BIALLELIC KNOCKOUT OF ANGPTL3

Title:

BIALLELIC KNOCKOUT OF ANGPTL3

Document Type and Number:

WIPO Patent Application WO/2024/020484

Kind Code:

A3

Abstract:

RNA molecules comprising a guide sequence portion consisting of 17-50 nucleotides and containing 17-22 nucleotides in the sequence set forth in any one of SEQ ID NOs: 1-20347, and compositions, methods, and uses thereof.

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Inventors:

EMMANUEL RAFI (IL)

Application Number:

PCT/US2023/070583

Publication Date:

May 10, 2024

Filing Date:

July 20, 2023

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Assignee:

EMENDOBIO INC (US)

International Classes:

C12N9/22; A61P3/06; C12N15/113; C12N5/071; C12N5/074

Attorney, Agent or Firm:

SZELIGA, Jamaica, P. (975 F Street N.W, Washington DC, US)

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