Title:
MODIFIED MICROORGANISM OF GENUS CORYNEBACTERIUM PRODUCING L-GLUTAMIC ACID AND METHOD FOR PRODUCING L-GLUTAMIC ACID USING SAME
Document Type and Number:
WIPO Patent Application WO/2024/096218
Kind Code:
A1
Abstract:
The present invention relates to a modified microorganism of the genus Corynebacterium producing L-glutamic acid and a method for producing L-glutamic acid using same, more specifically to a novel variant of nicotinamide mononucleotide transporter involved in the L-glutamic acid biosynthesis pathway, polynucleotide, and transformant, and a method for producing L-glutamic acid using same. The nicotinamide mononucleotide transporter variant according to the present invention has substitution of one or more amino acids in the amino acid sequence constituting the nicotinamide mononucleotide transporter to result in altered enzyme activity, and thus allows a recombinant microorganism comprising the variant to efficiently produce L-glutamic acid.
Inventors:
LEE SUN HEE (KR)
KIM HYUN HO (KR)
KIM DONG HYUN (KR)
KIM HYUN SOOK (KR)
PARK JOON HYUN (KR)
KIM HYUN HO (KR)
KIM DONG HYUN (KR)
KIM HYUN SOOK (KR)
PARK JOON HYUN (KR)
Application Number:
PCT/KR2023/007163
Publication Date:
May 10, 2024
Filing Date:
May 25, 2023
Export Citation:
Assignee:
DAESANG CORP (KR)
International Classes:
C12N9/12; C07K14/34; C12N15/77; C12P13/14
Foreign References:
| KR100837844B1 | 2008-06-13 | |||
| JP2014036576A | 2014-02-27 | |||
| KR102257842B1 | 2021-05-28 | |||
| KR20110074521A | 2011-06-30 |
Other References:
DATABASE PROTEIN 18 October 2022 (2022-10-18), ANONYMOUS: "nicotinamide riboside transporter PnuC [Corynebacterium glutamicum]", XP093166446, Database accession no. WP_216312841.1
Attorney, Agent or Firm:
PARK, Hyuk (KR)
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