Title:
MODIFIED FIBROIN
Document Type and Number:
WIPO Patent Application WO/2021/015153
Kind Code:
A1
Abstract:
This invention relates to a modified fibroin which includes a domain sequence represented by formula 1, [(A)n
motif-REP]m, or formula 2, [(A)n
motif-REP]m-(A)n
motif. In the (A)n motif, the total number of alanine residues in repetitions of six or more residues is at least 20% of the total number of amino acid residues in the entire motif, the hydrophobicity of REP is -1.0 or greater, and the total number of amino acid residues in the entire motif is 580 or greater.
Inventors:
CHUANG YU CHUN (JP)
Application Number:
PCT/JP2020/027991
Publication Date:
January 28, 2021
Filing Date:
July 20, 2020
Export Citation:
Assignee:
SPIBER INC (JP)
International Classes:
D01F4/02; C07K14/435; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/12; C12P21/02
Domestic Patent References:
| WO2019022163A1 | 2019-01-31 | |||
| WO2017200659A2 | 2017-11-23 |
Other References:
DAO, A. T. N. ET AL.: "Multilateral characterization of recombinant spider silk in thermal degradation", POLYMER CHEMISTRY, vol. 8, no. 6, 2017, pages 1049 - 1060, XP055786164, DOI: 10.1039/C6PY01954D
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