Title:
FATTY ACID GLYCERIDE COMPOUND CONTAINING SULFATE AND AMINE GROUP, PRODUCTION METHOD THEREFOR, AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/055203
Kind Code:
A1
Abstract:
Provided are a fatty acid glyceride compound containing sulfate and an amine group, a strain for producing same, a method for producing same, and uses of same. The fatty acid glyceride compound has antibacterial activity, particularly against vancomycin-resistant bacteria, and thus can be used for killing bacteria or inhibiting bacterial growth, or preventing or treating infections triggered or caused by bacteria.
Inventors:
OH DONG CHAN (KR)
AN JOON SOO (KR)
OH KI BONG (KR)
SHIN JONG HEON (KR)
AN JOON SOO (KR)
OH KI BONG (KR)
SHIN JONG HEON (KR)
Application Number:
PCT/KR2021/012049
Publication Date:
March 17, 2022
Filing Date:
September 06, 2021
Export Citation:
Assignee:
SEOUL NAT UNIV R&DB FOUNDATION (KR)
International Classes:
C07C305/08; A01N37/36; A01N63/20; A23K20/195; A61K31/221; A61P31/04; C12N1/20; C12P13/00; C12R1/13
Foreign References:
| KR20090100334A | 2009-09-23 | |||
| KR20030025933A | 2003-03-29 | |||
| KR20120014553A | 2012-02-17 | |||
| JP2018140940A | 2018-09-13 |
Other References:
RUZIN ALEXEY, NOVICK RICHARD P.: "Glycerol Monolaurate Inhibits Induction of Vancomycin Resistance in Enterococcus faecalis", JOURNAL OF BACTERIOLOGY (PRINT), AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 180, no. 1, 1 January 1998 (1998-01-01), US , pages 182 - 185, XP055911577, ISSN: 0021-9193, DOI: 10.1128/JB.180.1.182-185.1998
DELMOTTE, A.; CAUCHETEUR, G.: "Study of the decrease of antiseptic activity which 4,4'-diamidino-1,6-diphenoxyhexane diisethionate, isopropanolamine lauryl sulfate and hexachlorophene undergo following contact with the human skin or with blood", THERAPIE, vol. 17, no. 1, 1 January 1962 (1962-01-01), FR , pages 53 - 62, XP009535246, ISSN: 0040-5957
J. J. KABARA; R. VRABLE; M. S. F. LIE KEN JIE: "Antimicrobial lipids: Natural and synthetic fatty acids and monoglycerides", LIPIDS, SPRINGER-VERLAG, BERLIN/HEIDELBERG, vol. 12, no. 9, 1 September 1977 (1977-09-01), Berlin/Heidelberg , pages 753 - 759, XP035175367, ISSN: 1558-9307, DOI: 10.1007/BF02570908
BATOVSKA D I, TODOROVA I T, TSVETKOVA I V, NAJDENSKI H M: "Antibacterial Study of the Medium Chain Fatty Acids and Their 1-Monoglycerides: Individual Effects and Synergistic Relationships", POLISH JOURNAL OF MICROBIOLOGY, POLSKIE TOWARZYSTWO MIKROBIOLOGOW, PL, vol. 58, no. 1, 1 March 2009 (2009-03-01), PL , pages 43 - 47, XP002712728, ISSN: 1773-1331
BO YOON, JOSHUA JACKMAN, ELBA VALLE-GONZáLEZ, NAM-JOON CHO: "Antibacterial Free Fatty Acids and Monoglycerides: Biological Activities, Experimental Testing, and Therapeutic Applications", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 19, no. 4, pages 1114, XP055589473, DOI: 10.3390/ijms19041114
AN JOON SOO, HONG SEONG-HEON, SOMERS ELISABETH, LEE JAYHO, KIM BYUNG-YONG, WOO DONGHEE, KIM SUK WON, HONG HEE-JEON, JO SHIN-IL, SH: "Lenzimycins A and B, Metabolites With Antibacterial Properties From Brevibacillus sp. Associated with the Dung Beetle Onthophagus lenzii", FRONTIERS IN MICROBIOLOGY, vol. 11, no. 2705, 30 October 2020 (2020-10-30), pages 1 - 10, XP055911572
DELMOTTE, A.; CAUCHETEUR, G.: "Study of the decrease of antiseptic activity which 4,4'-diamidino-1,6-diphenoxyhexane diisethionate, isopropanolamine lauryl sulfate and hexachlorophene undergo following contact with the human skin or with blood", THERAPIE, vol. 17, no. 1, 1 January 1962 (1962-01-01), FR , pages 53 - 62, XP009535246, ISSN: 0040-5957
J. J. KABARA; R. VRABLE; M. S. F. LIE KEN JIE: "Antimicrobial lipids: Natural and synthetic fatty acids and monoglycerides", LIPIDS, SPRINGER-VERLAG, BERLIN/HEIDELBERG, vol. 12, no. 9, 1 September 1977 (1977-09-01), Berlin/Heidelberg , pages 753 - 759, XP035175367, ISSN: 1558-9307, DOI: 10.1007/BF02570908
BATOVSKA D I, TODOROVA I T, TSVETKOVA I V, NAJDENSKI H M: "Antibacterial Study of the Medium Chain Fatty Acids and Their 1-Monoglycerides: Individual Effects and Synergistic Relationships", POLISH JOURNAL OF MICROBIOLOGY, POLSKIE TOWARZYSTWO MIKROBIOLOGOW, PL, vol. 58, no. 1, 1 March 2009 (2009-03-01), PL , pages 43 - 47, XP002712728, ISSN: 1773-1331
BO YOON, JOSHUA JACKMAN, ELBA VALLE-GONZáLEZ, NAM-JOON CHO: "Antibacterial Free Fatty Acids and Monoglycerides: Biological Activities, Experimental Testing, and Therapeutic Applications", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 19, no. 4, pages 1114, XP055589473, DOI: 10.3390/ijms19041114
AN JOON SOO, HONG SEONG-HEON, SOMERS ELISABETH, LEE JAYHO, KIM BYUNG-YONG, WOO DONGHEE, KIM SUK WON, HONG HEE-JEON, JO SHIN-IL, SH: "Lenzimycins A and B, Metabolites With Antibacterial Properties From Brevibacillus sp. Associated with the Dung Beetle Onthophagus lenzii", FRONTIERS IN MICROBIOLOGY, vol. 11, no. 2705, 30 October 2020 (2020-10-30), pages 1 - 10, XP055911572
Attorney, Agent or Firm:
Y.P.LEE, MOCK & PARTNERS (KR)
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