Title:
DRY HEMOSTATIC COMPOSITIONS AND METHODS FOR THEIR PREPARATION
Document Type and Number:
WIPO Patent Application WO2003007845
Kind Code:
A9
Abstract:
Dry cross-linked gelatin compositions are prepared that rapidly re-hydrate to produce gelatin hydrogels suitable as hemostatic sealants. Gelatin is cross-linked in the presence of certain re-hydration aids, such as polyethylene glycol, polyvinylprovidone, and dextran, in order to produce a dry cross-linked gelatin powder. The use of the re-hydration aids has been found to substantially increase the re-hydration rate in the presence of an aqueous re-hydration medium, typically thrombin-containing saline.
Inventors:
QIAN ZHEN
OSAWA EDWARD A
REICH CARY J
OSAWA EDWARD A
REICH CARY J
Application Number:
PCT/US2002/020022
Publication Date:
April 01, 2004
Filing Date:
June 21, 2002
Export Citation:
Assignee:
BAXTER INT (US)
BAXTER HEALTHCARE SA (CH)
BAXTER HEALTHCARE SA (CH)
International Classes:
A61L15/16; A61F2/02; A61K38/39; A61K38/48; A61L24/00; A61L24/10; C09H9/00; (IPC1-7): A61F2/02; A61K38/39
Download PDF: