Title:
PICHIA PASTORIS FERMENTATION LYSATE FILTRATE, PREPARATION METHOD THEREFOR, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/027798
Kind Code:
A1
Abstract:
The present invention provides a Pichia pastoris fermentation lysate filtrate, a preparation method therefor, and use thereof, and belongs to the technical field of cosmetic raw materials. Provided is a fermentation lysate filtrate prepared by using Pichia pastoris expressing recombinant collagen and performing fermentation. The fermentation lysate filtrate comprises total protein, recombinant collagen, polysaccharides, amino acids, and various vitamins. Pichia pastoris fermentation bacteria expressing recombinant human collagen are used for preparing cosmetic raw materials for the first time, so that the waste treatment pressure caused by yeast fermentation bacteria is reduced, and waste is turned into wealth. The preparation method for the Pichia pastoris fermentation lysate filtrate is a whole-process online and automatic preparation process, and the preparation process is rapid and efficient. Meanwhile, the breeding of harmful bacteria can be effectively controlled during the whole preparation process flow. The lysate filtrate has the effects of soothing skin, enhancing a skin micro-ecological barrier, controlling oil, screening sunlight, and the like at the same time, thereby widening the application range thereof in preparing cosmetics.
Inventors:
LI JIAJIA (CN)
JI BAIHUI (CN)
QIAN SONG (CN)
CAO KAIJIE (CN)
CHEN JUYIN (CN)
SHI YEFEI (CN)
JI BAIHUI (CN)
QIAN SONG (CN)
CAO KAIJIE (CN)
CHEN JUYIN (CN)
SHI YEFEI (CN)
Application Number:
PCT/CN2023/111026
Publication Date:
February 08, 2024
Filing Date:
August 03, 2023
Export Citation:
Assignee:
JIANGSU TRAUTEC MEDICAL TECH CO LTD (CN)
International Classes:
C12P1/02; A61K8/9728; A61Q19/00; C12P21/02; C12R1/84
Foreign References:
| CN115074393A | 2022-09-20 | |||
| CN116509764A | 2023-08-01 | |||
| CN110934766A | 2020-03-31 | |||
| CN113481244A | 2021-10-08 | |||
| KR20220049982A | 2022-04-22 | |||
| US20190241645A1 | 2019-08-08 | |||
| JP2019085331A | 2019-06-06 |
Other References:
ANONYMOUS: "The Role of Pichia Pastoris Fermentation Lysate Filtrate in Cosmetics", KEAI, 7 October 2021 (2021-10-07), XP093135154, Retrieved from the Internet [retrieved on 20240227]
Attorney, Agent or Firm:
NANJING IPZHI INTELLECTUAL PROPERTYAGENCY CO..LTD (CN)
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