Title:
GLYCAN COMPLEX, DRUG CARRIER, AND DRUG DELIVERY SYSTEM
Document Type and Number:
WIPO Patent Application WO/2024/080183
Kind Code:
A1
Abstract:
The glycan complex has a sugar chain to which a hydroxyapatite-binding molecule is bonded. The hydroxyapatite-binding molecule is at least one of an acidic peptide and estradiol.
Inventors:
NOZAWA SATOSHI (JP)
IWATA NAOYA (JP)
KAWASAKI FUMIKO (JP)
IWATA NAOYA (JP)
KAWASAKI FUMIKO (JP)
Application Number:
PCT/JP2023/035984
Publication Date:
April 18, 2024
Filing Date:
October 03, 2023
Export Citation:
Assignee:
NATIONAL UNIV CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (JP)
International Classes:
A61K47/42; A61K38/18; A61K47/28; A61K47/36; A61P19/08; C08B37/08; C08B37/10
Foreign References:
| JP2016141697A | 2016-08-08 | |||
| JP2022539652A | 2022-09-13 | |||
| CN104623721A | 2015-05-20 | |||
| JP2016516065A | 2016-06-02 | |||
| JP2000327583A | 2000-11-28 | |||
| JP2019504832A | 2019-02-21 | |||
| JP2008501307A | 2008-01-24 | |||
| JP2017522392A | 2017-08-10 | |||
| JP2017536454A | 2017-12-07 |
Other References:
MASAHIKO TERAUCHI: "Polyelectrolyte Complexes between Polycarboxylates and BMP-2 for Enhancing Osteogenic Differentiation: Effect of Chemical Structure of Polycarboxylates", POLYMERS, MOLECULAR DIVERSITY PRESERVATION INTERNATIONAL (M DP I) AG., CH, vol. 11, no. 8, 9 August 2019 (2019-08-09), CH , pages 1327, XP093159289, ISSN: 2073-4360, DOI: 10.3390/polym11081327
岩田直也 ほか, 低分子ヘパリンへの酸性ペプチド修飾による新規骨ドラッグデリバリーシステムの開発ー BMP-2との併用により骨癒合は促進するー, 日整会誌, March 2023, vol. 97(3), page S823, column of 3-Po-237, (IWATA, Naoya et al., An innovative drug delivery system for bone regeneration using acidic-peptide conjugated low molecular weight heparin, The Journal of the Japanese Orthopaedic Association), non-official translation (Combined use with BMP-2 promotes bone union)
野澤聡 ほか, 低分子ヘパリンへの酸性ペプチド修飾による新規骨ドラッグデリバリーシステムの開発ー BMP-2との併用により骨癒合は促進するー, Journal of Spine Research, 16 February 2023, vol. 14, no. 3, page 603, column of 3-4-M16-3, (NOZAWA, Satoshi et al., An innovative drug delivery system for bone regeneration using acidic-peptide conjugated low molecular weight heparin), non-official translation (Combined use with BMP-2 promotes bone union)
岩田直也 ほか, 低分子ヘパリンへの酸性ペプチド修飾による新規骨ドラッグデリバリーシステムの開発ー BMP-2との併用により骨癒合は促進するー, 日整会誌, March 2023, vol. 97(3), page S823, column of 3-Po-237, (IWATA, Naoya et al., An innovative drug delivery system for bone regeneration using acidic-peptide conjugated low molecular weight heparin, The Journal of the Japanese Orthopaedic Association), non-official translation (Combined use with BMP-2 promotes bone union)
野澤聡 ほか, 低分子ヘパリンへの酸性ペプチド修飾による新規骨ドラッグデリバリーシステムの開発ー BMP-2との併用により骨癒合は促進するー, Journal of Spine Research, 16 February 2023, vol. 14, no. 3, page 603, column of 3-4-M16-3, (NOZAWA, Satoshi et al., An innovative drug delivery system for bone regeneration using acidic-peptide conjugated low molecular weight heparin), non-official translation (Combined use with BMP-2 promotes bone union)
Attorney, Agent or Firm:
ONDA Makoto et al. (JP)
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