Title:
COMPOUND HAVING PHOTOCLEAVABLE SITE, LINKER, AND SCREENING METHOD USING SAME
Document Type and Number:
WIPO Patent Application WO/2023/054636
Kind Code:
A1
Abstract:
The present invention relates to a compound having: (i) a photocleavable site; and (ii) at least one selected from the group consisting of a target substance binding site and an anchor binding site.
Inventors:
SAITO RIE (JP)
NAKANO KAZUHIKO (JP)
OHTA ATSUSHI (JP)
EMURA TAKASHI (JP)
NAKANO KAZUHIKO (JP)
OHTA ATSUSHI (JP)
EMURA TAKASHI (JP)
Application Number:
PCT/JP2022/036570
Publication Date:
April 06, 2023
Filing Date:
September 29, 2022
Export Citation:
Assignee:
CHUGAI PHARMACEUTICAL CO LTD (JP)
International Classes:
C07D495/04; C07F9/6524; C07K7/06; C07K7/08; C07K17/00
Domestic Patent References:
| WO2013100132A1 | 2013-07-04 | |||
| WO2018225864A1 | 2018-12-13 | |||
| WO2018143145A1 | 2018-08-09 |
Foreign References:
| KR101750658B1 | 2017-06-27 | |||
| JP2010024147A | 2010-02-04 | |||
| JP2015017047A | 2015-01-29 |
Other References:
SHIBU EDAKKATTUPARAMBIL S., ONO KENJI, SUGINO SAKIKO, NISHIOKA AYAMI, YASUDA AKIKAZU, SHIGERI YASUSHI, WAKIDA SHIN-ICHI, SAWADA MA: "Photouncaging Nanoparticles for MRI and Fluorescence Imaging in Vitro and in Vivo", ACS NANO, AMERICAN CHEMICAL SOCIETY, US, vol. 7, no. 11, 26 November 2013 (2013-11-26), US , pages 9851 - 9859, XP093053794, ISSN: 1936-0851, DOI: 10.1021/nn4043699
OKADA, Y. ET AL., J. ORG. CHEM, vol. 78, 2013, pages 320
TAKAHASHI, DYAMAMOTO, T: "Tetrahedron Lett.", vol. 53, 2012, pages: 1936
TAKAHASHI, D. ET AL., ANGEW. CHEM. INT. ED., vol. 56, 2017, pages 7803
MOLECULES., vol. 24, no. 8, April 2019 (2019-04-01), pages 1629
PROC. NATL. ACAD. SCI. USA., vol. 108, no. 28, 12 July 2011 (2011-07-12), pages 11399 - 11404
LITERATURE NATURE PROTOCOLS, vol. 10, 2015, pages 508 - 516
HELV. CHIM. ACTA, vol. 90, pages 297 - 310
YOKOGAWA TKITAMURA YNAKAMURA DOHNO SNISHIKAWA K, NUCLEIC ACIDS RESEARCH, vol. 38, 2010, pages e89
OKADA, Y. ET AL., J. ORG. CHEM, vol. 78, 2013, pages 320
TAKAHASHI, DYAMAMOTO, T: "Tetrahedron Lett.", vol. 53, 2012, pages: 1936
TAKAHASHI, D. ET AL., ANGEW. CHEM. INT. ED., vol. 56, 2017, pages 7803
MOLECULES., vol. 24, no. 8, April 2019 (2019-04-01), pages 1629
PROC. NATL. ACAD. SCI. USA., vol. 108, no. 28, 12 July 2011 (2011-07-12), pages 11399 - 11404
LITERATURE NATURE PROTOCOLS, vol. 10, 2015, pages 508 - 516
HELV. CHIM. ACTA, vol. 90, pages 297 - 310
YOKOGAWA TKITAMURA YNAKAMURA DOHNO SNISHIKAWA K, NUCLEIC ACIDS RESEARCH, vol. 38, 2010, pages e89
Attorney, Agent or Firm:
HASEGAWA Yoshiki et al. (JP)
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