Title:
METHOD FOR MANUFACTURING MEDICAL MATERIAL OF WHICH HEMOSTASIS AND DEGRADATION RATES ARE CONTROLLABLE, AND MEDICAL MATERIAL MANUFACTURED THEREBY
Document Type and Number:
WIPO Patent Application WO/2022/050609
Kind Code:
A1
Abstract:
The present invention relates to a method for manufacturing a medical hemostatic material, and a medical material manufactured thereby, the method comprising: a pretreatment step of adjusting the pH of a natural cellulose substrate; a hemostatic agent adsorption step in which a hemostatic agent is adsorbed on the substrate having passed through the pretreatment step; a drying step in which the substrate having adsorbed the hemostatic agent is dried; a primary modification step in which the dried substrate is primarily modified using monochloroacetic acid (MCA); a secondary modification step in which the primarily modified substrate is secondarily modified using an organic acid aqueous solution; a washing step in which the secondarily modified substrate is washed; and a post-treatment step in which the pH of the substrate having passed through the washing step is adjusted, and thus the present invention is very biologically safe, and controls a degradation rate as necessary so as to be applicable to various situations.
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Inventors:
JEONG IN SUN (KR)
Application Number:
PCT/KR2021/011107
Publication Date:
March 10, 2022
Filing Date:
August 20, 2021
Export Citation:
Assignee:
JEONG IN SUN (KR)
International Classes:
A61L15/28; A61F13/00; A61L15/44; A61L17/10; A61L17/14
Foreign References:
| JP3576063B2 | 2004-10-13 | |||
| JP2752782B2 | 1998-05-18 | |||
| KR101699924B1 | 2017-01-25 | |||
| US20190194359A1 | 2019-06-27 |
Other References:
EUN JUNG SIM, YOUNG-GWANG KO, EUN JIN KIM*, OH KYOUNG KWON**, AND OH HYEONG KWON: "Fabrication of bioabsorbable poly(vinyl pyrrolidone) nanofibrous sheets containing blood coagulants for hemostatic application.", POLYMER SCIENCE AND TECHNOLOGY., vol. 43, no. 4, 1 January 2019 (2019-01-01), pages 629 - 639, XP055909495, ISSN: 0379-153x
Attorney, Agent or Firm:
YOON & YANG (IP) LLC (KR)
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