Title:
PHOTO-CROSSLINKED HYALURONIC ACID BIO-INK FOR BIO-PRINTING, METHOD FOR PREPARING SAME, AND BIOLOGICAL STRUCTURE CAPABLE OF CONTROLLING PHYSICAL PROPERTIES USING SAME
Document Type and Number:
WIPO Patent Application WO/2022/119145
Kind Code:
A1
Abstract:
The present invention relates to a bio-ink composition for bio-printing comprising a polymer into which methacrylate is introduced, a crosslinking agent having 1-10 acrylate functional groups, and a photoinitiator; a method for preparing same; and a printing biostructure for controlling physical properties using same. The bio-ink composition for bio-printing prepared according to the present invention can be implanted in vivo and has a very high degree of biocompatibility or cell viability. In addition, the bio-ink composition of the present invention can be effectively utilized for bio-printing because a bio-structure can be produced that is capable of controlling physical properties or in vivo application even when irradiated with light for a short period of time.
Inventors:
KIM MOON SUK (KR)
PARK JOON YEONG (KR)
PARK JOON YEONG (KR)
Application Number:
PCT/KR2021/015656
Publication Date:
June 09, 2022
Filing Date:
November 02, 2021
Export Citation:
Assignee:
UNIV AJOU IND ACADEMIC COOP FOUND (KR)
International Classes:
C09D11/14; C08F2/50; C08F251/00; C09D11/04
Foreign References:
| KR20190070922A | 2019-06-21 | |||
| KR20200123350A | 2020-10-29 | |||
| KR20180112436A | 2018-10-12 |
Other References:
KIM, NAHUI: "Fabrication and Characterization of Artificial Ear Cartilages Containing ECM Powders using Bioprinting", MASTER THESIS, 10 December 2019 (2019-12-10), Korea, pages 1 - 22, XP009537220
MA YUFEI, JI YUAN, ZHONG TIANYU, WAN WANTING, YANG QINGZHEN, LI ANG, ZHANG XIAOHUI, LIN MIN: "Bioprinting-Based PDLSC-ECM Screening for in Vivo Repair of Alveolar Bone Defect Using Cell-Laden, Injectable and Photocrosslinkable Hydrogels", ACS BIOMATERIALS SCIENCE & ENGINEERING, vol. 3, no. 12, 11 December 2017 (2017-12-11), pages 3534 - 3545, XP055937393, ISSN: 2373-9878, DOI: 10.1021/acsbiomaterials.7b00601
MA YUFEI, JI YUAN, ZHONG TIANYU, WAN WANTING, YANG QINGZHEN, LI ANG, ZHANG XIAOHUI, LIN MIN: "Bioprinting-Based PDLSC-ECM Screening for in Vivo Repair of Alveolar Bone Defect Using Cell-Laden, Injectable and Photocrosslinkable Hydrogels", ACS BIOMATERIALS SCIENCE & ENGINEERING, vol. 3, no. 12, 11 December 2017 (2017-12-11), pages 3534 - 3545, XP055937393, ISSN: 2373-9878, DOI: 10.1021/acsbiomaterials.7b00601
Attorney, Agent or Firm:
ERUUM & LEEON INTELLECTUAL PROPERTY LAW FIRM (KR)
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