Title:
NOVEL GLUCOSE DERIVATIVE AS SGLT-2 INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2018/155970
Kind Code:
A1
Abstract:
The present invention relates to a novel glucose derivative, and said novel compound is useful as an SGLT-2 inhibitor. In addition, the novel glucose derivative according to the present invention has a relatively higher melting point, lower hygroscopicity, and superior storage stability compared to dapagliflozin, which is a drug developed as an SGLT-2 inhibitor, and thus is very suitable for formulation.
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Inventors:
KWAK WOO-YOUNG (KR)
SUNG SI-YOUNG (KR)
KIM JAE-HAN (KR)
MIN JONG-PIL (KR)
ULLAPU PUNNA REDDY (KR)
MOK HUI-YEON (KR)
KIM EUN JUNG (KR)
LEE DAE-YOUNG (KR)
KIM KYEONG-MIN (KR)
KIM HYUN-JUNG (KR)
SUNG SI-YOUNG (KR)
KIM JAE-HAN (KR)
MIN JONG-PIL (KR)
ULLAPU PUNNA REDDY (KR)
MOK HUI-YEON (KR)
KIM EUN JUNG (KR)
LEE DAE-YOUNG (KR)
KIM KYEONG-MIN (KR)
KIM HYUN-JUNG (KR)
Application Number:
PCT/KR2018/002295
Publication Date:
August 30, 2018
Filing Date:
February 23, 2018
Export Citation:
Assignee:
DONG A ST CO LTD (KR)
International Classes:
C07H15/04; C07H7/04
Domestic Patent References:
| WO2016041470A1 | 2016-03-24 |
Foreign References:
| CN104109179A | 2014-10-22 | |||
| CN105541816A | 2016-05-04 | |||
| KR20120034747A | 2012-04-12 | |||
| KR20140022086A | 2014-02-21 |
Other References:
DESHPANDE, P. P. ET AL.: "A Practical Stereoselective Synthesis and Novel Cocrystallizations of an Amphiphatic SGLT-2 Inhibitor", ORG. PROCESS RES. DEV., vol. 16, no. 4, 2012, pages 577 - 585, XP055538726
Attorney, Agent or Firm:
ROH, Jae-Chull (KR)
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