Title:
POLYPEPTIDE, NUCLEIC ACID, MOLDED BODY, COMPOSITION AND METHOD FOR PRODUCING SAME, AND PROPERTY IMPROVING AGENT
Document Type and Number:
WIPO Patent Application WO/2021/235417
Kind Code:
A1
Abstract:
[Problem] To provide a composition and a molded body having improved mechanical properties such as stress and elongation. [Solution] A polypeptide that comprises an amino acid sequence having 70% or higher identity to the amino acid sequence consisting of from the 21st to 252nd amino acids in SEQ ID NO: 1.
Inventors:
NUMATA KEIJI (JP)
NAKAMURA HIROYUKI (JP)
ARAKAWA KAZUHARU (JP)
KONO NOBUAKI (JP)
NAKAMURA HIROYUKI (JP)
ARAKAWA KAZUHARU (JP)
KONO NOBUAKI (JP)
Application Number:
PCT/JP2021/018695
Publication Date:
November 25, 2021
Filing Date:
May 18, 2021
Export Citation:
Assignee:
SPIBER INC (JP)
UNIV KEIO (JP)
NUMATA KEIJI (JP)
UNIV KEIO (JP)
NUMATA KEIJI (JP)
International Classes:
C12N15/11; C07K14/435; C08L89/00; C12N15/12; D01F4/00; D01F4/02
Other References:
WHAITE, A.D. ET AL.: "Major ampullate silk gland transcriptomes and fibre proteomes of the golden orbweavers, Nephila plumipes and Nephila pilipes (Araneae: Nephilidae", PLOS ONE, vol. 13, no. 10, 2018, pages 1 - 22, XP055875154
CLARKE THOMAS H., GARB JESSICA E, HAYASHI CHERYL Y, HANEY ROBERT A, LANCASTER ALEXANDER K, CORBETT SUSAN, AYOUB NADIA A: "Multi-tissue transcriptomics of the black widow spider reveals expansions, co-options, and functional processes of the silk gland gene toolkit", BMC GENOMICS, vol. 15, no. 365, 2014, pages 1 - 17, XP021187307
CHAW, R.C. ET AL.: "Proteomic Evidence for Components of Spider Silk Synthesis from Black Widow Silk Glands and Fibers", J. PROTEOME RES., vol. 14, no. 10, 2015, pages 4223 - 4231, XP055875177
KONO, NOBUAKI ET AL.: "Orb-weaving spider Araneus ventricosus genome elucidates the spidroin gene catalogue", SCIENTIFIC REPORTS, vol. 9, no. 8380, 2019, pages 1 - 13, XP055875203
GARB JESSICA E., HANEY ROBERT A., SCHWAGER EVELYN E., GREGORIČ MATJAŽ, KUNTNER MATJAŽ, AGNARSSON INGI, BLACKLEDGE TODD A.: "The transcriptome of Darwin' s bark spider silk glands predicts proteins contributing to dragline silk toughness", COMMUNICATIONS BIOLOGY, vol. 2, no. 275, 2019, pages 1 - 8, XP055875220
CLARKE THOMAS H., GARB JESSICA E, HAYASHI CHERYL Y, HANEY ROBERT A, LANCASTER ALEXANDER K, CORBETT SUSAN, AYOUB NADIA A: "Multi-tissue transcriptomics of the black widow spider reveals expansions, co-options, and functional processes of the silk gland gene toolkit", BMC GENOMICS, vol. 15, no. 365, 2014, pages 1 - 17, XP021187307
CHAW, R.C. ET AL.: "Proteomic Evidence for Components of Spider Silk Synthesis from Black Widow Silk Glands and Fibers", J. PROTEOME RES., vol. 14, no. 10, 2015, pages 4223 - 4231, XP055875177
KONO, NOBUAKI ET AL.: "Orb-weaving spider Araneus ventricosus genome elucidates the spidroin gene catalogue", SCIENTIFIC REPORTS, vol. 9, no. 8380, 2019, pages 1 - 13, XP055875203
GARB JESSICA E., HANEY ROBERT A., SCHWAGER EVELYN E., GREGORIČ MATJAŽ, KUNTNER MATJAŽ, AGNARSSON INGI, BLACKLEDGE TODD A.: "The transcriptome of Darwin' s bark spider silk glands predicts proteins contributing to dragline silk toughness", COMMUNICATIONS BIOLOGY, vol. 2, no. 275, 2019, pages 1 - 8, XP055875220
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