COMPOSITION CONTAINING PEPTIDES HAVING SKIN-LIGHTENING EFFECT

Title:

COMPOSITION CONTAINING PEPTIDES HAVING SKIN-LIGHTENING EFFECT

Document Type and Number:

WIPO Patent Application WO/2024/048890

Kind Code:

A1

Abstract:

The present invention relates to pharmaceutical agents, cosmetics, medical devices, and the like, containing novel skin-lightening functional peptides. The present inventors found that the RMNE1 peptide of SEQ ID NO: 1 and a variant thereof exhibit low cytotoxicity as well as high cell permeability and skin penetrability and show an excellent skin-lightening effect.

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Inventors:

PARK CHANHO (KR)
CHO SEONGMIN (KR)
SONG EE CHAN (KR)
SHIN YUNGYEONG (KR)

Application Number:

PCT/KR2023/004728

Publication Date:

March 07, 2024

Filing Date:

April 07, 2023

Export Citation:

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Assignee:

REMEDI CO LTD (KR)

International Classes:

A61K8/64; A61K38/10; A61L15/32; A61L15/44; A61L26/00; A61L27/22; A61L27/54; A61P17/00; A61Q19/02

Domestic Patent References:

WO2016034541A1	2016-03-10
WO2021033831A1	2021-02-25
WO2020088667A1	2020-05-07

Foreign References:

KR20110112381A	2011-10-12
KR20170055920A	2017-05-22
US20170044492A1	2017-02-16

Other References:

YUAN YUE, ZHANG JIA, ZHANG HANCHANG, YANG XIURONG: "Silver nanoparticle based label-free colorimetric immunosensor for rapid detection of neurogenin 1", ANALYST, ROYAL SOCIETY OF CHEMISTRY, UK, vol. 137, no. 2, 1 January 2012 (2012-01-01), UK , pages 496 - 501, XP093145097, ISSN: 0003-2654, DOI: 10.1039/C1AN15875A
SONG EE CHAN, PARK CHANHO, SHIN YUNGYEONG, KIM WAN KI, KIM SANG BUM, CHO SEONGMIN: "Neurog1-Derived Peptides RMNE1 and DualPep-Shine Penetrate the Skin and Inhibit Melanin Synthesis by Regulating MITF Transcription", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, MOLECULAR DIVERSITY PRESERVATION INTERNATIONAL (MDPI), BASEL, CH, vol. 24, no. 7, 1 April 2023 (2023-04-01), Basel, CH , pages 6158, XP093145099, ISSN: 1661-6596, DOI: 10.3390/ijms24076158

Attorney, Agent or Firm:

KANG, Seong-Hea (KR)

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