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Title:
AGENT DISPENSING DEVICES, KITS AND RELATED METHODS
Document Type and Number:
WIPO Patent Application WO/2024/086820
Kind Code:
A1
Abstract:
The present disclosure provides on-demand agent dispensing patches, kits and related methods. A flexible patch is configured to contain, and provide on-demand dispensing of, the agent via compression of the patch in a thickness direction thereof. The patch may comprise an adhesive layer to removably couple the patch to a surface; at least one reservoir layer overlying the adhesive layer configured to absorb and retain the agent therein; at least one dispenser layer overlying the at least one reservoir layer comprising a plurality of solid portions and an array of a plurality of openings configured to inhibit evaporation of the agent, and control a flow of the agent therefrom upon the compression of the patch in the thickness direction; and at least one backer layer between the adhesive layer and the at least one reservoir layer being substantially impervious to the agent.

Inventors:
GERBER DANIELLE EVIN (US)
POSITANO ROCK (US)
WHITE ROBERT (US)
Application Number:
PCT/US2023/077460
Publication Date:
April 25, 2024
Filing Date:
October 20, 2023
Export Citation:
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Assignee:
ROXILLA LLC (US)
International Classes:
A61F13/02; A41D13/08; A41D19/015; A61K9/70; A61M35/00; B32B3/26; A61K8/02; A61Q17/00; B32B3/30; B32B5/14
Attorney, Agent or Firm:
ZIEGLER, ESQ., Kristian E. (US)
Download PDF:
Claims:
CLAIMS

What is claimed is:

1. An on-demand liquid or gelatinous agent dispensing kit, comprising: a container containing a volume of a liquid or gelatinous agent; and a flexible patch configured to contain, and provide on-demand dispensing of, the agent via compression of the patch in a thickness direction thereof, the patch comprising: an adhesive layer configured to removably couple the patch to a surface, the adhesive layer defining an inner face of the patch; at least one reservoir layer that is configured to absorb and retain the agent therein, the at least one reservoir layer overlying the adhesive layer in the thickness direction; at least one dispenser layer overlying the at least one reservoir layer in thickness direction comprising a plurality of solid portions and an array of a plurality of openings extending through a thickness thereof, the at least one dispenser layer configured to inhibit evaporation of the agent, and control a flow of the agent from the at least one reservoir layer upon the compression of the patch in the thickness direction, when the agent is contained within the at least one reservoir layer; and at least one backer layer positioned between the adhesive layer and the at least one reservoir layer in the thickness direction, the at least one backer layer being substantially impervious to the agent, wherein the solid portions of the at least one dispenser layer and portions of the at least one reservoir layer underlying the plurality of openings of the at least one dispenser layer define outer face of the patch, and wherein the at least one reservoir layer is void of the agent absorbed therein.

2. The kit according to claim 1, wherein the adhesive is a biocompatible adhesive.

3. The kit according to claim 1, wherein the patch further comprises an inner protective film layer extending over and removably coupled to the adhesive layer.

4. The kit according to claim 1, wherein the patch further comprises an outer protective film layer extending over and removably coupled to the outer face of the patch.

5. The kit according to claim 1 , wherein the patch further comprises a mechanical connector configured to removably attach the patch to an object

6. The kit according to claim 1, wherein the agent is a disinfectant.

7. The kit according to claim 6, wherein the disinfectant is a biocompatible disinfectant.

8. The kit according to claim 6, wherein the disinfectant comprises ethyl, isopropyl, ethanol

(ethyl alcohol), triclosan, triclocarban, benzalkonium chloride, benzethonium chloride or a combination thereof.

9. The kit according to claim 6, wherein the disinfectant comprises ethanol (ethyl alcohol).

10. The kit according to claim 6, wherein the disinfectant comprises a dynamic viscosity within the range of about 4 (Pa s)(m2/s) and about 15 (Pa s)(m2/s) at 20 degrees Celsius.

11. The kit according to claim 1, wherein the agent comprises a medicant or vitamin.

12. The kit according to claim 1, wherein the agent comprises an insecticide.

13. The kit according to claim 1, wherein the agent comprises a fragrance.

14. The kit according to claim 1, wherein the agent comprises a food product.

15. The kit according to claim 1, wherein the agent comprises a cleaning product.

16. The kit according to claim 1 , wherein the agent comprises a paint.

17. The kit according to claim 1, wherein the agent comprises an oil.

18. The kit according to claim 1, wherein the at least one backer layer is substantially impervious to the agent and to air.

19. The kit according to claim 1, wherein the at least one backer layer comprises a solid sheet of material.

20. The kit according to claim 1 , wherein the at least one backer layer comprises a polymer layer.

21. The kit according to claim 20, wherein the at least one backer layer comprises at least one polyethylene layer, polypropylene layer, styrene layer, polyetheretherketone layer, acrylic layer, polyvinyl chloride layer, polyurethane layer, Teflon (Polytetrafluoroethylene) layer, syrlyn layer or a combination thereof.

22. The kit according to claim 1, wherein the at least one dispenser layer comprises a sheet of material that is impervious to the agent.

23. The kit according to claim 22, wherein the at least one dispenser layer comprises a sheet of material that is impervious to air.

24. The kit according to claim 23, wherein the at least one dispenser layer comprises a polymer layer.

25. The kit according to claim 24, wherein the at least one dispenser layer comprises at least one polyethylene layer, polypropylene layer, styrene layer, polyetheretherketone layer, acrylic layer, polyvinyl chloride layer, polyurethane layer, Teflon (Polytetrafluoroethylene) layer, syrlyn layer or a combination thereof.

26. The kit according to claim 22, wherein the solid portions of the at least one dispenser layer comprise within the range of about 10% and about 65% of the total area of the outer face.

27. The kit according to claim 26, wherein the plurality of openings of the at least one dispenser layer comprise an average total area within the range of about 50 mm2 and about 300 mm2 at the outer face.

28. The kit according to claim 26, wherein each of the plurality of openings of the at least one dispenser layer comprise a total area within the range of about .05 mm2 and about .3 mm2 at the outer face.

29. The kit according to claim 1, wherein the patch comprises a total/maximum thickness within the range of about .05 mm and about 3 mm.

30. The kit according to claim 1 , wherein the at least one reservoir layer comprises one or more layers of a fabric, Gore-Tex, gauze, an absorbing gel, a polymer, paper, a foam or a combination thereof.

31. The kit according to claim 30, wherein the at least one reservoir layer comprises one or more layers of polymer fibers, cotton fibers, silicone fibers, hydrogel or a combination thereof.

32. The kit according to claim 31, wherein the at least one reservoir layer comprises a fabric layer of non-woven polymer fibers.

33. The kit according to claim 32, wherein the at least one reservoir layer comprises a layer of non-woven polyethylene and/or polypropylene fibers.

34. The kit according to claim 30, wherein the at least one reservoir layer comprises a natural or synthetic non-woven fabric layer.

35. The kit according to claim 1, wherein the at least one reservoir layer is configured to absorb and retain within the range of about 2 grams and about 50 grams of the agent.

36. The kit according to claim 35, wherein the at least one reservoir layer comprises a detached agent capacity within the range of about 1,000 g/mm2 and about 2,500 g/mm2.

37. The kit according to claim 36, wherein the at least one reservoir layer comprises an agent absorbency rate of at least 5 g/sec for at least the first 5 seconds of water contact.

38. The kit according to claim 1, wherein, when the agent is contained within the at least one reservoir layer, the patch is configured such that a compressive force acting in the thickness direction and applied to the outer surface thereof of at least 1 gram/mmi causes the agent to flow through the plurality of apertures and onto the outer face and/or an object at the outer face.

39. The kit according to claim 1, wherein an inner portion of the patch defines a first maximum thickness, and a peripheral edge portion of the patch extending about the inner portion and defining an outer extent of the patch defines a second thickness that is less than the first thickness.

40. The kit according to claim 1, wherein a peripheral edge portion of the patch defining an outer extent of the patch comprises the at least one reservoir layer, the at least one dispenser layer and the at least one backer layer being bonded together.

41. The kit according to claim 40, wherein the at least one reservoir layer, the at least one dispenser layer and the at least one backer layer are heat, radio-frequency or ultrasonic welded together at the peripheral edge portion of the patch.

42. The kit according to claim 1, wherein, when the agent is contained within the at least one reservoir layer, the patch is configured such that no more than 5 grams of the agent evaporates over 1.5 hours in an ambient environment of non-moving air at 20 degrees Celsius.

43. The kit according to claim 1, wherein the adhesive comprises a biocompatible pressuresensitive adhesive.

44. The kit according to claim 43, wherein the adhesive layer on the outer side of the front face comprises an acrylic-based pressure-sensitive adhesive.

45. The kit according to claim 44, wherein the adhesive layer comprises an adhesive and scrim layer construct.

46. The kit according to claim 1, wherein the container is separate and distinct from the flexible patch.

47. The kit according to claim 1, wherein the container is integrated within, or coupled to, the flexible patch.

48. The kit according to claim 47, wherein the volume of the agent is contained within a manually breakable shell or envelope.

49. The kit according to claim 48, wherein the shell or envelope is contained within the flexible patch, or positioned adjacent to the at least one dispenser layer of the flexible patch.

50. An on-demand agent dispensing pocket device, comprising a flexible agent-impervious pocket comprising a front face, a back face, a bottom portion, a top portion, lateral side portions and an interior cavity between inner sides of the front and back faces, wherein the interior cavity is closed at the bottom and lateral side portions and open or openable at the top portion, and wherein the impervious pocket is impervious to a liquid or gelatinous agent; and at least one reservoir dispenser layer positioned within the interior cavity of the pocket that is configured to absorb and retain a liquid or gelatinous agent therein, and control a flow of the agent from the at least one reservoir layer upon compression of the at least one reservoir layer when the agent is retained therein.

