Title:
DRIED PRENCSO COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2022/202994
Kind Code:
A1
Abstract:
The present description discloses: a dried PRENCSO composition having improved storage stability; and a lachrymatory factor generation kit in which the dried PRENCSO composition is used. The dried PRENCSO composition according to the present disclosure is characterized by comprising PRENCSO and a sugar. The present disclosure also relates to a method for producing a dried PRENCSO composition, the method comprising drying a solution containing PRENCSO and a sugar. The present disclosure also relates to a lachrymatory factor generation kit including the dried PRENCSO composition and a dried enzyme composition that comprises alliinase and a lachrymatory factor synthase (LFS) and has a dried form. The present disclosure also relates to a method for generating a lachrymatory factor by bringing the dried PRENCSO composition and the dried enzyme composition into contact with water.
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Inventors:
UEYAMA MASAE (JP)
AOYAGI MORIHIRO (JP)
AOYAGI MORIHIRO (JP)
Application Number:
PCT/JP2022/013961
Publication Date:
September 29, 2022
Filing Date:
March 24, 2022
Export Citation:
Assignee:
HOUSE FOODS GROUP INC (JP)
International Classes:
A61K38/54; A61K9/14; A61K9/19; A61K31/198; A61K47/26; A61K47/36; A61K49/00; A61P27/04; A61P31/04; C07C315/06; C07C317/48
Domestic Patent References:
| WO2005067907A1 | 2005-07-28 | |||
| WO2002020808A1 | 2002-03-14 | |||
| WO2003074707A1 | 2003-09-12 |
Foreign References:
| JP2019076088A | 2019-05-23 | |||
| JP2008285476A | 2008-11-27 | |||
| JP2017093430A | 2017-06-01 | |||
| JP2007267639A | 2007-10-18 | |||
| JP2008285476A | 2008-11-27 | |||
| JP2021051876A | 2021-04-01 |
Other References:
FREEMAN GEORGE G., ROBERT J. WHENHAM: "The use of synthetic (±)-s-1-propyl-L-cysteine sulphoxide and of alliinase preparations in studies of flavour changes resulting from processing of onion (allium cepa L.)", IMMUNOGOLD LABELLING TO LOCALIZE POLYPHENOL OXIDASE (PPO) DURING WILTING OF RED CLOVER LEAF TISSUE AND THE EFFECT OF REMOVING CELLULAR MATRICES ON PPO PROTECTION OF GLYCEROL-BASED LIPID IN THE RUMEN., JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE FE, vol. 26, 30 September 1975 (1975-09-30), pages 1333 - 1346, XP055969460, ISSN: 1097-0010, DOI: 10.1002/jsfa.2740260912
MIWA, AKIRA; MINAMI, HIDEMI; TSUGE, HIDEYA: "Water on Freeze-Drying of Pharmaceuticals : Stabilization of Pharmaceutical Products by Sugars and Sugar-Alcohols", TOKETSU OYOBI KANSO KENKYUKAI KAISHA - JAPANESE JOURNAL OFFREEZING AND DRYING, TOKETSU OYOBI KANSO KENKYUKAI, TOKYO,, JP, vol. 33, 1 January 1987 (1987-01-01), JP , pages 93 - 96, XP009539756, ISSN: 0288-8297, DOI: 10.20585/touketsukansokaishi.33.0_93
NISHIBORI SUKIE, KAZUKO NAMIKI: " Free Sugar Contents in Onion Bulbs of Different Cultivars and Different Production Areas, and their Changes by Storage and Gamma-Irradiation", NIPPON SHOKUHIN KOGYO GAKKAISHI - JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, NIPPON SHOKUHIN KAGAKUKOUGAKUKAI, JP, vol. 29, no. 5, 1 January 1982 (1982-01-01), JP , pages 271 - 276, XP055969458, ISSN: 0029-0394, DOI: 10.3136/NSKKK1962.29.5_271
KREST I; KEUSGEN M: "Stabilization and pharmaceutical use of alliinase", PHARMAZIE, GOVI VERLAG PHARMAZEUTISCHER VERLAG GMBH, DE, vol. 54, no. 4, 1 April 1999 (1999-04-01), DE , pages 289 - 293, XP001526435, ISSN: 0031-7144
MIWA, AKIRA; MINAMI, HIDEMI; TSUGE, HIDEYA: "Water on Freeze-Drying of Pharmaceuticals : Stabilization of Pharmaceutical Products by Sugars and Sugar-Alcohols", TOKETSU OYOBI KANSO KENKYUKAI KAISHA - JAPANESE JOURNAL OFFREEZING AND DRYING, TOKETSU OYOBI KANSO KENKYUKAI, TOKYO,, JP, vol. 33, 1 January 1987 (1987-01-01), JP , pages 93 - 96, XP009539756, ISSN: 0288-8297, DOI: 10.20585/touketsukansokaishi.33.0_93
NISHIBORI SUKIE, KAZUKO NAMIKI: " Free Sugar Contents in Onion Bulbs of Different Cultivars and Different Production Areas, and their Changes by Storage and Gamma-Irradiation", NIPPON SHOKUHIN KOGYO GAKKAISHI - JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, NIPPON SHOKUHIN KAGAKUKOUGAKUKAI, JP, vol. 29, no. 5, 1 January 1982 (1982-01-01), JP , pages 271 - 276, XP055969458, ISSN: 0029-0394, DOI: 10.3136/NSKKK1962.29.5_271
KREST I; KEUSGEN M: "Stabilization and pharmaceutical use of alliinase", PHARMAZIE, GOVI VERLAG PHARMAZEUTISCHER VERLAG GMBH, DE, vol. 54, no. 4, 1 April 1999 (1999-04-01), DE , pages 289 - 293, XP001526435, ISSN: 0031-7144
Attorney, Agent or Firm:
HIRAKI & ASSOCIATES (JP)
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