Title:
OXIDE LAYER-CONTAINING ZIRCONIUM-NIOBIUM ALLOY TIBIAL PLATEAU PROSTHESIS HAVING BONE TRABECULA AND PREPARATION METHOD
Document Type and Number:
WIPO Patent Application WO/2022/088704
Kind Code:
A1
Abstract:
An oxide layer-containing zirconium-niobium alloy tibial plateau prosthesis having bone trabecula and a preparation method. The preparation method comprises: using zirconium-niobium alloy powder as a raw material, obtaining an intermediate product by means of 3D-printing integral forming, and then performing hot isostatic pressing, cryogenic treatment and surface oxidation to prepare the tibial plateau prosthesis comprising a near-plateau support bone trabecula layer (21) and a far-plateau support bone trabecula layer (20). The pore diameter and porosity of the near-plateau support bone trabecula layer (21) are uniformly set, and the pore diameter and porosity of the far-plateau support bone trabecula layer (20) are set according to different regions. A bone trabecula topological structure of the prepared tibial plateau prosthesis is in three-dimensional gradient distribution, the micro-strain of 64%-72% region of a finite element model is between the lowest effective strain threshold value and the hyper-physiological strain threshold value, the mechanical adaptability of the prosthesis is improved, and the prosthesis has excellent bone ingrowth performance; the formed oxide layer can integrally achieve excellent biocompatibility of an osseointegration interface and superhigh wear resistance and a low wear rate of a friction interface.
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Inventors:
LIU LU (CN)
CAO YU (CN)
LI JIANYU (CN)
ZHANG JINGKANG (CN)
ZHOU HONGXIU (CN)
CAO YU (CN)
LI JIANYU (CN)
ZHANG JINGKANG (CN)
ZHOU HONGXIU (CN)
Application Number:
PCT/CN2021/101287
Publication Date:
May 05, 2022
Filing Date:
June 21, 2021
Export Citation:
Assignee:
JUST HUAJIAN MEDICAL DEVICES TIANJIN CO LTD (CN)
International Classes:
A61F2/38; A61L27/04; C21D6/04; C22C16/00; C23C8/12
Foreign References:
| CN112315627A | 2021-02-05 | |||
| CN109938888A | 2019-06-28 | |||
| CN111826603A | 2020-10-27 | |||
| CN110742711A | 2020-02-04 | |||
| CN104087729A | 2014-10-08 | |||
| CN111270196A | 2020-06-12 | |||
| CN104818409A | 2015-08-05 | |||
| US20160305005A1 | 2016-10-20 | |||
| CN109938888A | 2019-06-28 |
Other References:
YANG DE-YU;WANG YUE-E;HUANG DONG-HAI;LÜ HONG-SHENG;YOU RUI-JIN: "Application of Oxinium Knee Prosthesis in Total Knee Arthroplasty", JOURNAL OF CLINICAL ORTHOPAEDICS, vol. 22, no. 4, 13 August 2019 (2019-08-13), pages 430 - 433, XP055926396, ISSN: 1008-0287, DOI: 10.3969/j.issn.1008-0287.2019.04.017
See also references of EP 4094729A4
See also references of EP 4094729A4
Attorney, Agent or Firm:
BEI & OCEAN (CN)
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