51. The device of claim 50, wherein the device further comprises an attachment mechanism on the outer side of the back face that is configured to couple the device to an object.

52. The device of claim 51, wherein the attachment mechanism is configured to removably couple the device to an object.

53. The device of claim 52, wherein the attachment mechanism comprises an adhesive layer overlying at least a portion of the outer side of the back face configured to removably couple the device to a surface.

54. The device of claim 53, wherein the adhesive layer comprises a biocompatible adhesive.

55. The device of claim 54, wherein the adhesive layer comprises an acrylic-based pressuresensitive adhesive.

56. The device of claim 55, wherein the adhesive layer comprises an adhesive and scrim layer construct that is coupled to the outer side of the back face via the adhesive.

57. The device of claim 56, wherein the device further comprises a removable back liner layer extending over the adhesive layer to temporarily cover the adhesive layer.

58. The device of claim 52, wherein the attachment mechanism comprises a clip or flap member that extends from the back face.

59. The device of claim 51 , wherein the device further comprises an attachment mechanism on the outer side of the front face that is configured to couple the device to an object.

60. The device of claim 59, wherein the attachment mechanism on the outer side of the front face is configured to removably couple the device to an object.

61. The device of claim 60, wherein the attachment mechanism on the outer side of the front face comprises an adhesive layer overlying at least a portion of the outer side configured to removably couple the device to a surface.

62. The device of claim 61, wherein the adhesive layer on the outer side of the front face comprises a biocompatible adhesive.

63. The device of claim 62, wherein the adhesive layer on the outer side of the front face comprises an acrylic-based pressure-sensitive adhesive.

64. The device of claim 63, wherein the adhesive layer on the outer side of the front face comprises an adhesive and scrim layer construct that is coupled to the outer side of the front face via the adhesive.

65. The device of claim 64, wherein the device further comprises a removable front liner layer extending over the adhesive layer to temporarily cover the adhesive layer on the outer side of the front face.

66. The device of claim 60, wherein the attachment mechanism on the outer side of the front face comprises a clip or flap member that extends from the back face.

67. The device of claim 50, wherein the at least one reservoir layer contains a volume of the agent absorbed and retained therein.

68. The device of claim 50, wherein the at least one reservoir layer is void of the agent, and wherein the device further comprises container of the agent for selectively applying the agent to an inner side of the at least one reservoir layer.

69. The device of claim 50, wherein the agent comprises a sanitizing disinfectant.

70. The device of claim 69, wherein the disinfectant is a biocompatible disinfectant.

71. The device of claim 70, wherein the disinfectant comprises ethyl, isopropyl, ethanol (ethyl alcohol), triclosan, triclocarban, benzalkonium chloride, benzethonium chloride or a combination thereof.

72. The device of claim 71, wherein the disinfectant comprises ethanol (ethyl alcohol).

73. The device of claim 50, wherein the agent comprises a medicant or vitamin.

74. The device of claim 50, wherein the agent comprises an insecticide.

75. The device of claim 50, wherein the agent comprises a fragrance.

76. The device of claim 50, wherein the agent comprises a food product.

77. The device of claim 50, wherein the agent comprises a cleaning product.

78. The device of claim 50, wherein the agent comprises a paint.

79. The device of claim 50, wherein the agent comprises an oil.

80. The device of claim 50, wherein the agent comprises a dynamic viscosity within the range of about 4 (Pa s)(m2/s) and about 15 (Pa s)(m2/s) at 20 degrees Celsius.

81. The device of claim 50, wherein the least one reservoir dispenser layer comprises at least one dispenser layer comprising a plurality of solid portions and an array of a plurality of openings extending through a thickness thereof, the at least one dispenser layer configured to inhibit evaporation of the agent, and control a flow of the agent from the least one reservoir dispenser layer upon the compression of the least one reservoir dispenser layer in a thickness direction when the agent is contained within the least one reservoir dispenser layer.

82. The device of claim 81, wherein the at least one dispenser layer defines an inner most surface of the least one reservoir dispenser layer and is exposed to the internal cavity.

83. The device of claim 82, wherein the at least one dispenser layer comprises a sheet of material that is impervious to the agent.

84. The device of claim 83, wherein the at least one dispenser layer comprises a sheet of material that is impervious to air.

85. The device of claim 84, wherein the at least one dispenser layer comprises a polymer layer.

86. The device of claim 85, wherein the at least one dispenser layer comprises at least one polyethylene layer, polypropylene layer, styrene layer, polyetheretherketone layer, acrylic layer, polyvinyl chloride layer, polyurethane layer, Teflon (Polytetrafluoroethylene) layer, syrlyn layer or a combination thereof.

87. The device of claim 86, wherein the solid portions of the at least one dispenser layer comprise within the range of about 10% and about 65% of the total area of the outer face.

88. The device of claim 87, wherein the plurality of openings of the at least one dispenser layer comprise an average total area within the range of about 50 mm2 and about 300 mm2 at the outer face.

89. The device of claim 88, wherein each of the plurality of openings of the at least one dispenser layer comprise a total area within the range of about .05 mm2 and about .3 mm2 at the outer face.

90. The device of claim 89, wherein the least one reservoir dispenser layer comprises at least one reservoir layer that is configured to absorb and retain the agent therein.

91. The device of claim 90, wherein the at least one reservoir layer underlies the at least one dispenser layer.

92. The device of claim 90, wherein the at least one reservoir layer comprises one or more layers of a fabric, Gore-Tex, gauze, an absorbing gel, a polymer, paper, a foam or a combination thereof.

93. The device of claim 90, wherein the at least one reservoir layer comprises one or more layers of polymer fibers, cotton fibers, silicone fibers, hydrogel or a combination thereof.

94. The device of claim 90, wherein the at least one reservoir layer comprises a fabric layer of non-woven polymer fibers.

95. The device of claim 90, wherein the at least one reservoir layer comprises a layer of nonwoven polyethylene and/or polypropylene fibers.

96. The device of claim 90, wherein the at least one reservoir layer comprises a natural or synthetic non-woven fabric layer.

97. The device of claim 90, wherein the at least one reservoir layer is configured to absorb and retain within the range of about 2 grams and about 50 grams of the agent.

98. The device of claim 97, wherein the at least one reservoir layer comprises a detached agent capacity within the range of about 1,000 g/mm2 and about 2,500 g/mm2.

99. The device of claim 98, wherein the at least one reservoir layer comprises an agent absorbency rate of at least 5 g/sec for at least the first 5 seconds of water contact.

100. The device of claim 99, wherein the at least one reservoir dispenser layer is configured such that a compressive force acting in the thickness direction and applied to an exposed inner surface thereof of at least 1 gram/mm2 causes the agent to flow therefrom and onto the exposed inner surface.

101. The device of claim 90, wherein the least one reservoir dispenser layer comprises at least one backer layer underlying at least one reservoir layer, the at least one backer layer being substantially impervious to the agent.

102. The device of claim 101, wherein the at least one backer layer is substantially impervious to the agent and to air.

103. The device of claim 102, wherein the at least one backer layer comprises a solid sheet of material.

104. The device of claim 103, wherein the at least one backer layer comprises a polymer layer.

105. The device of claim 104, wherein the at least one backer layer comprises at least one polyethylene layer, polypropylene layer, styrene layer, polyetheretherketone layer, acrylic layer, polyvinyl chloride layer, polyurethane layer, Teflon (Polytetrafluoroethylene) layer, syrlyn layer or a combination thereof.

106. The device of claim 60, wherein the front face and/or the back face of the pocket is substantially impervious to the agent.

107. The device of claim 106, wherein the front face and/or the back face of the pocket is substantially impervious to the agent and to air.

108. The device of claim 107, wherein the front face and/or the back face of the pocket comprises a solid sheet of material.

109. The device of claim 108, wherein the front face and/or the back face of the pocket comprises a polymer layer.

110. The device of claim 109, wherein the front face and/or the back face of the pocket comprises at least one polyethylene layer, polypropylene layer, styrene layer, polyetheretherketone layer, acrylic layer, polyvinyl chloride layer, polyurethane layer, Teflon (Polytetrafluoroethylene) layer, syrlyn layer or a combination thereof.

111. The device of claim 50, wherein the at least one reservoir dispenser layer comprises a total thickness within the range of about .05 mm and about 3 mm.

112. The device of claim 50, wherein an inner portion of the at least one reservoir dispenser layer defines a first maximum thickness, and a peripheral edge portion of the at least one reservoir dispenser layer extending about the inner portion and defining an outer extent of the at least one reservoir dispenser layer defines a second thickness that is less than the first thickness.

113. The device of claim 50, wherein the at least one reservoir dispenser layer comprises at least one dispenser layer and at least one reservoir layer bonded together.

114. The device of claim 113, wherein the at least one dispenser layer overlies the at least one reservoir layer, and the at least one reservoir layer is bonded to the inner face or outer face.

115. The device of claim 1 14, wherein the at least one reservoir layer, the at least one dispenser layer and the inner face or outer face are heat, radio-frequency or ultrasonic welded together at the peripheral edge portion of the patch.

116. The device of claim 115, wherein, when the agent is contained within the at least one reservoir layer, the device is configured such that no more than 5 grams of the agent evaporates over 1.5 hours in an ambient environment of non-moving air at 20 degrees Celsius.

117. The device of claim 115, wherein the at least one reservoir dispenser layer comprises a plurality of sublayers coupled together.

118. The device of claim 50, further comprising a volume of the agent.

119. The device of claim 118, wherein the volume of the agent is absorbed within the at least one reservoir dispenser layer.

120. The device of claim 118, wherein the volume of the agent is contained within a manually breakable shell or envelope.

121. The device of claim 120, wherein the shell or envelope is contained within, or positioned to, the at least one reservoir dispenser layer.

