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Title:
NUCLEIC ACID NANO VACCINE DERIVED FROM BACTERIAL OUTERMEMBRANE VESICLE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/142999
Kind Code:
A1
Abstract:
A nano vaccine used for delivering an mRNA antigen and derived from a bacterial outermembrane vesicle and the use thereof. Specifically provided is a technology for displaying nucleic acid on the outer surface of a vesicle.

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Inventors:
NIE GUANGJUN (CN)
ZHAO XIAO (CN)
LI YAO (CN)
Application Number:
PCT/CN2023/071288
Publication Date:
August 03, 2023
Filing Date:
January 09, 2023
Export Citation:
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Assignee:
NAT CT NANOSCIENCE & TECHNOLOGY CHINA (CN)
International Classes:
C12N15/88; A61K9/127; C07K17/00
Domestic Patent References:
WO2021095842A12021-05-20
WO2004060350A12004-07-22
WO2004090165A12004-10-21
Foreign References:
US20200208157A12020-07-02
US20200155703A12020-05-21
CN110229820A2019-09-13
Other References:
LI YAO, MA XIAOTU, YUE YALE, ZHANG KAIYUE, CHENG KEMAN, FENG QINGQING, MA NANA, LIANG JIE, ZHANG TIANJIAO, ZHANG LIZHUO, CHEN ZHIQ: "Rapid Surface Display of mRNA Antigens by Bacteria‐Derived Outer Membrane Vesicles for a Personalized Tumor Vaccine", ADVANCED MATERIALS, VCH PUBLISHERS, DE, vol. 34, no. 20, 1 May 2022 (2022-05-01), DE , XP093080791, ISSN: 0935-9648, DOI: 10.1002/adma.202109984
Attorney, Agent or Firm:
SHANGHAI DIANSHI PARTNERS, P.C. (CN)
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