Title:
ONCOLYTIC VIRUS BOOSTS T CELL RESPONSE FOR EFFECTIVE TIL THERAPY
Document Type and Number:
WIPO Patent Application WO/2022/093944
Kind Code:
A3
Abstract:
Disclosed are and methods for expanding tumor infiltrating lymphocyte (TIL) populations and methods of the use of the expanded TIL population for treating cancer.
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Inventors:
BEG AMER (US)
CANTWELL MARK J (US)
CANTWELL MARK J (US)
Application Number:
PCT/US2021/056829
Publication Date:
July 21, 2022
Filing Date:
October 27, 2021
Export Citation:
Assignee:
H LEE MOFFITT CANCER CT & RES (US)
MEMGEN INC (US)
MEMGEN INC (US)
International Classes:
C12N15/86
Domestic Patent References:
| WO2019246111A1 | 2019-12-26 |
Foreign References:
| US20190177693A1 | 2019-06-13 |
Other References:
MATHILDE FEIST; ZHI ZHU; ENYONG DAI; CONGRONG MA; ZUQIANG LIU; ESTHER GIEHL; ROSHNI RAVINDRANATHAN; STACY J KOWALSKY; NATASA OBERM: "Oncolytic virus promotes tumor-reactive infiltrating lymphocytes for adoptive cell therapy", CANCER GENE THERAPY, 19 December 2019 (2019-12-19), pages 98 - 111, XP055742365, DOI: 10.1038/s41417-020-0189-4
Attorney, Agent or Firm:
LANIER, J. Gibson et al. (US)
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