122. The device of claim 121, wherein the device is configured as an on-demand agent dispensing pocket patch.

Description:
AGENT DISPENSING DEVICES, KTTS AND RELATED METHODS

CROSS-REFERENCE TO RELATED APPLICATION

[001] This application perfects and claims priority benefit of U.S. Provisional Patent Application No. 63/418,041, filed on October 21, 2022, and entitled Agent Dispensing Devices, Kits and Related Methods, the entirety of which is hereby expressively incorporated herein by reference.

FIELD OF THE DISCLOSURE

[002] The present disclosure relates generally to on-demand agent (e.g., disinfectant) dispensing devices, kits and related methods. More specifically, the present disclosure relates to agent (e.g., disinfectant) dispensing adhesive patches that are configured to be removably affixed to a user or surface, and provide on-demand dispensing of an agent over an extended period of time.

BACKGROUND

[003] There is substantial evidence that pathogens (i.e., disease-causing microorganisms, such as various viruses, bacteria, fungus, and parasites) can be transmitted from a first person to a second person via the first person physically touching the second person (e.g., via a handshake, hug, kiss, etc.) or the first person physically touching or otherwise infecting (e.g., via one or more respiratory function, a pet, etc.) a communal object (e.g., a surface, object, knob, button, handle, hand rail, key, screen, money, card, etc.) that is subsequently physically touched by the second person. Most commonly, pathogens are passed between people via physical touch through their hands - a pathogen becomes present one the first person's hand, and is transferred to the second person's hand via physical contact with the first person's hand or with an object that that first person's hand previously contacted or that the first person infected via one or more respiratory functions (e.g., breathing, coughing, sneezing, talking, etc.) or by a third party (e.g., via another person, a pet, etc.). Thus, not only can a person become infected by a pathogen by touching their eyes, nose or mouth with their hand (or with an object that that they touched with their hand), they can pass a pathogen to one or more other people by touching a communal object.

[004] Because many infectious pathogens (such as viruses, for example the common cold) are contracted and spread to others via physical touching primarily by the hands, conventional medical wisdom teaches that the best way to prevent contraction and transmission of most pathogens (and resulting infections) is by thoroughly and frequently disinfecting/sanitizing/sterilizing one's hands throughout the day by washing their hands with soap and water. In addition to and/or in place of washing one's hands, a topical disinfecting/sanitizing/sterilizing agent such as, for example, a denatured alcohol, an antibacterial hand gel, or an anti-bacterial hand lotion to further protect the hands may be utilized.

[005] Although these measures will help to control the spread of many pathogens residing on the skin, they are ineffective if not performed routinely and methodically. Unfortunately, many individuals do not have immediate access to facilities to adequately wash their hands with soap and water, and/or to a topical disinfectant. For example, many liquid and/or gel topical disinfectants are packaged in a bottle configured with a spray or squeeze dispenser. These bottled disinfectants requires the bottle to be carried by an individual, taken out when disinfectant is needed, and manually opened and applied (most typically to their hand(s)). As another example, sanitizing wipes or towelettes that contained a liquid topical disinfectant are sometimes utilized, but include the same disadvantages as bottled disinfectants. Accordingly, liquid and/or gelatinous disinfectants are not readily immediately available over an extended period of time. As such, they are often not utilized as often as they should and/or would be compared to if they were easily available on-demand.

[006] Hand sanitizer stations which contain a relatively larger reservoir of a topical disinfectant are also commonplace. Such stations are typically only found in high population spaces, areas where pathogens are more commonly found and/or areas where vulnerable people are located. Because of their scarcity, sanitizer stations thereby fail to protect users from the constant barrage of surfaces and 3rd party individuals that people come into contact with on a daily basis.

[007] It is further noted that other liquid and/or gelatinous agents and materials that people wish to receive periodic doses of (or periodically dispense) suffer from the same deficiencies noted above with respect to disinfectant/sanitizer.

[008] It is thereby an object of the on-demand agent dispensing devices and kits, and related methods, provided herein to addresses one or more of the aforementioned problems of the prior art. The on-demand agent dispensing devices, kits and related methods disclosed herein solve the above noted deficiencies of current agent dispensing devices and related methods by, inter alia, providing a removably affixable device/patch that provides on-demand access (via dispensing doses or amounts thereof) of a liquid and/or gelatinous agent (e.g., a disinfectant) to a user over an extended period of time.

SUMMARY

[009] On-demand agent (e.g., disinfectant) dispensing devices (and disinfecting methods utilizing such devices) that can be removably affixed to a user or surface that provide quick and easy access to the agent over an extended period of time are disclosed herein. The present disclosure provides such devices and kits, and related methods, for dispensing the agent onto a user's body (e.g., the skin of a user's hand) via an adhesive patch. In embodiments wherein the agent is a sanitizer/disinfectant liquid or gel, the devices, kits and methods provide for manual dispensing of the sanitizer/disinfectant to a user (e.g., a user hand), and potential transfer of the sanitizer/disinfectant to another portion of the user, another person or an inanimate object. Such on-demand disinfectant dispensing devices, kits and methods are thereby able to provide an on- demand sanitizer/disinfectant to one or more people and/or surfaces.

[010] The on-demand agent dispensing devices and kits provide simple, cost effective solutions to selectively provide access to, and dispensing of, a liquid or gelatinous agent, such as but not limited to alcohol-based sanitizer/disinfectant liquids or gels.

[OH] The devices are self-contained, are void of containers that need to be carried and opened, retain the agent within the device (i.e., a no spill solution), and do not necessitate pouring or spraying for dispensing of the agent. In some embodiments, the on-demand agent dispensing devices and kits may be configured to with an adhesive patch that is configured to be removably affixed to a user, such as to the user's skin or the user's clothing (or any other inanimate object carried or worn by the user). In some embodiments, the on-demand agent dispensing patches are wearable, and may be configured to be removably affixed to an active point/portion of contact of the user that would benefit from having the agent at that location, such as sanitizer/disinfectant on the inside of a user's hand (e.g., on the palm and/or fingers). In some embodiments, the on- demand agent dispensing wearable device may be configured to be removably affixed to a passive portion of the user's skin (or an object worn/carried by the user) (or on an inanimate object remote from the user) that is spaced from the point/portion of contact of the user, to allow for selective application of the agent on the portion of contact of the user from the device. For example, a passive on-demand disinfectant dispensing wearable patch device may be configured to be removably affixed to the back of a user's hand (or a user's forearm) or on/in clothing worn by the user, and the user may wipe their finger(s)/hand on/over the device to apply the disinfectant thereto (and thereby disinfect their finger(s)/hand). In such a passive disinfecting embodiment, the on-demand disinfectant dispensing wearable device provides quick and discrete on-demand access to a sanitizer/disinfectant where swiping/contacting the device disinfects a person's point/portion of contact (e.g., their hand(s) or other skin surface).

[012] The on-demand agent dispensing device embodiments may be configured to be applied to an active or passive surface portion of a user (or an object) to disinfect it, and, potentially, passes it on to a third party that subsequently touches the surface portion (i.e., pays it forward). In this way, the on-demand disinfectant dispensing devices can provide a level of disinfecting of safety to the user, with the additional benefit of protecting others that may touch a common surface/object. Communal touchpoints can thus be sanitized and provide an integral part to the health and wellbeing of a community as a whole.

[013] The on-demand agent dispensing devices of the present disclosure are configured as an on-demand long lasting liquid/gelatinous agent supply and dispensing patch. The on-demand agent supply and dispensing patch includes an adhesive layer or portion that is configured to removably attach to a user or an inanimate object. The on-demand agent supply and dispensing patch also includes at least one reservoir layer that is configured to absorb and retain the liquid/gelatinous agent therein, and at least one metered/controlled release or dispensing layer that overlies at least a portion of the at least one reservoir layer. The at least one metered/controlled release layer is configured to control the release (e.g., volume dispensed and pressure needed to dispense) of the agent at/to an outer surface of the patch (and thereby to a user) from the at least one reservoir layer, and mitigate/inhibit evaporation of the liquid/gelatinous agent in the at least one reservoir layer. In some embodiments, the on-demand agent supply and dispensing patch may include at least one backer layer positioned between the adhesive layer and the at least one reservoir layer that is impervious to the liquid/gelatinous agent such that the liquid/gelatinous agent is prevented from interacting with the adhesive of the adhesive layer, and is thereby retained above the at least one backer layer. In some embodiments, the at least one reservoir layer, the at least one metered/controlled dispensing layer and the at least one backer layer are heat welded or sealed together about the periphery of the patch, and form a peripheral barrier or border about an interior area or portion of the patch that substantially retains the agent within the at least one reservoir layer in the interior area of the patch until it is selectively dispended by a user via pressure applied to the outer surface of the patch such that the at least one reservoir layer is compressed (in a thickness direction thereof).

[014] In one aspect, the present disclosure provides an on-demand liquid or gelatinous agent dispensing kit, comprising: a container containing a volume of a liquid or gelatinous agent; and a flexible patch configured to contain, and provide on-demand dispensing of, the agent via compression of the patch in a thickness direction thereof. The patch comprises: an adhesive layer configured to removably couple the patch to a surface, the adhesive layer defining an inner face of the patch; at least one reservoir layer that is configured to absorb and retain the agent therein, the at least one reservoir layer overlying the adhesive layer in the thickness direction; at least one dispenser layer overlying the at least one reservoir layer in thickness direction comprising a plurality of solid portions and an array of a plurality of openings extending through a thickness thereof, the at least one dispenser layer configured to inhibit evaporation of the agent, and control a flow of the agent from the at least one reservoir layer upon the compression of the patch in the thickness direction, when the agent is contained within the at least one reservoir layer; and at least one backer layer positioned between the adhesive layer and the at least one reservoir layer in the thickness direction, the at least one backer layer being substantially impervious to the agent. The solid portions of the at least one dispenser layer and portions of the at least one reservoir layer underlying the plurality of openings of the at least one dispenser layer define outer face of the patch. The at least one reservoir layer is void of the agent absorbed therein.

