Title:
ENRICHMENT METHOD FOR EICOSAPENTAENOIC ACID IN FISH OIL RAW MATERIAL
Document Type and Number:
WIPO Patent Application WO/2024/000977
Kind Code:
A1
Abstract:
The present invention belongs to the technical field of substance purification, and specifically provides an enrichment method for eicosapentaenoic acid in a fish oil raw material. The enrichment method provided in the present invention comprises the following steps: feeding a fish oil raw material into a double-column simulation moving bed, and sequentially carrying out sample loading, layer unfolding, first internal circulation, sample loading-collection, second internal circulation and rear impurity discharging, wherein the double-column simulation moving bed comprises a first chromatographic column and a second chromatographic column, and the mobile phase of the double-column simulation moving bed is an alcohol aqueous solution. By means of the enrichment method provided in the present invention, EPA with a purity ≥ 98.5% can be separated from a fish oil raw material, and the enrichment method provided in the present invention has a low solvent amount and a high yield, and facilitates automatic and continuous production.
Inventors:
LU FENG (CN)
XIANG LIN (CN)
GUO FURUI (CN)
JIA KUN (CN)
QI WEI (CN)
LI SHENGYING (CN)
XIANG LIN (CN)
GUO FURUI (CN)
JIA KUN (CN)
QI WEI (CN)
LI SHENGYING (CN)
Application Number:
PCT/CN2022/129279
Publication Date:
January 04, 2024
Filing Date:
November 02, 2022
Export Citation:
Assignee:
JIANGSU HANBON SCIEBCE AND TECH CO LTD (CN)
International Classes:
C07C51/47; C07C57/03
Foreign References:
| CN115010596A | 2022-09-06 | |||
| CN103508876A | 2014-01-15 | |||
| CN105980026A | 2016-09-28 | |||
| CN103787863A | 2014-05-14 | |||
| CN115073292A | 2022-09-20 |
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