CRYSTAL FORMS OF GLUCOSAMINE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF

Title:

CRYSTAL FORMS OF GLUCOSAMINE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2022/253234

Kind Code:

A1

Abstract:

The present invention relates to a crystal form I and crystal form II of the compound 2-N-4,6-di-O-tributyryl-D-glucosamine, and a preparation method therefor and the use thereof. The crystal form I and crystal form II obtained in the present invention have high water solubility and crystal form stability, and can be better used in pharmacy.

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Inventors:

LYU JIASHENG (CN)
GU JIAMIN (CN)
GE JIAN (CN)

Application Number:

PCT/CN2022/096315

Publication Date:

December 08, 2022

Filing Date:

May 31, 2022

Export Citation:

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Assignee:

RISEN SUZHOU PHARMA TECH CO LTD (CN)

International Classes:

C07H13/04; A61K31/7024; A61P19/00; A61P19/02; A61P19/10; A61P29/00; C07H1/06

Foreign References:

CN109929001A	2019-06-25
CN101111243A	2008-01-23
CN1953660A	2007-04-25
CN201711364533A	2017-12-18

Other References:

CHI-HIEN DANG, NGUYEN CONG-HAO, NGUYEN THANH-DANH, IM CHAN: "Synthesis and characterization of N-acyl-tetra-O-acyl glucosamine derivatives", RSC ADVANCES, vol. 4, no. 12, 1 January 2014 (2014-01-01), pages 6239 - 6245, XP055619686, DOI: 10.1039/c3ra46007j

Attorney, Agent or Firm:

CHINA PAT INTELLECTUAL PROPERTY OFFICE (CN)

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