[015] In some embodiments, the adhesive is a biocompatible adhesive. In some embodiments, the patch further comprises an inner protective film layer extending over and removably coupled to the adhesive layer. In some embodiments, the patch further comprises an outer protective film layer extending over and removably coupled to the outer face of the patch. In some embodiments, the patch further comprises a mechanical connector configured to removably attach the patch to an object.

[016] In some embodiments, the agent is a disinfectant. In some such embodiments, the disinfectant is a biocompatible disinfectant. In some embodiments, the disinfectant comprises ethyl, isopropyl, ethanol (ethyl alcohol), triclosan, triclocarban, benzalkonium chloride, benzethonium chloride or a combination thereof. In some embodiments, the disinfectant comprises ethanol (ethyl alcohol). In some embodiments, the disinfectant comprises a dynamic viscosity within the range of about 4 (Pa s)(m2/s) and about 15 (Pa s)(m2/s) at 20 degrees Celsius.

[017] In some embodiments, the agent comprises a medicant or vitamin. In some embodiments, the agent comprises an insecticide. In some embodiments, the agent comprises a fragrance. In some embodiments, the agent comprises a food product. In some embodiments, the agent comprises a cleaning product. In some embodiments, the agent comprises a paint. In some embodiments, the agent comprises an oil.

[018] In some embodiments, the at least one backer layer is substantially impervious to the agent and to air. In some embodiments, the at least one backer layer comprises a solid sheet of material. In some embodiments, the at least one backer layer comprises a polymer layer. In some embodiments, the at least one backer layer comprises at least one polyethylene layer, polypropylene layer, styrene layer, polyetheretherketone layer, acrylic layer, polyvinyl chloride layer, polyurethane layer, Teflon (Polytetrafluoroethylene) layer, syrlyn layer or a combination thereof.

[019] In some embodiments, the at least one dispenser layer comprises a sheet of material that is impervious to the agent. In some embodiments, the at least one dispenser layer comprises a sheet of material that is impervious to air. In some embodiments, the at least one dispenser layer comprises a polymer layer. In some embodiments, the at least one dispenser layer comprises at least one polyethylene layer, polypropylene layer, styrene layer, polyetheretherketone layer, acrylic layer, polyvinyl chloride layer, polyurethane layer, Teflon (Polytetrafluoroethylene) layer, syrlyn layer or a combination thereof. In some embodiments, the solid portions of the at least one dispenser layer comprise within the range of about 10% and about 65% of the total area of the outer face. In some embodiments, the plurality of openings of the at least one dispenser layer comprise an average total area within the range of about 50 mm 2 and about 300 mm 2 at the outer face. In some embodiments, each of the plurality of openings of the at least one dispenser layer comprise a total area within the range of about .05 mm 2 and about .3 mm 2 at the outer face.

[020] In some embodiments, the at least one reservoir layer comprises one or more layers of a fabric, Gore-Tex, gauze, an absorbing gel, a polymer, paper, a foam or a combination thereof. In some embodiments, the at least one reservoir layer comprises one or more layers of polymer fibers, cotton fibers, silicone fibers, hydrogel or a combination thereof Tn some embodiments, the at least one reservoir layer comprises a fabric layer of non-woven polymer fibers. In some embodiments, the at least one reservoir layer comprises a layer of non-woven polyethylene and/or polypropylene fibers. In some embodiments, the at least one reservoir layer comprises a natural or synthetic non-woven fabric layer. In some embodiments, the at least one reservoir layer is configured to absorb and retain within the range of about 2 grams and about 50 grams of the agent. In some embodiments, the at least one reservoir layer comprises a detached agent capacity within the range of about 1,000 g/mm 2 and about 2,500 g/mm 2 . In some embodiments, the at least one reservoir layer comprises an agent absorbency rate of at least 5 g/sec for at least the first 5 seconds of water contact. In some embodiments, when the agent is contained within the at least one reservoir layer, the patch is configured such that a compressive force acting in the thickness direction and applied to the outer surface thereof of at least 1 gram/mm 2 causes the agent to flow through the plurality of apertures and onto the outer face and/or an object at the outer face.

[021] In some embodiments, the, when the agent is contained within the at least one reservoir layer, the patch is configured such that no more than 5 grams of the agent evaporates over 1.5 hours in an ambient environment of non-moving air at 20 degrees Celsius.

[022] In some embodiments, the patch comprises a total thickness within the range of about .05 mm and about 3 mm. In some embodiments, an inner portion of the patch defines a first maximum thickness, and a peripheral edge portion of the patch extending about the inner portion and defining an outer extent of the patch defines a second thickness that is less than the first thickness. In some embodiments, a peripheral edge portion of the patch defining an outer extent of the patch comprises the at least one reservoir layer, the at least one dispenser layer and the at least one backer layer being bonded together. In some embodiments, the at least one reservoir layer, the at least one dispenser layer and the at least one backer layer are heat, radio-frequency or ultrasonic welded together at the peripheral edge portion of the patch.

[023] In some embodiments, the adhesive comprises a biocompatible adhesive. In some embodiments, the adhesive layer on the outer side of the front face comprises an acrylic-based pressure-sensitive adhesive. In some embodiments, the adhesive layer comprises an adhesive and scrim layer construct. [024] In some embodiments, the container is separate and distinct from the flexible patch. In some embodiments, the container is integrated within, or coupled to, the flexible patch. In some embodiments, the volume of the agent is contained within a manually breakable shell or envelope. In some embodiments, the shell or envelope is contained within the flexible patch, or positioned adjacent to the at least one dispenser layer of the flexible patch.

[025] In another aspect, the present disclosure provides an on-demand agent dispensing pocket device. The device comprises: a flexible agent-impervious pocket comprising a front face, a back face, a bottom portion, a top portion, lateral side portions and an interior cavity between inner sides of the front and back faces, wherein the interior cavity is closed at the bottom and lateral side portions and open or openable at the top portion, and wherein the impervious pocket is impervious to a liquid or gelatinous agent; and at least one reservoir dispenser layer positioned within the interior cavity of the pocket that is configured to absorb and retain a liquid or gelatinous agent therein, and control a flow of the agent from the at least one reservoir layer upon compression of the at least one reservoir layer when the agent is retained therein.

[026] In some embodiments, the device further comprises an attachment mechanism on the outer side of the back face that is configured to couple the device to an object. In some embodiments, the attachment mechanism is configured to removably couple the device to an object. In some embodiments, the attachment mechanism comprises a clip or flap member that extends from the back face.

[027] In some embodiments, the attachment mechanism comprises an adhesive layer overlying at least a portion of the outer side of the back face configured to removably couple the device to a surface. In some embodiments, the adhesive layer comprises a biocompatible adhesive. In some embodiments, the adhesive layer comprises an acrylic-based pressure-sensitive adhesive.

In some embodiments, the adhesive layer comprises an adhesive and scrim layer construct that is coupled to the outer side of the back face via the adhesive. In some embodiments, the device further comprises a removable back liner layer extending over the adhesive layer to temporarily cover the adhesive layer.

[028] In some embodiments, the device further comprises an attachment mechanism on the outer side of the front face that is configured to couple the device to an object. In some embodiments, the attachment mechanism on the outer side of the front face is configured to removably couple the device to an object. Tn some embodiments, the attachment mechanism on the outer side of the front face comprises a clip or flap member that extends from the back face.

[029] In some embodiments, the attachment mechanism on the outer side of the front face comprises an adhesive layer overlying at least a portion of the outer side configured to removably couple the device to a surface. In some embodiments, the adhesive layer on the outer side of the front face comprises a biocompatible adhesive. In some embodiments, the adhesive layer on the outer side of the front face comprises an acrylic-based pressure-sensitive adhesive. In some embodiments, the adhesive layer on the outer side of the front face comprises an adhesive and scrim layer construct that is coupled to the outer side of the front face via the adhesive. In some embodiments, the device further comprises a removable front liner layer extending over the adhesive layer to temporarily cover the adhesive layer on the outer side of the front face.

[030] In some embodiments, the at least one reservoir layer contains a volume of the agent absorbed and retained therein. In some embodiments, the at least one reservoir layer is void of the agent, and wherein the device further comprises container of the agent for selectively applying the agent to an inner side of the at least one reservoir layer. In some embodiments, when the agent is contained within the at least one reservoir layer, the device is configured such that no more than 5 grams of the agent evaporates over 1.5 hours in an ambient environment of non-moving air at 20 degrees Celsius.

[031] In some embodiments, the agent comprises a sanitizing disinfectant. In some embodiments, the disinfectant is a biocompatible disinfectant. In some embodiments, the disinfectant comprises ethyl, isopropyl, ethanol (ethyl alcohol), triclosan, triclocarban, benzalkonium chloride, benzethonium chloride or a combination thereof. In some embodiments, the disinfectant comprises ethanol (ethyl alcohol).

[032] In some embodiments, the agent comprises a medicant or vitamin. In some embodiments, the agent comprises an insecticide. In some embodiments, the agent comprises a fragrance. In some embodiments, the agent comprises a food product. In some embodiments, the agent comprises a cleaning product. In some embodiments, the agent comprises a paint. In some embodiments, the agent comprises an oil. In some embodiments, the agent comprises a dynamic viscosity within the range of about 4 (Pa s)(m2/s) and about 15 (Pa s)(m2/s) at 20 degrees Celsius. [033] In some embodiments, the least one reservoir dispenser layer comprises at least one dispenser layer comprising a plurality of solid portions and an array of a plurality of openings extending through a thickness thereof, the at least one dispenser layer configured to inhibit evaporation of the agent, and control a flow of the agent from the least one reservoir dispenser layer upon the compression of the least one reservoir dispenser layer in a thickness direction when the agent is contained within the least one reservoir dispenser layer.

