
Inventors:
KADOI KENJI (JP)
IWAMOTO ERI (JP)
NAKAMA TSUYOSHI (JP)
IWAMOTO ERI (JP)
NAKAMA TSUYOSHI (JP)
Application Number:
PCT/JP2022/017899
Publication Date:
March 09, 2023
Filing Date:
April 15, 2022
Export Citation:
Assignee:
JNC CORP (JP)
International Classes:
C08J3/16; B01D15/08; B01J20/24; B01J20/26; B01J20/28; B01J20/281; B01J20/285; B01J20/30; C08B3/06; C08B15/08
Domestic Patent References:
| WO2016063702A1 | 2016-04-28 | |||
| WO2016013568A1 | 2016-01-28 | |||
| WO2017026424A1 | 2017-02-16 | |||
| WO2015029790A1 | 2015-03-05 |
Foreign References:
| JP2019048987A | 2019-03-28 | |||
| JP2014224223A | 2014-12-04 | |||
| JP2021021045A | 2021-02-18 | |||
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| JPS5624429A | 1981-03-09 | |||
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Other References:
P DEPHILLIPSA M LENHOFF, JCHROMATOGR A., vol. 883, 2000, pages 39
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