MODIFIED RNA FOR PREPARING MRNA VACCINE AND THERAPEUTIC AGENT

Title:

MODIFIED RNA FOR PREPARING MRNA VACCINE AND THERAPEUTIC AGENT

Document Type and Number:

WIPO Patent Application WO/2024/014770

Kind Code:

A1

Abstract:

The present application relates to a modified RNA for preparing a mRNA vaccine and therapeutic agent, the modified RNA, according to one aspect, comprising a specific chemical modification and genetic modification and thus being capable of notably reducing the induction of the innate immune response caused by the administration of a RNA, and also exhibiting excellent protein expression or translation efficiency, thereby being usefully employable in the fields of therapeutic agents and vaccines.

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Inventors:

HONG SUN WOO (KR)
KIM KYEONG MI (KR)
KANG YOUNG GUE (KR)
LEE JAE JIN (KR)

Application Number:

PCT/KR2023/009440

Publication Date:

January 18, 2024

Filing Date:

July 04, 2023

Export Citation:

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Assignee:

MCUREX THERAPEUTICS INC (KR)

International Classes:

C12N15/11; A61K31/7115; C07H19/067; C12N15/63

Domestic Patent References:

WO2021213924A1	2021-10-28
WO2021154763A1	2021-08-05
WO2021156267A1	2021-08-12

Foreign References:

US20190255194A1	2019-08-22
KR20210038886A	2021-04-08

Attorney, Agent or Firm:

Y.P.LEE, MOCK & PARTNERS (KR)

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