[034] In some embodiments, the at least one dispenser layer defines an inner most surface of the least one reservoir dispenser layer and is exposed to the internal cavity. In some embodiments, the at least one dispenser layer comprises a sheet of material that is impervious to the agent. In some embodiments, the at least one dispenser layer comprises a sheet of material that is impervious to air. In some embodiments, the at least one dispenser layer comprises a polymer layer. In some embodiments, the at least one dispenser layer comprises at least one polyethylene layer, polypropylene layer, styrene layer, polyetheretherketone layer, acrylic layer, polyvinyl chloride layer, polyurethane layer, Teflon (Polytetrafluoroethylene) layer, syrlyn layer or a combination thereof. In some embodiments, the solid portions of the at least one dispenser layer comprise within the range of about 10% and about 65% of the total area of the outer face. In some embodiments, the plurality of openings of the at least one dispenser layer comprise an average total area within the range of about 50 mm 2 and about 300 mm 2 at the outer face. In some embodiments, each of the plurality of openings of the at least one dispenser layer comprise a total area within the range of about .05 mm 2 and about .3 mm 2 at the outer face.

[035] In some embodiments, the least one reservoir dispenser layer comprises at least one reservoir layer that is configured to absorb and retain the agent therein. In some embodiments, the at least one reservoir layer underlies the at least one dispenser layer.

[036] In some embodiments, the at least one reservoir layer comprises one or more layers of a fabric, Gore-Tex, gauze, an absorbing gel, a polymer, paper, a foam or a combination thereof. In some embodiments, the at least one reservoir layer comprises one or more layers of polymer fibers, cotton fibers, silicone fibers, hydrogel or a combination thereof. In some embodiments, the at least one reservoir layer comprises a fabric layer of non-woven polymer fibers. In some embodiments, the at least one reservoir layer comprises a layer of non-woven polyethylene and/or polypropylene fibers. In some embodiments, the at least one reservoir layer comprises a natural or synthetic non-woven fabric layer. [037] In some embodiments, the at least one reservoir layer is configured to absorb and retain within the range of about 2 grams and about 50 grams of the agent. In some embodiments, the at least one reservoir layer comprises a detached agent capacity within the range of about 1,000 g/mm 2 and about 2,500 g/mm 2 . In some embodiments, the at least one reservoir layer comprises an agent absorbency rate of at least 5 g/sec for at least the first 5 seconds of water contact. In some embodiments, the at least one reservoir dispenser layer is configured such that a compressive force acting in the thickness direction and applied to an exposed inner surface thereof of at least 1 gram/mm 2 causes the agent to flow therefrom and onto the exposed inner surface.

[038] In some embodiments, the least one reservoir dispenser layer comprises at least one backer layer underlying at least one reservoir layer, the at least one backer layer being substantially impervious to the agent. In some embodiments, the at least one backer layer is substantially impervious to the agent and to air. In some embodiments, the at least one backer layer comprises a solid sheet of material. In some embodiments, the at least one backer layer comprises a polymer layer. In some embodiments, the at least one backer layer comprises at least one polyethylene layer, polypropylene layer, styrene layer, polyetheretherketone layer, acrylic layer, polyvinyl chloride layer, polyurethane layer, Teflon (Polytetrafluoroethylene) layer, syrlyn layer or a combination thereof.

[039] In some embodiments, the front face and/or the back face of the pocket is substantially impervious to the agent. In some embodiments, the front face and/or the back face of the pocket is substantially impervious to the agent and to air. In some embodiments, the front face and/or the back face of the pocket comprises a solid sheet of material. In some embodiments, the front face and/or the back face of the pocket comprises a polymer layer. In some embodiments, the front face and/or the back face of the pocket comprises at least one polyethylene layer, polypropylene layer, styrene layer, polyetheretherketone layer, acrylic layer, polyvinyl chloride layer, polyurethane layer, Teflon (Polytetrafluoroethylene) layer, syrlyn layer or a combination thereof.

[040] In some embodiments, the at least one reservoir dispenser layer comprises a total thickness within the range of about .05 mm and about 3 mm. In some embodiments, an inner portion of the at least one reservoir dispenser layer defines a first maximum thickness, and a peripheral edge portion of the at least one reservoir dispenser layer extending about the inner portion and defining an outer extent of the at least one reservoir dispenser layer defines a second thickness that is less than the first thickness.

[041] In some embodiments, the at least one reservoir dispenser layer comprises at least one dispenser layer and at least one reservoir layer bonded together. In some embodiments, the at least one dispenser layer overlies the at least one reservoir layer, and the at least one reservoir layer is bonded to the inner face or outer face. In some embodiments, the at least one reservoir layer, the at least one dispenser layer and the inner face or outer face are heat, radio-frequency or ultrasonic welded together at the peripheral edge portion of the patch. In some embodiments, the at least one reservoir dispenser layer comprises a plurality of sublayers coupled together.

[042] In some embodiments, further comprising a volume of the agent. In some embodiments, the volume of the agent is absorbed within the at least one reservoir dispenser layer. In some embodiments, the volume of the agent is contained within a manually breakable shell or envelope. In some embodiments, the shell or envelope is contained within, or positioned to, the at least one reservoir dispenser layer. In some embodiments, the device is configured as an on- demand agent dispensing pocket patch.

[043] It should be appreciated that all combinations of the foregoing concepts and additional concepts discussed in greater detail below (provided such concepts are not mutually inconsistent) are contemplated as being part of the inventive subject matter disclosed herein and may be used to achieve the benefits and advantages described herein.

[044] These and other objects, features and advantages of this disclosure will become apparent from the following detailed description of the various aspects of the disclosure taken in conjunction with the accompanying drawings.

BRIEF DESCRIPTION OF THE DRAWINGS

[045] These and other features, aspects, and advantages of the present disclosure will become better understood when the following detailed description is read with reference to the accompanying drawings. It should be understood that at least some of the drawings are not necessarily to scale (but at least some of the drawings may be drawn to scale). In certain figures, details that are not necessary for an understanding of the disclosure or that render other details difficult to perceive may have been omitted. It should be understood, of course, that the disclosure is not necessarily limited to the particular embodiments illustrated in the figures. Like reference numerals are utilized throughout the figures to represent like aspects illustrated in the drawings, wherein:

[046] FIG. 1 illustrates a top perspective partial-exploded view of an on-demand agent dispensing patch according to one embodiment of the present disclosure.

[047] FIG. 2 illustrates a top perspective exploded view of an on-demand agent dispensing patch according to one embodiment of the present disclosure.

[048] FIG. 3 illustrates another top perspective exploded view of an on-demand agent dispensing patch according to one embodiment of the present disclosure.

[049] FIG. 4 illustrates a top perspective view of an on-demand agent dispensing patch according to one embodiment of the present disclosure.

[050] FIG. 5 illustrates a top view of the on-demand agent dispensing patch of FIG. 4 according to one embodiment of the present disclosure.

[051] FIG. 6 illustrates a side view of the on-demand agent dispensing patch of FIG. 4 according to one embodiment of the present disclosure.

[052] FIG. 7 illustrates a plurality of the on-demand agent dispensing patch of FIG. 4 provided on a support member according to one embodiment of the present disclosure.

[053] FIG. 8 illustrates a top perspective view of a kit comprising a plurality of on-demand agent dispensing patches and a container of a volume of an agent according to one embodiment of the present disclosure.

[054] FIG. 9 illustrates a top perspective view of the application of the agent of the container of the kit of FIG. 8 on an on-demand agent dispensing patch of the kit of FIG. 8 coupled to a user according to one embodiment of the present disclosure.

[055] FIG. 10 illustrates a top perspective view of a user compressing an on-demand agent dispensing patch to dispense a volume of agent from an on-demand agent dispensing patch according to one embodiment of the present disclosure.

[056] FIG. 11 illustrates another top perspective view of a user compressing an on-demand agent dispensing patch to dispense a volume of agent from an on-demand agent dispensing patch according to one embodiment of the present disclosure.

[057] FIG. 12 illustrates a top perspective view of an on-demand agent dispensing pocket patch according to one embodiment of the present disclosure. [058] FIG. 13 illustrates another top perspective view of the on-demand agent dispensing pocket patch of FIG. 12 with an adhesive liner layer partially removed according to one embodiment of the present disclosure.

[059] FIG. 14 illustrates a top perspective cross-sectional view of the on-demand agent dispensing pocket patch of FIG. 13 according to one embodiment of the present disclosure.

[060] FIG. 15A illustrates a top perspective view of a user inserting their fingers into the on- demand agent dispensing pocket patch of FIG. 12 according to one embodiment of the present disclosure.

[061] FIG. 15B illustrates a bottom perspective view of the user using the on-demand agent dispensing pocket patch of FIG. 15A to dispense a volume of agent onto their fingers according to one embodiment of the present disclosure.

[062] FIG. 15C illustrates a top perspective view of the user using the on-demand agent dispensing pocket patch of FIG. 15A to dispense a volume of agent onto their fingers according to one embodiment of the present disclosure.

[063] FIG. 16 illustrates a top perspective view of a resealable on-demand agent dispensing pocket patch according to one embodiment of the present disclosure.

DETAILED DESCRIPTION OF THE DRAWINGS

[064] Aspects of the present disclosure and certain examples, features, advantages, and details thereof, are explained more fully below with reference to the non-limiting examples illustrated in the accompanying drawings. Descriptions of well-known components, aspects, materials, chemicals, fabrication mechanisms, processing techniques, uses, etc., are omitted so as not to unnecessarily obscure the relevant details. It should be understood, however, that the detailed description and the specific examples, while indicating aspects of the disclosure, are given by way of illustration only, and are not by way of limitation. Various substitutions, modifications, additions, and/or arrangements, within the spirit and/or scope of the underlying inventive concepts will be apparent to those skilled in the art from this disclosure.

