Title:
COMPOSITION FOR PREVENTION, ALLEVIATION, OR TREATMENT OF BONE DISEASE, CONTAINING SALVIANOLIC ACID AS ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2024/048998
Kind Code:
A1
Abstract:
The present invention relates to a composition for prevention, alleviation, or treatment of bone disease, containing salvianolic acid as an active ingredient, the salvianolic acid of the present invention, specifically, salvianolic acid A or methyl salvionolate A having an excellent effect of promoting osteoblast differentiation, methyl salvionolate A having an excellent effect of inhibiting osteoclast differentiation, and salvianolic acid A, when administered in an ovariectomized mouse, having an excellent effect of inhibiting bone loss, and thus the composition of the present invention, containing salvianolic acid A or methyl salvionolate A as an active ingredient may be usefully employed as an agent for prevention, alleviation, or treatment of bone disease.
Inventors:
HA HYUN IL (KR)
YANG HYUN (KR)
GU DONG RYUN (KR)
RYUK JIN AH (KR)
KIM SEONG CHEOL (KR)
YANG HYUN (KR)
GU DONG RYUN (KR)
RYUK JIN AH (KR)
KIM SEONG CHEOL (KR)
Application Number:
PCT/KR2023/010423
Publication Date:
March 07, 2024
Filing Date:
July 19, 2023
Export Citation:
Assignee:
KOREA INST ORIENTAL MEDICINE (KR)
International Classes:
A61K31/216; A23K20/111; A23L33/10; A61P19/00
Foreign References:
| KR20190135263A | 2019-12-06 | |||
| KR20180055519A | 2018-05-25 | |||
| KR20210081164A | 2021-07-01 | |||
| KR20070056448A | 2007-06-04 | |||
| CN103690519A | 2014-04-02 | |||
| KR102465894B1 | 2022-11-11 |
Attorney, Agent or Firm:
CHOI, Kyu Whan (KR)
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