Title:
ASYMMETRIC ALLYL FLUORIDE COMPOUND AND METHOD FOR PRODUCING SAME
Document Type and Number:
WIPO Patent Application WO/2024/071281
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide: a novel asymmetric fluorinated allyl compound that can be induced to various bioactive medium-sized molecules, and that has high optical purity; and a method for producing the same. Asymmetric fluorinated allyl compound
Inventors:
XU PENGYU (JP)
YONEYAMA SHIN (JP)
ARIMITSU SATORU (JP)
TOMON DAIKI (JP)
YONEYAMA SHIN (JP)
ARIMITSU SATORU (JP)
TOMON DAIKI (JP)
Application Number:
PCT/JP2023/035346
Publication Date:
April 04, 2024
Filing Date:
September 28, 2023
Export Citation:
Assignee:
SYNCREST INC (JP)
UNIV OF THE RYUKYUS (JP)
UNIV OF THE RYUKYUS (JP)
International Classes:
C07C309/65; C07C49/813; C07D307/46; C07D333/22
Domestic Patent References:
| WO2008090755A1 | 2008-07-31 |
Foreign References:
| JP2005097193A | 2005-04-14 |
Other References:
DAIKI TOMON: "Synthesis of Chiral Tertiary Allylic- and Propargylic Fluorides from Nonaflates of Chiral α-Fluorinated β-Keto Dicarbonyl Compounds", THE JOURNAL OF ORGANIC CHEMISTRY, AMERICAN CHEMICAL SOCIETY, vol. 88, no. 16, 18 August 2023 (2023-08-18), pages 11895 - 11904, XP093154902, ISSN: 0022-3263, DOI: 10.1021/acs.joc.3c01184
ALEXANDRE M. SORLIN: "Advances in Nucleophilic Allylic Fluorination", ACS CATALYSIS, AMERICAN CHEMICAL SOCIETY, US, vol. 10, no. 20, 16 October 2020 (2020-10-16), US , pages 11980 - 12010, XP093154904, ISSN: 2155-5435, DOI: 10.1021/acscatal.0c03493
HAYATO TSUJI: "Stereoselective Synthesis of Trisubstituted E -Iodoalkenes by Indium-Catalyzed syn -Addition of 1,3-Dicarbonyl Compounds to 1-Iodoalkynes", ORGANIC LETTERS, AMERICAN CHEMICAL SOCIETY, US, vol. 10, no. 6, 1 March 2008 (2008-03-01), US , pages 1219 - 1221, XP093154905, ISSN: 1523-7060, DOI: 10.1021/ol800105r
ALEXANDRE M. SORLIN: "Advances in Nucleophilic Allylic Fluorination", ACS CATALYSIS, AMERICAN CHEMICAL SOCIETY, US, vol. 10, no. 20, 16 October 2020 (2020-10-16), US , pages 11980 - 12010, XP093154904, ISSN: 2155-5435, DOI: 10.1021/acscatal.0c03493
HAYATO TSUJI: "Stereoselective Synthesis of Trisubstituted E -Iodoalkenes by Indium-Catalyzed syn -Addition of 1,3-Dicarbonyl Compounds to 1-Iodoalkynes", ORGANIC LETTERS, AMERICAN CHEMICAL SOCIETY, US, vol. 10, no. 6, 1 March 2008 (2008-03-01), US , pages 1219 - 1221, XP093154905, ISSN: 1523-7060, DOI: 10.1021/ol800105r
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
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