Title:
AMPHOTERICIN B SEMI-SYNTHETIC DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/274313
Kind Code:
A1
Abstract:
The present invention provides an amphotericin B semi-synthetic derivative, and a preparation method therefor and a use thereof. Specifically, disclosed are a compound having a structure as shown in formula (V), as well as a water-soluble salt, complex and pharmaceutical composition thereof, and plant and animal therapeutic products containing the derivative and a use thereof as antifungal antibiotics. Also disclosed in the present invention is a preparation method for the described compound.
Inventors:
YANG YUSHE (CN)
QIAN ANRAN (CN)
ZHENG YAZHOU (CN)
MA HUIJUN (CN)
QIAN ANRAN (CN)
ZHENG YAZHOU (CN)
MA HUIJUN (CN)
Application Number:
PCT/CN2022/102461
Publication Date:
January 05, 2023
Filing Date:
June 29, 2022
Export Citation:
Assignee:
SHANGHAI INST MATERIA MEDICA CAS (CN)
International Classes:
C07H17/08; A61K31/357; A61P31/10
Domestic Patent References:
WO1999051274A1 | 1999-10-14 | |||
WO2021026520A1 | 2021-02-11 | |||
WO2015190587A1 | 2015-12-17 | |||
WO1993017034A1 | 1993-09-02 | |||
WO2015164289A1 | 2015-10-29 |
Foreign References:
US20150291648A1 | 2015-10-15 | |||
RU2688658C1 | 2019-05-22 |
Attorney, Agent or Firm:
XU&PARTNERS, LLC. (CN)
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