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Title:
PEPTIDE UREA DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING PEPTIDE UREA DERIVATIVE, AND APPLICATION OF PEPTIDE UREA DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2023/143612
Kind Code:
A1
Abstract:
Disclosed are a peptide urea derivative, a pharmaceutical composition containing the peptide urea derivative, and an application of the peptide urea derivative. The derivative is as represented by formula I, wherein R is a group containing radioactive metal ions or a group capable of optical imaging. The derivative can be used for preoperative imaging diagnosis and grading of PSMA positive prostate cancer, can also be used for treatment of various types and stages of prostate cancer, achieves the integration of diagnosis and treatment, and has a wide application prospect.

Inventors:
WANG ERIC YANJUN (CN)
YU HAIHUA (CN)
WANG KEVIN YU (CN)
HE JINQIU (CN)
Application Number:
PCT/CN2023/073860
Publication Date:
August 03, 2023
Filing Date:
January 30, 2023
Export Citation:
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Assignee:
BIVISION PHARMACEUTICALS INC (CN)
International Classes:
C07D257/02; A61K31/395; A61K51/04; A61P35/00; G01N33/60
Domestic Patent References:
WO2021013978A12021-01-28
WO2021245263A12021-12-09
Foreign References:
CN108541302A2018-09-14
CN105636924A2016-06-01
CN112770785A2021-05-07
CN111285918A2020-06-16
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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