Title:
PHENYLCREATINE, ITS USE AND METHOD FOR ITS PRODUCTION
Document Type and Number:
WIPO Patent Application WO/2018/135977
Kind Code:
A1
Abstract:
The invention relates to the field of pharmaceutical chemistry, namely to new biologically active substances and their use and to a method of production. In particular, the invention relates to a derivative of creatine - phenylcreatine, its use as a functional analogue of creatine, as well as a nootropic agent and for the prevention or treatment of arrhythmia and a method of its production.
Inventors:
DUKHOVLINOV ILYA VLADIMIROVICH (RU)
Application Number:
PCT/RU2018/050004
Publication Date:
July 26, 2018
Filing Date:
January 18, 2018
Export Citation:
Assignee:
DUKHOVLINOV ILYA VLADIMIROVICH (RU)
ALEKSEEV ALEKSEI VIKTOROVICH (RU)
ALEKSEEV ALEKSEI VIKTOROVICH (RU)
International Classes:
C07C279/14; A61K31/155; A61P9/06; A61P25/28; C07C277/08
Foreign References:
| RU2132158C1 | 1999-06-27 |
Other References:
ROWLEY GERALD L. ET AL.: "On the Specificity of Creatine Kinase. New Glycocyamines and Glycocyamine Analogs Related to Creatine", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 93, no. 21, 20 October 1971 (1971-10-20), pages 5542 - 5551, XP055196662
DIETRICH ROBERT F. ET AL.: "Carbon-13 Nuclear Magnetic Resonance Studies of Creatine, Creatinine and some of their Analogs", ORGANIC MAGNETIC RESONANCE, vol. 13, no. 2, February 1980 (1980-02-01), pages 79 - 88, XP055505356
RAE CAROLINE ET AL.: "Oral creatine monohydrate supplementation improves brain performance: a double-blind, placebo-controlled, cross-over trial", PROCEEDINGS OF THE ROYAL SOCIETY LONDON B, vol. 270, no. 1529, 13 August 2003 (2003-08-13), pages 2147 - 2150, XP002680303
See also references of EP 3571186A4
DIETRICH ROBERT F. ET AL.: "Carbon-13 Nuclear Magnetic Resonance Studies of Creatine, Creatinine and some of their Analogs", ORGANIC MAGNETIC RESONANCE, vol. 13, no. 2, February 1980 (1980-02-01), pages 79 - 88, XP055505356
RAE CAROLINE ET AL.: "Oral creatine monohydrate supplementation improves brain performance: a double-blind, placebo-controlled, cross-over trial", PROCEEDINGS OF THE ROYAL SOCIETY LONDON B, vol. 270, no. 1529, 13 August 2003 (2003-08-13), pages 2147 - 2150, XP002680303
See also references of EP 3571186A4
Attorney, Agent or Firm:
FEDOROVA, EKATERINA Alekseevna (RU)
Download PDF: