Title:
PHARMACEUTICAL COMPOSITION CONTAINING ISOQUINOLINONE COMPOUND, AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2024/088364
Kind Code:
A1
Abstract:
The present disclosure relates to a pharmaceutical composition containing an isoquinolinone compound, and to a preparation method therefor. Specifically, the present disclosure provides a pharmaceutical composition containing 9,10-dimethoxy-2-[[2-(2-oxo-imidazoline-1-yl)-ethyl]-(2,4,6-trimethyl-phenyl)-amino]-6,7-dihydro-pyrimidinyl[6,1-a]-isoquinolin-4-one or a pharmaceutically acceptable salt thereof, and polysorbate 80. The pharmaceutical composition of the present disclosure exhibits good physical and chemical stability after being stored for several months.
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Inventors:
YANG YI (CN)
WANG HAIFENG (CN)
ZHOU YIN (CN)
WANG PINGPING (CN)
ZHOU XUEPING (CN)
WANG JINGWEN (CN)
WANG HAIFENG (CN)
ZHOU YIN (CN)
WANG PINGPING (CN)
ZHOU XUEPING (CN)
WANG JINGWEN (CN)
Application Number:
PCT/CN2023/126961
Publication Date:
May 02, 2024
Filing Date:
October 27, 2023
Export Citation:
Assignee:
JIANGSU HENGRUI PHARMACEUTICALS CO LTD (CN)
SHANGHAI HENGRUI PHARMACEUTICAL CO LTD (CN)
SHANGHAI HENGRUI PHARMACEUTICAL CO LTD (CN)
International Classes:
A61K31/519; A61K9/12; A61K9/19; A61K9/72; A61P1/04; A61P3/10; A61P11/06; A61P11/08; A61P13/12; A61P27/02
Domestic Patent References:
| WO2022228544A1 | 2022-11-03 | |||
| WO2023156794A1 | 2023-08-24 |
Foreign References:
| CN106794157A | 2017-05-31 | |||
| CN112912064A | 2021-06-04 | |||
| CN114286672A | 2022-04-05 |
Attorney, Agent or Firm:
GE CHENG & CO., LTD. (CN)
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