COMPOSITIONS AND METHODS FOR TREATING VAGINAL ATROPHY

Title:

COMPOSITIONS AND METHODS FOR TREATING VAGINAL ATROPHY

Document Type and Number:

WIPO Patent Application WO/2024/054524

Kind Code:

A1

Abstract:

Compositions and methods for treating one or more symptoms associated with vaginal atrophy or discomfort are disclosed. The compositions include an effective amount of one or more of the active agents selected from pectin (P), hyaluronic acid (HA), and collagen (Cg), in a pharmaceutically acceptable carrier, for vaginal delivery. The disclosed compositions are useful in treating one or more symptoms associated with vaginal atrophy. Example subjects include postmenopausal women or premenopausal women who experience these symptoms as a result of breastfeeding, intensive vaginal douching, cigarette smoking, autoimmune conditions such as Sjogren's syndrome, pathologic conditions such as diabetes, premature ovarian insufficiency, bilateral oophorectomy, ovarian failure due to radiation or arterial embolization, hypothalamic-pituitary disorders. Additionally, the disclosed compositions are useful in generally alleviating vaginal discomfort such as pH imbalance, vaginal dryness, burning, itching, vaginal discomfort, pain and burning when urinating, dyspareunia (painful sex), and spotting during intercourse.

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Inventors:

AKANDE JANET (US)
ADEDOYIN OREOLUWA (US)

Application Number:

PCT/US2023/032117

Publication Date:

March 14, 2024

Filing Date:

September 06, 2023

Export Citation:

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Assignee:

AKANDE JANET MUBO (US)
ADEDOYIN OREOLUWA OLUFUNMILAYO (US)

International Classes:

A61K31/732; A61K9/00; A61K31/728; A61K38/39; A61P15/02

Domestic Patent References:

WO2005049100A1	2005-06-02
WO2019213464A1	2019-11-07

Foreign References:

US20030219472A1

2003-11-27

Attorney, Agent or Firm:

FAHRNI, Mengmeng, Anne (US)

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Claims:

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Description:

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