METHOD FOR PREPARING GLP-1 RECEPTOR AGONIST INTERMEDIATE - HANGZHOU ZHONGMEIHUADONG PHARMACEUTICAL CO LTD

Title:

METHOD FOR PREPARING GLP-1 RECEPTOR AGONIST INTERMEDIATE

Document Type and Number:

WIPO Patent Application WO/2023/029979

Kind Code:

A1

Abstract:

Provided is a method for preparing (S,Z)-3-(2-(4-((3,4-dichlorobenzyl)oxy)phenyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-hydroxyacrylic acid and (S)-3-((S)-2-(4-((3,4-dichlorobenzyl)oxy)phenyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-(((S)-1-phenylpropyl)amino)propanoic acid. The preparation method has advantages of low cost, high yield and controllable quality, and is more suitable for industrial production.

More Like This:

WO/1995/021614	NEW PROTEIN TRAFFICKING INHIBITORS
WO/1995/003343	PROTON-TRANSFER, LOW SELF-ABSORBING CHROMOPHORES FOR USE IN SCINTILLATORS
WO/2016/081010	ACID-CATALYZED ACYLATION OF 5-(HYDROXYLMETHYL)-FURFURAL REDUCTION PRODUCTS

Inventors:

HU FAN (CN)
ZHOU XINJIE (CN)
LIU DONGZHOU (CN)
HU HAIWEN (CN)
LIU KENAN (CN)

Application Number:

PCT/CN2022/112721

Publication Date:

March 09, 2023

Filing Date:

August 16, 2022

Export Citation:

Click for automatic bibliography generation Help

Assignee:

HANGZHOU ZHONGMEIHUADONG PHARMACEUTICAL CO LTD (CN)

International Classes:

C07D493/00; C07D319/20

Domestic Patent References:

WO2021238962A1	2021-12-02
WO2021242806A1	2021-12-02

Foreign References:

CN102378574A	2012-03-14
CN1764647A	2006-04-26

Attorney, Agent or Firm:

NTD UNIVATION INTELLECTUAL PROPERTY AGENCY LTD. (CN)

Download PDF:

View/Download PDF PDF Help

Previous Patent: WAVEFRONT-SPLITTING ONE-WAY ORTHOGONAL OPTICAL PATH INTERFEROMETER

Next Patent: HEATING BODY AND HEATING ATOMIZATION DEVICE