Title:
ELDECALCITOL CRYSTAL FORM, PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD AND USE
Document Type and Number:
WIPO Patent Application WO/2019/052470
Kind Code:
A1
Abstract:
Disclosed are an eldecalcitol crystal form, a pharmaceutical composition and a preparation method and the use. The eldecalcitol crystal form has characteristic peaks at the diffraction angle 2θ = 5.2° ± 0.2°, 10.4° ± 0.2°, 15.6° ± 0.2°, 20.9° ± 0.2° and 31.5° ± 0.2° in the X-ray powder diffraction pattern using the radiation source of Cu-Kα. The eldecalcitol crystal form of the invention has excellent stability, high bioavailability, and a preparation method simple to operate, low cost and with simple post-treatment.
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Inventors:
WANG MENG (CN)
WANG DONG (CN)
WANG FANGDAO (CN)
SU QIFENG (CN)
WU WEIFENG (CN)
KUANG ZHENGXIA (CN)
WANG DONG (CN)
WANG FANGDAO (CN)
SU QIFENG (CN)
WU WEIFENG (CN)
KUANG ZHENGXIA (CN)
Application Number:
PCT/CN2018/105239
Publication Date:
March 21, 2019
Filing Date:
September 12, 2018
Export Citation:
Assignee:
CHEMVON BIOTECHNOLOGY CO LTD (CN)
International Classes:
A61K31/593; C07C401/00; A61P19/10
Foreign References:
CN107540589A | 2018-01-05 | |||
CN106336369A | 2017-01-18 | |||
CN1223639A | 1999-07-21 |
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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