METHOD OF PREPARING CRYSTALLINE DORIPENEM

Title:

METHOD OF PREPARING CRYSTALLINE DORIPENEM

Document Type and Number:

WIPO Patent Application WO/2016/148439

Kind Code:

A2

Abstract:

The present invention relates to a method of preparing a crystalline doripenem. According to the present invention, it is possible to prepare the crystalline doripenem in a simple way without additional special equipment. In addition, all of the processes are performed in mild conditions and thus safe, and by utilizing a strongly acidic cation resin, the crystalline doripenem can be prepared with high purity and high yield. Not only that, the strongly acidic cation resin is economically advantageous in that it can be recovered after use.

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Inventors:

YOON HEE KYOON (KR)
KIM WOL YOUNG (KR)
LEE KYUNG HO (KR)

Application Number:

PCT/KR2016/002409

Publication Date:

September 22, 2016

Filing Date:

March 10, 2016

Export Citation:

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Assignee:

DAE WOONG PHARMA (KR)

International Classes:

C07D477/20; A61K31/407; C07D403/12

Attorney, Agent or Firm:

DANA PATENT LAW FIRM (New Wing Gwangsung Bldg.,,11, Yeoksam-ro 3-gil,,Gangnam-gu, Seoul, KR)

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