Title:
CYTOKINE PRODUCTION ADJUSTMENT AGENT
Document Type and Number:
WIPO Patent Application WO/2024/058255
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide an agent for adjusting cytokine production by lipopolysaccharide derived from Escherichia coli, or an agent for adjusting TLR4 activation by lipopolysaccharide derived from Escherichia coli. The present invention provides: an agent for adjusting cytokine production by lipopolysaccharide derived from Escherichia coli, the agent including lipopolysaccharide derived from bacteria belonging to genus Paracoccus; or an agent for adjusting TLR4 activation by lipopolysaccharide derived from Escherichia coli, the agent including lipopolysaccharide derived from bacteria belonging to genus Paracoccus.
Inventors:
KUWAHARA DAICHI (JP)
FUJIMOTO YUKARI (JP)
FUJIMOTO YUKARI (JP)
Application Number:
PCT/JP2023/033614
Publication Date:
March 21, 2024
Filing Date:
September 14, 2023
Export Citation:
Assignee:
ENEOS CORP (JP)
UNIV KEIO (JP)
UNIV KEIO (JP)
International Classes:
A61K31/739; A23L33/135; A61K35/74; A61P31/04; A61P37/04; A61P43/00; C08B37/00; C12N1/20
Other References:
石橋 卓, S01 発酵法により生産された天然アスタキサンチンの用途と機能, 公益社団法人 日本農芸化学会 中部支部 日本農芸化学会中部支部第181 回例会 講演要旨集, 2017, pp. 1-4
WILKINSON, B.J. ; HINDAHL, M.S. ; GALBRAITH, L. ; WILKINSON, S.G.: "Lipopolysaccharide of Paracoccus denitrificans ATCC13543", FEMS MICROBIOLOGY LETTERS, NO LONGER PUBLISHED BY ELSEVIER, vol. 37, no. 1, 1 October 1986 (1986-10-01), pages 63 - 67, XP025957858, ISSN: 0378-1097, DOI: 10.1111/j.1574-6968.1986.tb01767.x
TAKEUCHI, OSAMU; AKIRA, SHIZUO: "3. Bacterial infection and TLR", EXPERIMENTAL MEDICINE, YODOSHA CO., LTD., JP, vol. 18, no. 15, Suppl., 1 January 2000 (2000-01-01), JP , pages 145 - 149, XP009553593, ISSN: 0288-5514
HENMI HIROAKI, AKIRA SHIZUO: "TRL and protection against infection", JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, BIOMEDICAL DRUGS PUBLICATION, JP, vol. 195, no. 11-12, 1 January 2000 (2000-01-01), JP , pages 828 - 829, XP009553595, ISSN: 0039-2359
MATSUMOTO FUMI, MITAKE KENSUKE: "Toll-like receptor and its regulation", ARERUGI - JAPANESE JOURNAL OF ALLERGOLOGY, TOKYO., JP, vol. 54, no. 12, 1 January 2005 (2005-01-01), JP , pages 1413 - 1418, XP009553597, ISSN: 0021-4884
WILKINSON, B.J. ; HINDAHL, M.S. ; GALBRAITH, L. ; WILKINSON, S.G.: "Lipopolysaccharide of Paracoccus denitrificans ATCC13543", FEMS MICROBIOLOGY LETTERS, NO LONGER PUBLISHED BY ELSEVIER, vol. 37, no. 1, 1 October 1986 (1986-10-01), pages 63 - 67, XP025957858, ISSN: 0378-1097, DOI: 10.1111/j.1574-6968.1986.tb01767.x
TAKEUCHI, OSAMU; AKIRA, SHIZUO: "3. Bacterial infection and TLR", EXPERIMENTAL MEDICINE, YODOSHA CO., LTD., JP, vol. 18, no. 15, Suppl., 1 January 2000 (2000-01-01), JP , pages 145 - 149, XP009553593, ISSN: 0288-5514
HENMI HIROAKI, AKIRA SHIZUO: "TRL and protection against infection", JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, BIOMEDICAL DRUGS PUBLICATION, JP, vol. 195, no. 11-12, 1 January 2000 (2000-01-01), JP , pages 828 - 829, XP009553595, ISSN: 0039-2359
MATSUMOTO FUMI, MITAKE KENSUKE: "Toll-like receptor and its regulation", ARERUGI - JAPANESE JOURNAL OF ALLERGOLOGY, TOKYO., JP, vol. 54, no. 12, 1 January 2005 (2005-01-01), JP , pages 1413 - 1418, XP009553597, ISSN: 0021-4884
Attorney, Agent or Firm:
KOBAYASHI Hiroshi et al. (JP)
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