Title:
MICROBIOME COMPOSITION OF FERMENTATION CULTURE SUPERNATANT OF LACTIPLANTIBACILLUS PLANTARUM STRAIN KM2 HAVING ANTI-INFLAMMATORY EFFECT
Document Type and Number:
WIPO Patent Application WO/2024/085623
Kind Code:
A1
Abstract:
The present invention relates to a microbiome composition of a fermentation culture supernatant of Lactiplantibacillus plantarum strain KM2 having an anti-inflammatory effect. It has been confirmed that the fermentation culture supernatant of the strain exhibits anti-inflammatory activity, such as suppressing nitric oxide activity and controlling the expression of inflammatory cytokines, and thus, the fermentation culture supernatant can be useful as a composition for preventing, treating, or ameliorating inflammatory diseases.
Inventors:
SUNG MOON-HEE (KR)
Application Number:
PCT/KR2023/016089
Publication Date:
April 25, 2024
Filing Date:
October 18, 2023
Export Citation:
Assignee:
KOOKMINBIO CORP (KR)
International Classes:
A61K35/747; A23L33/135; A61P29/00
Foreign References:
| KR20220135180A | 2022-10-06 | |||
| KR20220039617A | 2022-03-29 |
Other References:
YANG SOO-YEON, CHAE SEUNG A, BANG WON YEONG, LEE MINJEE, BAN O-HYUN, KIM SOO-JUNG, JUNG YOUNG HOON, YANG JUNGWOO: "Anti-inflammatory potential of Lactiplantibacillus plantarum IDCC 3501 and its safety evaluation.", BRAZILIAN JOURNAL OF MICROBIOLOGY, SOCIEDADE BRASILEIRA DE MICROBIOLOGIA,BRAZILIAN SOCIETY FOR MICROBIOLOGY, BR, vol. 52, no. 4, 1 December 2021 (2021-12-01), BR , pages 2299 - 2306, XP009553994, ISSN: 1517-8382, DOI: 10.1007/s42770-021-00603-2
FENGLIAN MA: "Lactiplantibacillus plantarum-12 Alleviates Inflammation and Colon Cancer Symptoms in AOM/DSS-Treated Mice through Modulating the Intestinal Microbiome and Metabolome", NUTRIENTS, M D P I AG, CH, vol. 14, no. 9, 3 May 2022 (2022-05-03), CH , pages 1916, XP093160927, ISSN: 2072-6643, DOI: 10.3390/nu14091916
FENGLIAN MA: "Lactiplantibacillus plantarum-12 Alleviates Inflammation and Colon Cancer Symptoms in AOM/DSS-Treated Mice through Modulating the Intestinal Microbiome and Metabolome", NUTRIENTS, M D P I AG, CH, vol. 14, no. 9, 3 May 2022 (2022-05-03), CH , pages 1916, XP093160927, ISSN: 2072-6643, DOI: 10.3390/nu14091916
Attorney, Agent or Firm:
TAEBAEK INTELLECTUAL PROPERTY LAW FIRM (KR)
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