[065] Approximating language, as used herein throughout disclosure, may be applied to modify any quantitative representation that could permissibly vary without resulting in a change in the basic function to which it is related. Accordingly, a value modified by a term or terms, such as "terms "substantially", "approximately", "about", "relatively," or other such similar terms is not limited to the precise value specified, and is used to describe and account for small fluctuations, such as due to variations in processing, from a reference or parameter. Such small fluctuations include a zero fluctuation from the reference or parameter as well. For example, these terms can refer to less than or equal to ±5%, such as less than or equal to ±2%, such as less than or equal to ±1%, such as less than or equal to ±0.5%, such as less than or equal to ±0.2%, such as less than or equal to ±0.1%, such as less than or equal to ±0.05%. In some instances, the approximating language may correspond to the precision of an instrument for measuring the value.

[066] Terminology used herein is for the purpose of describing particular examples only and is not intended to be limiting. As used herein, the singular forms "a", "an" and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. Furthermore, references to "one example" are not intended to be interpreted as excluding the existence of additional examples that also incorporate the recited features. Moreover, unless explicitly stated to the contrary, the terms "comprising" (and any form of "comprise," such as "comprises" and "comprising"), "have" (and any form of "have," such as "has" and "having"), "include" (and any form of "include," such as "includes" and "including"), and "contain" (and any form of "contain," such as "contains" and "containing") are used as open-ended linking verbs. As a result, any examples that "comprises," "has," "includes" or "contains" one or more step or element possesses such one or more step or element, but is not limited to possessing only such one or more step or element. As used herein, the terms "may" and "may be" indicate a possibility of an occurrence within a set of circumstances; a possession of a specified property, characteristic or function; and/or qualify another verb by expressing one or more of an ability, capability, or possibility associated with the qualified verb. Accordingly, usage of "may" and "may be" indicates that a modified term is apparently appropriate, capable, or suitable for an indicated capacity, function, or usage, while taking into account that in some circumstances the modified term may sometimes not be appropriate, capable or suitable. For example, in some circumstances, an event or capacity can be expected, while in other circumstances the event or capacity cannot occur — this distinction is captured by the terms "may" and "may be."

[067] As used herein and unless otherwise indicated, the term "entirety" (and any other form of "entire") means at least a substantial portion, such as at least 95% or at least 99%. The term "entirety" (and any other form of "entire"), as used herein, is thereby not limited to 100%, unless otherwise indicated. [068] The terms "disinfecting," "sanitizing" and "sterilizing" (and the equivalents thereof) are used synonymously herein to refer to the action of trapping, removing, killing, or inhibiting the growth and/or reproduction of a pathogen (i.e., an infectious disease-causing microorganism, such as various viruses, bacteria, fungus, and parasites). Similarly, the terms "disinfectant," "sanitizer," "sterilizer," "antimicrobial" and "antiseptic" (and the equivalents thereof) are used synonymously herein to refer to a substance that disinfects (i.e., that traps, removes, kills, or inhibits the growth and/or reproduction of a pathogen). Such agents may be "topical" in that they disinfect pathogens located on (the outside of) one's skin or the outer/ exterior surface of an object.

[069] The terms "affix," "connect" "contact," "coupled" and/or the like are broadly defined herein to encompass a variety of divergent arrangements and assembly techniques. These arrangements and techniques include, but are not limited to (1) the direct j oining of one component and another component with no intervening components therebetween (i.e., the components are in direct physical contact); and (2) the joining of one component and another component with one or more components therebetween, provided that the one component being "affixed to," "connected to," "contacting" or 'coupled to" the other component is somehow in operative communication with the other component (notwithstanding the presence of one or more additional components therebetween). It is to be understood that some components that are in direct physical contact with one another may or may not be in fluid contact with one another. Moreover, two components that are fluidly/fluidically connected, fluidly/fluidically coupled or in fluid/fluidic communication may or may not be in direct physical contact, and one or more other components may be positioned therebetween.

[070] The present disclosure provides for on-demand agent (e.g., disinfectant) dispensing devices and kits, and related methods utilizing such device and kits, which can be removably affixed to an object (such as a user or a surface of an inanimate object) that provide easy, available access to a supply of the agent over an extended period of time. The devices are configured as a patch that is configured to efficiently provide the agent on an on-demand basis via a step of apply pressure to or compressing the patch in its thickness direction (and potential along a length of the patch, such as a wiping or swiping motion/pathway).

[071] The on-demand agent dispensing patches provide a simple, cost effective way to dispense the agent. The patches are self-contained, and can be used with any agent that can be applied to a “dry” patch, while providing a no spill dispensing solution that does not necessitate pouring or spraying the agent prior to each application or dispensing. In some embodiments, the patch may be configured to be removably affixed to a user, such as to the user's skin or the user's clothing (or any other inanimate object carried or worn by the user). In such a configuration, the on- demand agent dispensing patch provides a wearable device for dispensing the agent. The on- demand agent dispensing wearable devices may be configured to be removably affixed to a contact of a user or object that would benefit from having the agent thereon or thereat, such as on the inside of a user's hand (e.g., on the palm and/or fingers) with the agent being a disinfectant. In this way, the active on-demand agent dispensing wearable patch can be applied over an “active” portion of the user (e.g., a user's elbow, palm, finger, etc.) or object and replace the portion with the outer surface of the patch.

[072] In some embodiments, the on-demand agent dispensing patch may be configured to be wearable such that it is removably affixed to a passive portion of the user's skin (or an object worn/carried by the user) (or on an inanimate object remote from the user) that is spaced from the point/portion of contact of the user, to allow for selective application of the agent via contact of the outer face of the patch via a user pressing on/compressing the patch. For example, a passive on-demand agent dispensing wearable patch may be removably affixed to the back of a user's hand or on a forearm, or on their clothing, and the user may swipe their finger(s)/hand on/over the exposed outer face of the patch to dispense the agent thereon. In such a passive dispensing embodiment, the on-demand agent dispensing wearable patch provides quick and discrete on-demand access to the agent where swi ping/ contacting the device causes the agent to be dispensed on/to the person's point/portion of contact (e.g., their hand(s) or other skin surface).

[073] The on-demand agent dispensing patch disclosed herein can thereby be applied to an active or passive surface portion of a user (or an object) to provide the agent thereon/thereat. In this way, when the agent is a disinfectant, the on-demand dispensing patch can provide an amount/level of disinfectant to a user.

[074] FIGS. 1-6 illustrate an exemplary agent dispensing patch device 10 according to the present disclosure. As noted above, the agent may be any liquid or gelatinous agent that would benefit from, or lend itself to, being available on demand over a period of time, and being dispensed in doses or relatively small volumes. For example, the patch device 10 may be used with a liquid or gelatinous sanitizing/disinfecting agent (i.e., a sanitizer or disinfectant) so that the sanitizing/disinfecting agent is available on demand to a user or an extended period of time, and a volume there can be dispensed for use easily and quickly from the patch device 10 without having to open or otherwise access a container or package of the sanitizing/disinfecting agent.

[075] As shown in FIGS. 1-3, in some embodiments, the on-demand agent dispensing patch device 10 may be a flexible patch configured to contain, and provide on-demand dispensing of, the agent via compression of the patch in a thickness direction thereof.

[076] As shown in FIGS. 1-3, in some embodiments, the on-demand agent dispensing patch device 10 may include at least one reservoir dispenser portion or layer 11 and at least one attachment portion or layer 14. The attachment layer 14 may extend beneath, or underlie, the reservoir dispenser portion 11. The reservoir dispenser portion 11 may thereby extend over the attachment layer 14 in a thickness direction such that a top outer exposed face 20 of the reservoir dispenser portion or layer 11 forms the top outer exposed face of the patch device 10 onto which the agent is applied, and the reservoir dispenser portion 11 may be configured to absorb, so as to contain, the agent. The on-demand agent dispensing patch device 10 may further include at least one backer layer 40 positioned between the attachment layer 14 and the reservoir dispenser portion 11 in the thickness direction, as shown in FIGS. 1-3. The backer layer 40 may be impervious to the agent such that the backer layer 40 prevents the agent from interacting with the attachment layer 14. As explained further below, the attachment layer 14 may comprise an adhesive layer, and the backer layer 40 may thereby prevent the agent from deteriorating or interfering with the adhesive. Further, the backer layer 40 may prevent the agent from penetrating through the patch device 10 in the thickness direction and interacting with the object that the patch device is affixed to, and thereby aid in maintaining or containing the agent in the reservoir dispenser portion 11. The backer layer 40 may also provide a consistent solid surface to apply to couple with the attachment layer 14.

[077] As explained further below, the patch device 10 may be provided to user “dry” such that the reservoir dispenser portion 11 (and the other portions of the patch device 10) is void of the agent absorbed therein. For example, the reservoir dispenser portion 11 (and the other portions of the patch device 10) may be completely void of the agent. In such embodiments, the patch device 10 may form part of a device, system or kit that includes the patch device 10 and a container of the agent that is separate and distinct from the patch device 10, as discussed further below with reference to FIGS. 8 and 9. [078] In some other embodiments, the reservoir dispenser portion 1 1 (and the other portions of the patch device 10) may not have the agent absorbed therein, but the agent may be contained within a manually breakable encapsulation that is provided in, or adjacent to, the reservoir dispenser portion 11 such that a user can manually break the encapsulation to release the agent and allow the reservoir dispenser portion 11 to absorb the agent so that the agent is contained within the reservoir dispenser portion 11. The encapsulation may be a manually breakable shell or envelope. For example, in one exemplary embodiment, the encapsulation may be a foil cover or envelope, a polymer shell or container, or a combination thereof, in whole or in part.

