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Title:
CYCLIC SULFONE COMPOUND AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/104506
Kind Code:
A1
Abstract:
A cyclic sulfone compound and a preparation method therefor, a pharmaceutical composition thereof and use thereof. Specifically, the cyclic sulfone compound and a pharmaceutically acceptable salt are represented by formula (I), and can be used in the preparation of a CXCR2 antagonist, and can be used in the preparation of a drug for preventing and/or treating CXCR2 receptor-mediated diseases.

Inventors:
XU HENG (CN)
CHEN XIAOGUANG (CN)
DONG YI (CN)
JI MING (CN)
CHEN JIAJING (CN)
JIN JING (CN)
XUE NINA (CN)
WANG MINGJIN (CN)
Application Number:
PCT/CN2020/132544
Publication Date:
June 03, 2021
Filing Date:
November 28, 2020
Export Citation:
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Assignee:
INST OF MATERIA MEDICA CHINESE ACADEMY OF MEDICAL SCICENCES (CN)
International Classes:
C07D335/06; A61K31/382; A61P11/00; A61P11/06; A61P19/02; A61P25/04; A61P25/16; A61P25/28; A61P35/00; A61P37/00
Domestic Patent References:
WO2010063802A12010-06-10
WO2010091543A12010-08-19
WO2012080457A12012-06-21
Foreign References:
CN1575273A2005-02-02
CN102171183A2011-08-31
CN101772485A2010-07-07
CN101472477A2009-07-01
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