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Title:
HUMAN ASTROVIRUS INFECTION RECEPTOR AND APPLICATION OF SAME
Document Type and Number:
WIPO Patent Application WO/2023/013618
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a way of identifying human astrovirus (HAstV) receptor molecules and developing an HAstV infection control means. The inventors have found that an FCGRT receptor protein and a B2M protein are HAstV receptor molecules. The inventors have succeeded in providing recombinant mammalian cells and recombinant mammals into which genes for encoding the HAstV receptor molecules are introduced, and a virus production method, a chemical agent screening method, and the like which use the same, and in further providing an HAstV detection method, a chemical agent screening method, and the like which use a solid-phase support that has the HAstV receptor molecules fixed thereon.

Inventors:
NAKANISHI AKIRA (JP)
KATAYAMA KAZUHIKO (JP)
HAGA KEI (JP)
TODAKA REIKO (JP)
KOIKE SHINOBU (JP)
KUDO SHIORI (JP)
Application Number:
PCT/JP2022/029580
Publication Date:
February 09, 2023
Filing Date:
August 02, 2022
Export Citation:
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Assignee:
NAT CT GERIATRICS & GERONTOLOGY (JP)
THE KITASATO INST (JP)
International Classes:
C12N15/12; A61K39/12; A61P31/14; A61P37/04; C07K14/47; C07K14/735; C07K17/00; C12N5/10; C12N7/00; C12N7/04; C12Q1/02; C12Q1/70; G01N33/569
Domestic Patent References:
WO2012073992A12012-06-07
Foreign References:
JP2019536738A2019-12-19
JP2015512034A2015-04-23
JP2015525204A2015-09-03
Other References:
ARIAS CARLOS, DUBOIS REBECCA: "The Astrovirus Capsid: A Review", VIRUSES, MDPI, CH, vol. 9, no. 1, 1 January 2017 (2017-01-01), CH , pages 15 - 13, XP093032484, ISSN: 1999-4915, DOI: 10.3390/v9010015
Attorney, Agent or Firm:
SHIMURA Mitsuharu (JP)
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