[079] The attachment portion 14 may comprise an attachment side or surface 15 that is configured to affix/couple the patch device 10 to an object (removably or fixedly) (e.g., a user skin or a surface of an inanimate object, as described above and further below). A back side 42 of the backer layer 40 may be coupled to and overlie at least a portion of a front side 18 of the attachment portion 14, as shown in FIGS. 1-3. Similarly, a back side 13/17 of the reservoir dispenser portion 11 may be coupled to and overlie at least a portion of a front side 41 of the backer layer 40, as shown in FIGS. 1-3. The agent reservoir dispenser portion 11 is configured to control a dispense rate (i.e., time release) of the volume of an agent to a user at an exposed outer dispensing surface portion 20 thereof when a user compresses the agent reservoir dispenser portion 11 in thickness direction. In some embodiments, the agent reservoir dispenser portion 11 may be refillable after one or more dispensing by applying a volume of the agent to the exposed outer dispensing surface portion 20 to allow the agent reservoir dispenser portion 11 to absorb the applied volume of the agent.

[080] The patch device 10 (e.g., the attachment portion 14, the backer layer 40, and the agent reservoir dispenser portion 11) may be of any size and any shape. In some embodiments, the patch device 10 may be relatively flat or thin in a thickness direction (e.g., comprise a patch, sheet or like arrangement). In some embodiments, the size and/or shape of the patch device 10 may correspond to a particular surface/object to which it can be removably coupled to. In this way, the patch device 10 may be configured to a particular usage (e.g., shaped and sized to removably attach to a particular object or body portion of a user). The patch device 10 (e.g., the attachment portion 14 and the agent reservoir dispenser portion 11) may be relatively flexible, such as easily manually flexible. [081] The attachment portion 14 may comprise an adhesive layer configured to removably couple the patch to a surface, the adhesive layer defining the inner or back face/attachment side 15 of the patch device 10. As shown in FIGS. 1-3, the attachment side 15 of the attachment portion 14 may define the backside or underside of the patch device 10 when in use, such that the attachment side 15 defines a backside attachment surface of the patch device 10 that is configured to abut or overly another surface when the patch device 10 is coupled thereto. In some embodiments, the attachment portion 14 may include an adhesive on (or that forms) the attachment surface 15 that is configured to removably couple the patch device 10 to a surface.

[082] In some embodiments, the attachment portion 14 may include an adhesive that is configured to removably couple the patch device 10 to an inanimate object and/or a user (e.g., skin or clothing of a user). In some such embodiments, the adhesive may comprise a pressure sensitive adhesive (PSA). In some such embodiments, the attachment portion 14 may be configured to directly removably attach to skin of a user via a biocompatible (and/or medical grade) adhesive, such as a biocompatible PSA, and/or an alcohol resistant adhesive. In some embodiments, the adhesive of the attachment portion 14 may comprise an acrylic adhesive, an epoxy adhesive, a styrene block co-polymer adhesive or a combination thereof. In some such embodiments, the adhesive of the attachment portion 14 may comprise an acrylate, such as methacrylates, epoxy diacrylates (i.e., a vinyl resin) or a combination thereof. In some such embodiments, the adhesive attachment portion 14 may comprise an acrylic-based pressuresensitive adhesive. In some embodiments, the adhesive of the attachment portion 14 may comprise spirit gum (mastic), matte spirit gum, liquid latex, thickened latex, flexible collodion or a combination thereof In some such embodiments, the adhesive may comprise a biodegradable, natural and/or organic adhesive. In some embodiments, the tack, adhesion, shear strength and breathability of the adhesive of the attachment portion 14 may be configured such that the patch device 10 is biocompatible with respect to a user's skin.

[083] In some embodiments, the attachment portion 14 may be formed of an adhesive that covers, surrounds or is otherwise integrated with a scrim layer. The adhesive-scrim construct may form an integrated adhesive-scrim layer that is laid or applied to the backside 42 of the backer layer 40 or the back side 13/17 of the agent reservoir dispenser portion 11, and coupled thereto via the adhesive. [084] In some other embodiments (not shown), the attachment portion 14 may include a mechanical mechanism and/or physical configuration operative to removably attach the device to a surface or object. For example, the attachment portion 14 may include and/or comprise a strap, hook-and4oop (or hook-and-hook) fastener, snap fastener, button, strap, elastic, suction cup/member, zipper, threaded post/aperture, magnet or any other fastener mechanism that is configured to removably couple the patch device 10 to another surface/object. In some embodiments, the attachment portion 14 comprises a clip or flap member that extends from the back face It is noted that the particular design and configuration can of the attachment portion 14 can take on any form with respect to a particular surface/object sufficient to removable couple the patch device 10 to the surface/object.

[085] As shown in FIGS. 2 and 3, in some embodiments, the patch device 10 may include a removable attachment protective film or liner 30 extending over the back side 15 of the attachment layer 14. An inner side 32 of the attachment protective liner 30 may be configured to cover and protect the attachment layer 14 prior to use (or when otherwise not in use), as shown in FIGS. 2 and 3. As also shown in FIGS. 2 and 3, an outer or back side 31 of the protective liner 30 may define the outer back side of the patch device 10 prior to being affixed to a surface (object/person). The protective liner 30 may thereby be configured to be manually removed from the attachment layer 14 (e.g., peeled off) such that the attachment layer 14 remains coupled to the patch device 10 and is effective in coupling the patch device 10 to a surface. In some embodiments, the protective liner 30 may comprise a plastic/polymer, coated paper, metallic/metalized layer (e.g., a foil layer or aluminized material layer) or a combination thereof. In some embodiments, the protective liner 30 may include a tab to aide in manually removing (e.g., peeling) the protective liner 30 from the attachment surface 15 of the adhesive layer 14, as shown in FIGS. 1 and 2.

[086] As noted above, in some embodiments, the patch device 10 may include at least one at least one backer layer or film 40 positioned between the attachment layer 14 and the agent reservoir dispenser portion 11 in the thickness direction, as shown in FIGS. 1-3. The at least one backer layer 40 may be substantially impervious to the agent. The backer layer 40 may support the attachment mechanism 14 (e.g., an adhesive and/or mechanical fastener) (i.e., the attachment mechanism may be coupled to bottom/back side 15 of the backer layer). Further, the agent reservoir dispenser portion 11 may be coupled to and overly (e.g., directly overly) a top/upper side of the backer layer 40, as shown in FIGS. 1-3.

[087] In some embodiments, the backer layer 40 comprises at least one layer of a fabric (woven or non-woven), plastic or latex. For example, the backer layer 40 may comprise a breathable fabric, such as a woven (or non-woven) nylon, polyester or Gore-Tex layer. In some embodiments, the backer layer 40 may be flexible, and may comprise a water absorbable and/or air permeable fabric layer (particularly in embodiments of the patch device 10 for use directly on the skin of a user, as described further below). In some other embodiments, the backer layer 40 may be substantially impervious to the agent and to air. In some embodiments, the backer layer 40 may comprise a solid sheet of material, such as at least one polymer layer, fdm or sheet. In some such embodiments, the backer layer 40 may comprises a polyethylene or polypropylene layer, film or sheet. In some embodiments, the backer layer 40 may comprise at least one polyethylene layer, polypropylene layer, styrene layer, polyetheretherketone layer, acrylic layer, polyvinyl chloride layer, polyurethane layer, Teflon (Polytetrafluoroethylene) layer, syrlyn layer or a combination thereof. In some embodiments, the backer layer 40 may comprise a thickness of .5-3 mm, such as about 1 mm.

[088] In some embodiments, the patch device 10 may comprise a dispenser protective liner, fdm or layer (not shown) extending over the top or outer dispensing surface 20 of the agent reservoir dispenser portion 11. An inner side of the dispenser protective liner may be configured to cover and protect the agent reservoir dispenser portion 11 prior to use (or when otherwise not in use). An outer or top/front side of the protective liner may define the outer front/top side of the patch device 10 prior to use thereof (e.g., prior to dispensing and/or an application of agent applied to the agent reservoir dispenser portion 11). The dispenser protective liner may thereby be configured to cover and protect the dispensing surface portion 20 prior to use (or when otherwise not in use). In some embodiments, the dispenser protective liner may comprise a plastic/polymer or metallic/metalized layer (and potentially an adhesive). Removal of the dispenser protective liner may thereby activate the patch device 10 for use.

[089] In some embodiments, the dispensing surface portion 20 (and/or the outer surface of the protective film liner) may include a visual and/or tactile indication (not shown), or be configured such that a visual and/or tactile indication can be drawn or otherwise formed thereon. For example, the dispensing surface portion 20 (and/or the outer surface of the protective film liner) may include a logo, name, trademark or other visual indication that may enhance the aesthetic look and/or feel of the patch device 10. As another example, the outer surface of the cover or protective fdm liner may be configured as a paper, chalkboard or whiteboard type configuration to allow for personalization of the patch device 10. In some embodiments, the outer surface of the cover or protective liner 0 comprises at least one of a visible light reflective material and an illumination device thereon. In some embodiment the protective liner may include a tab to aide in manually removing (e.g., peeling) the protective liner from the patch device 10/agent reservoir dispenser portion 11.

[090] The agent reservoir dispenser portion 11 may comprise one or more layers and/or more materials. In some embodiments, the agent reservoir dispenser portion 11 may comprise a single layer comprised of one or more materials. In some other embodiments, as discussed above and further below, the agent reservoir dispenser portion 11 may comprise one or more reservoir layers or portions 12 and one or more dispenser layers or portions 16 that is/are separate and distinct from the one or more agent reservoir layers or portions 12.

