Title:
DIPHENYL ALKANE COMPOUND AND PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/194128
Kind Code:
A1
Abstract:
The present invention belongs to the technical field of medicine, and relates to a diphenyl alkane compound and a preparation method therefor, and a pharmaceutical composition and the use thereof. Specifically disclosed are a diphenyl alkane compound of formula (I), 1-fluoro-3-methoxy-5-phenethyl benzene (II) and a preparation method therefor, and the use thereof in the preparation of drugs for preventing or treating metabolic syndrome. The compound has a significant effect against metabolic syndrome, and can be used in the clinical treatment of metabolic syndrome in the form of a monomer or pharmaceutical composition.
Inventors:
QIANG GUIFEN (CN)
JI TENGFEI (CN)
DU GUANHUA (CN)
MA PENG (CN)
WANG ZIJING (CN)
XU TIANSHU (CN)
HE PING (CN)
SUN MINGXIA (CN)
YANG XIUYING (CN)
JI TENGFEI (CN)
DU GUANHUA (CN)
MA PENG (CN)
WANG ZIJING (CN)
XU TIANSHU (CN)
HE PING (CN)
SUN MINGXIA (CN)
YANG XIUYING (CN)
Application Number:
PCT/CN2022/080862
Publication Date:
September 22, 2022
Filing Date:
March 15, 2022
Export Citation:
Assignee:
INST OF MATERIA MEDICA CHINESE ACADEMY OF MEDICAL SCICENCES (CN)
International Classes:
C07C15/18; A61K31/03; A61P3/00; C07C15/16; C07C17/354; C07C25/18
Foreign References:
| CN101917980A | 2010-12-15 | |||
| US20120052757A1 | 2012-03-01 | |||
| CN101528709A | 2009-09-09 | |||
| US5232946A | 1993-08-03 |
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