Title:
CYCLIC SULFONE COMPOUND AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/104506
Kind Code:
A1
Abstract:
A cyclic sulfone compound and a preparation method therefor, a pharmaceutical composition thereof and use thereof. Specifically, the cyclic sulfone compound and a pharmaceutically acceptable salt are represented by formula (I), and can be used in the preparation of a CXCR2 antagonist, and can be used in the preparation of a drug for preventing and/or treating CXCR2 receptor-mediated diseases.
Inventors:
XU HENG (CN)
CHEN XIAOGUANG (CN)
DONG YI (CN)
JI MING (CN)
CHEN JIAJING (CN)
JIN JING (CN)
XUE NINA (CN)
WANG MINGJIN (CN)
CHEN XIAOGUANG (CN)
DONG YI (CN)
JI MING (CN)
CHEN JIAJING (CN)
JIN JING (CN)
XUE NINA (CN)
WANG MINGJIN (CN)
Application Number:
PCT/CN2020/132544
Publication Date:
June 03, 2021
Filing Date:
November 28, 2020
Export Citation:
Assignee:
INST OF MATERIA MEDICA CHINESE ACADEMY OF MEDICAL SCICENCES (CN)
International Classes:
C07D335/06; A61K31/382; A61P11/00; A61P11/06; A61P19/02; A61P25/04; A61P25/16; A61P25/28; A61P35/00; A61P37/00
Domestic Patent References:
WO2010063802A1 | 2010-06-10 | |||
WO2010091543A1 | 2010-08-19 | |||
WO2012080457A1 | 2012-06-21 |
Foreign References:
CN1575273A | 2005-02-02 | |||
CN102171183A | 2011-08-31 | |||
CN101772485A | 2010-07-07 | |||
CN101472477A | 2009-07-01 |
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