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Title:
HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS OF PD-L1 INTERACTIONS
Document Type and Number:
WIPO Patent Application WO/2023/272720
Kind Code:
A1
Abstract:
PD-L1 inhibitors of various compound formulas, both generically and specifically are disclosed. Methods of making such PD-L1 inhibitor compounds are disclosed, both generically and specifically. Methods of using such PD-L1 inhibitor compounds singly or in combination with additional agents and compositions of such PD-L1 inhibitor compounds for the treatment of cancer and other conditions are disclosed.

Inventors:
YANG BAILING (CN)
CHEN JINHUA (CN)
LAI YANG (CN)
SUN WEI (CN)
LIANG BIN (CN)
DONG LIUYU (CN)
YE JIUYONG (CN)
KRISTJAN GUDMUNDSSON (CN)
WU JINZI JASON (CN)
Application Number:
PCT/CN2021/104258
Publication Date:
January 05, 2023
Filing Date:
July 02, 2021
Export Citation:
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Assignee:
ASCLETIS BIOSCIENCE CO LTD (CN)
International Classes:
C07D265/36; A61K31/4709; A61K31/498; A61K31/538; A61K31/5383; A61P35/00; C07D401/14; C07D403/14; C07D413/14; C07D419/14; C07D498/04
Domestic Patent References:
WO2019204609A12019-10-24
WO2002000196A22002-01-03
Foreign References:
US20180179179A12018-06-28
Other References:
"Remington's Pharmaceutical Sciences", 1985, MACK PUBLISHING COMPANY, pages: 1418
BERGE ET AL., J. PHARM. SCI, vol. 66, no. 1, 1977, pages 1 - 19
STAHL ET AL.: "Handbook of Pharmaceutical Salts: Properties, Selection, and Use", 2002, WILEY
Attorney, Agent or Firm:
PANAWELL & PARTNERS, LLC (CN)
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