Title:
CORYNEBACTERIUM SP. MUTANT MICROORGANISM PRODUCING L-GLUTAMIC ACID AND METHOD FOR PRODUCING L-GLUTAMIC ACID USING SAME
Document Type and Number:
WIPO Patent Application WO/2024/014700
Kind Code:
A1
Abstract:
The present invention relates to a Corynebacterium sp. mutant microorganism producing L-glutamic acid and a method for producing L-glutamic acid using same and, more specifically, to a novel mutant deoxyribose phosphate aldorase involved in the L-glutamic acid biosynthesis pathway, a polynucleotide, a transformant, and a method for producing L-glutamic acid using same. According to the present invention, the mutant deoxyribose phosphate aldorase has a modified enzymatic activity as at one or more amino acid residues in the amino acid sequence constituting the deoxyribose phosphate aldorase are deleted. Thus, a recombinant microorganism containing the mutant enzyme can efficiently produce L-glutamic acid.
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Inventors:
LEE SUN HEE (KR)
KIM HYUN HO (KR)
KIM DONG HYUN (KR)
KIM HYUN SOOK (KR)
PARK SEOK HYUN (KR)
PARK JOON HYUN (KR)
KIM HYUN HO (KR)
KIM DONG HYUN (KR)
KIM HYUN SOOK (KR)
PARK SEOK HYUN (KR)
PARK JOON HYUN (KR)
Application Number:
PCT/KR2023/007171
Publication Date:
January 18, 2024
Filing Date:
May 25, 2023
Export Citation:
Assignee:
DAESANG CORP (KR)
International Classes:
C12N9/88; C12N15/77; C12P13/14
Domestic Patent References:
| WO2022055094A1 | 2022-03-17 |
Foreign References:
| KR20210032417A | 2021-03-24 | |||
| JP2007074995A | 2007-03-29 | |||
| KR102277407B1 | 2021-07-14 |
Other References:
DATABASE Protein 27 February 2016 (2016-02-27), ANONYMOUS : "2-deoxyribose-5-phosphate aldolase [Corynebacterium glutamicum] ", XP093128515, retrieved from NCBI Database accession no. ALZ99163.1
Attorney, Agent or Firm:
PARK, Hyuk (KR)
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