Title:
ANTIBODY COMBINATION SPECIFICALLY BINDING TO TRAIL OR FASL, AND BISPECIFIC ANTIBODY
Document Type and Number:
WIPO Patent Application WO/2024/083021
Kind Code:
A1
Abstract:
An antibody specifically binding to TRAIL, a bispecific antibody specifically binding to TRAIL and FasL, and a pharmaceutical composition comprising the antibody specifically binding to TRAIL and an antibody and/or bispecific antibody specifically binding to FasL, and a preparation method therefor and a use thereof.
Inventors:
WANG GUANGFEI (CN)
LI ZHONG (CN)
LI PING (CN)
LI ZHONG (CN)
LI PING (CN)
Application Number:
PCT/CN2023/124152
Publication Date:
April 25, 2024
Filing Date:
October 12, 2023
Export Citation:
Assignee:
BEIJING SOLOBIO GENETECHNOLOGY CO LTD (CN)
International Classes:
C12N5/00; A61K39/395; C07K16/00
Domestic Patent References:
| WO2023138521A1 | 2023-07-27 | |||
| WO2023138522A1 | 2023-07-27 | |||
| WO2016122701A1 | 2016-08-04 | |||
| WO2005016236A2 | 2005-02-24 |
Foreign References:
| CN108290950A | 2018-07-17 | |||
| US20140370019A1 | 2014-12-18 |
Other References:
ROSSIN, A. ET AL.: "TRAIL and FasL Functions in Cancer and Autoimmune Diseases: Towards an Increasing Complexity", CANCERS, vol. 11, 8 May 2019 (2019-05-08), XP093027243, DOI: 10.3390/cancers11050639
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