Title:
AURICULARIA AURICULA POLYSACCHARIDE, USE THEREOF, AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2024/045207
Kind Code:
A1
Abstract:
The present invention relates to the technical field of polysaccharides. Disclosed are an auricularia auricula polysaccharide, use thereof, and a preparation method therefor. Auricularia auricula, after de-fatting, undergoes initial enzymatic hydrolysis under the action of snailase. Further degradation and extraction are performed by means of H2O2 synergistic ultrasound. Then, under the action of a complex enzyme, deep enzymatic hydrolysis is performed, followed by mixed fermentation of Lactobacillus bulgaricus, Streptococcus thermophilus, and Bifidobacterium longum. The resulting fermented Auricularia auricula polysaccharides undergo a phosphorylation reaction under the action of a phosphorylation reagent and are then subjected to deproteinization, decolorization, and chelation with a zinc salt, such that a polysaccharide-zinc complex is obtained, hence obtaining Auricularia auricula polysaccharides. The preparation method is simple, has high extraction efficiency, and yields Auricularia auricula polysaccharides with high purity, good solubility, and enhanced absorbability. These polysaccharides exhibit great physiological activity, including good anti-inflammatory, anti-aging, and blood sugar-lowering effects. The polysaccharides also possess the effects of enhancing immunity, promoting intellectual development, lowering blood lipids, regulating total cholesterol, and effectively increasing beneficial cholesterol, and have wide application prospects.
Inventors:
CHAN SUNSUN (CN)
Application Number:
PCT/CN2022/117433
Publication Date:
March 07, 2024
Filing Date:
September 07, 2022
Export Citation:
Assignee:
BEIJING BEIQING BOYU INFORMATION TECH RESEARCH CO LTD (CN)
International Classes:
A61P3/00; A61P3/06; C08B37/00; C12P19/04; C12P19/14; C12R1/01; C12R1/225; C12R1/46
Domestic Patent References:
| WO2006112036A1 | 2006-10-26 |
Foreign References:
| CN111909285A | 2020-11-10 | |||
| CN113549161A | 2021-10-26 | |||
| CN107177007A | 2017-09-19 | |||
| CN102321186A | 2012-01-18 |
Attorney, Agent or Firm:
CHENGDU YUZHUAZHIYUN INTELLECTUAL PROPERTY AGENCY CO. LTD (CN)
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