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Title:
CYCLOPENTANOPERHYDROPHENANTHRENE FRAMEWORK COMPOUNDS AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2015/158163
Kind Code:
A1
Abstract:
The present invention relates to cyclopentanoperhydrophenanthrene framework compounds and a preparation method therefor. The compounds have certain biological activity, can also be used as an intermediate synthon for synthesizing some compounds with a special structure, and relate to the field of pharmaceutical chemistry. The compounds and salts thereof can be used as lead compounds for synthesizing medicines, pesticides and new materials, and can be used for screening and preparing new compounds with important application value by chemical, biological and medical means on such basis, thereby achieving the goal of creating new medicines.

Inventors:
HUANG WEN (CN)
Application Number:
PCT/CN2015/070372
Publication Date:
October 22, 2015
Filing Date:
January 08, 2015
Export Citation:
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Assignee:
SICHUAN JINGHUACHUANG BIOTECHNOLOGY CORP (CN)
International Classes:
C07J71/00; C07J9/00; C07J75/00
Foreign References:
CN1652794A2005-08-10
CN1821260A2006-08-23
FR2743561B11998-02-20
GB843664A1960-08-10
TWI393725B2013-04-21
CN101597317A2009-12-09
Other References:
ZHENG, WEI ET AL.: "The Design and Synthesis of diosgenin anti-tumor derivatives (III", WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 26, no. 2, 28 February 2011 (2011-02-28), pages 107 - 111
ANETA M. TOMKIEL ET AL.: "Electrochemical synthesis of glycoconjugates of 3b-hydroxy-D5- steroids by using non-activated sugars and steroidal thioethers", TETRAHEDON, vol. 69, 15 August 2013 (2013-08-15), pages 8904 - 8913, XP028708798
FU, XIAOLI ET AL.: "Synthesis of diosgenin derivatives and their antithrombotic activity", DRUGS & CLINIC, vol. 26, no. 1, 31 January 2011 (2011-01-31), pages 46 - 49
ZHANG, RUI ET AL.: "Study on the synthesis and antitumor activities of diosgenyl saponin derivatives", WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 28, no. 3, 31 March 2013 (2013-03-31), pages 229 - 231
Attorney, Agent or Firm:
GOLDENGATE (CN)
北京金阙华进专利事务所(普通合伙) (CN)
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