[091] As shown in FIGS. 1-3, in some embodiments, the agent reservoir dispenser portion 11 of the patch device 10 may include a dispenser layer 16 extending over at least one reservoir layer 12. The reservoir layer 12 is configured to absorb and retain the agent therein, and overlies the attachment layer 14 in the thickness direction. The dispenser layer 16 may overly the reservoir layer 12 in thickness direction, as shown in FIGS. 1-3. The dispenser layer 16 may comprise a plurality of solid portions and an array of a plurality of openings extending through a thickness thereof, and be configured to inhibit evaporation of the agent, and control a flow of the agent from the agent reservoir dispenser portion 11 (and in particular the reservoir layer 12) upon the compression of the patch device 10 in the thickness direction when the agent is contained within the at least one reservoir layer 12. The solid portions of the at least one dispenser layer 16 and portions of the at least one reservoir layer 12 underlying the plurality of openings of the at least one dispenser layer 16 may define outer face 20 of the patch device 10 (when the protective liner is removed, if provided).

[092] The agent reservoir dispenser portion 11 is configured to contain the volume of an agent. For example, an agent may be absorbed into the agent reservoir dispenser portion 11 (e.g., the agent reservoir dispenser portion 11 may comprise an absorbent pad, layer or portion). As another example, the agent reservoir dispenser portion 11 may form at least one cavity, opening or cell that contains an agent. The agent reservoir dispenser portion 11 is also configured to dispense an agent at the dispensing surface portion 20 to a user who compresses the dice 10, such as wiping across a portion of the dispensing surface portion 20. At least a portion of the agent reservoir dispenser portion 11 thereby automatically controls the speed and duration of the release/flow of the agent at/to the outer dispensing surface portion 20 (and thereby to a user on an on-demand basis). For example, the agent reservoir dispenser portion 11 may be configured to draw or otherwise provide a portion of the volume of an agent at or to the dispensing surface portion 20 such that when a user touches or wipes the dispensing surface portion 20, some of an agent transfers to the user.

[093] In some embodiments, the reservoir and dispensing functions or processes of the agent reservoir dispenser portion 11 may be accomplished by a common layer or portion of the agent reservoir dispenser portion 11. In some other embodiments, the reservoir and dispensing functions or processes of the reservoir and dispensing functions or processes may be accomplished by differing layers or portions of the agent reservoir dispenser portion 11.

[094] As discussed above and shown in FIGS. 1-3, in some embodiments, the agent reservoir dispenser portion 11 may comprise at least one reservoir layer or portion 12 that is configured to absorb and retain the agent therein. In some embodiments, the at least one reservoir layer or portion 12 may comprise a nonwoven absorbent fabric layer. For example, in one embodiment, the at least one reservoir layer 12 may be formed of a fabric layer of non-woven polymer fibers, such as non-woven polyethylene and/or polypropylene fibers. In some embodiments, the at least one reservoir layer or portion 12 may comprise a natural or synthetic non-woven fabric layer. The at least one reservoir layer 12 may comprise one or more layers of polymer fibers, cotton fibers, silicone fibers, hydrogel or a combination thereof. In some embodiments, the at least one reservoir layer or portion 12 may comprise one or more layers of a fabric, Gore-Tex, gauze, an absorbing gel, a polymer, paper, a foam or a combination thereof.

[095] In some embodiments, the at least one reservoir layer or portion 12 may be formed of a (woven or non-woven) cloth or fabric (e g., a cotton, nylon, polyester or the like layer/portion), Gore-Tex, gauze, absorbing gel (e.g., a hydrogel), flashspun high-density polyethylene (e g , Tyvek), porous/filter paper, plastic film, foam, hydrocolloid, alginate, polysaccharide pastes, granules and/or beads, or a combination thereof. For example, is some embodiments the reservoir portion 12 may comprise one or more layers of cotton, polyester, silicone, polyurethane, polyamide, polyethylene, hydrogel or a combination thereof. In some such embodiments, the reservoir portion 12 may include a cotton fabric layer or portion, a nylon fabric layer or portion, a polyester fabric layer or portion, a flashspun high-density polyethylene fiber layer or portion, a hydrogel layer or portion, a flexible polyamide net coated with silicone layer or portion, a hydrogel layer or portion formed of hydrophilic polymers, or a combination thereof.

[096] In some embodiments, the at least one reservoir layer or portion 12 may be configured to absorb and retain within the range of about 2 grams and about 50 grams of the agent, and/or have a detached agent capacity within the range of about 1,000 g/mm2 and about 2,500 g/mm2. In some embodiments, the at least one reservoir layer 12 comprises an agent absorbency rate of at least 5 g/sec for at least the first 5 seconds of water contact. The at least one reservoir layer or portion 12 can be configured such that when the agent is contained/absorbed therein, a compressive force acting in the thickness direction and applied to the outer dispensing surface 20 of the patch device 10 of at least 1 gram/mm2 causes the agent to flow through from the at least one reservoir layer or portion 12 and onto the outer dispensing surface 20 (potentially trough apertures in an outer dispenser layer 16, as discussed further below) and/or an onto an object at the outer dispensing surface 20.

[097] As discussed above and shown in FIGS. 1-3, in some embodiments, the agent reservoir dispenser portion 11 may comprise at least one dispenser layer or portion 16 comprising a plurality of solid portions and an array of a plurality of openings or apertures extending through a thickness thereof, the at least one dispenser layer 16 configured to inhibit evaporation of the agent, and control a flow of the agent from the at least one reservoir layer 12, upon the compression of the patch device 10 in the thickness direction when the agent is contained within the at least one reservoir layer.

[098] The at least one dispenser layer 12 may comprise at least one perforated or micro porous film or layer. In some embodiments, the at least one dispenser layer 12 comprises a sheet or layer of material that is impervious to the agent and/or impervious to air. In some embodiments, the at least one dispenser layer 12 comprises a polymer layer. In some embodiments, the at least one dispenser layer 12 comprises at least one polyethylene layer, polypropylene layer, styrene layer, polyetheretherketone layer, acrylic layer, polyvinyl chloride layer, polyurethane layer, Teflon (Polytetrafluoroethylene) layer, syrlyn layer or a combination thereof. [099] In some embodiments, the solid portions of the at least one dispenser layer 12 may comprise within the range of about 10% and about 65% of the total area of the outer dispensing face/side 20 of the patch device 10. In some embodiments, the plurality of openings of the at least one dispenser layer 12 comprise a total area within the range of about 50 mm2 and about 300 mm2 at the outer dispensing face/side 20 of the patch device 10. In some embodiments, each of the plurality of openings of the at least one dispenser layer 12 comprise a total area within the range of about .05 mm2 and about .3 mm2 at the outer dispensing face/side 20 of the patch device 10.

[0100] At least the dispensing portion 12 of the agent reservoir dispenser portion 11 may be configured to control the amount and/or rate at which an agent moves or is drawn therethrough (e.g., via capillary action) and to the dispensing surface portion 20. The agent reservoir dispenser portion 11 is thereby configured to meter/control the release or dispensing of an agent to/from/at the dispensing surface portion 20. For example, at least one of the pore/perforation size, pore/perforation count/number, density and thickness of the at least one dispenser layer 12, and capillary action of the agent reservoir dispenser portion 11, may be configured to control the amount and/or rate at which an agent moves or is drawn to and through the at least one reservoir layer/portion 12 and the at least one dispenser layer 16 to the dispensing surface portion 20. The agent reservoir dispenser portion 11 may be configured such that a particular dosage of an agent flows through the agent reservoir dispenser portion 11 and the dispensing surface portion 20 when a certain pressure (e.g., a certain magnitude, area, direction, etc.) is applied thereto by a user such that the particular dosage of an agent is transferred to the dispensing surface portion 20 (and thus a user or surface applying the compression/pressure) thereby.

[0101] In some embodiments, the patch device 10 (formed of the agent reservoir dispenser portion 11 (e g., comprising the at least one reservoir layer/portion 12 and the at least one dispenser layer/portion 16), the at least one backer layer/portion 40 and at least one attachment layer/portion 14) being saturated with a liquid or gelatinous agent, such as those disclosed herein, is configured such that the agent is available/dispensable at the dispensing surface portion 20 via touching or swiping of the dispensing surface portion 20 by a user for at least 2 hours, at least 3 hours, at least 4 hours, at least 5 hour or at least 6 hours after the dispensing surface portion 20 is initially exposed to air. In some embodiments, the patch device 10 is configured such that when a liquid or gelatinous agent, such as those disclosed herein, is absorbed within the at least one reservoir layer 12, the patch device 10 is configured such that no more than 5 grams of the agent evaporates over 1.5 hours in an ambient environment of non -moving/ stagnant air at 20 degrees Celsius.

[0102] The agent may be any biocompatible disinfectant (i.e., safe and effective for use with humans, such as on human skin), such as any topical disinfectant effective in killing and/or preventing reproduction of disease causing pathogens (such as viruses and bacteria, for example) when an agent and the pathogens physically interact. An agent may be effective on disinfecting a person's skin and in addition to the surface of an inanimate object (such as a surface comprising plastic, metal, glass, paper, carboard, etc.). For example, an agent may comprise an alcohol sanitizer and/or a non-alcohol sanitizer. In some embodiments, the agent may comprise a disinfectant comprising ethyl, isopropyl, ethanol (ethyl alcohol), triclosan, triclocarban, benzalkonium chloride, benzethonium chloride or a combination thereof. In some embodiments, the agent may comprise a disinfectant comprising ethanol (ethyl alcohol). In some embodiments, the agent may comprise a dynamic viscosity within the range of about 4 (Pa s)(m2/s) and about 15 (Pa s)(m2/s) at 20 degrees Celsius. In some embodiments, the agent may comprise a medicant or vitamin, insecticide, fragrance, food product, cleaning product, paint and/or oil.

[0103] In some embodiments, an agent comprises ethyl, isopropyl, ethanol (ethyl alcohol), triclosan, triclocarban, benzalkonium chloride, benzethonium chloride or a combination thereof. In some embodiments, an agent comprises 1,2-hexanediol, ammonium bicarbonate, ammonium carbonate, benzalkonium chloride, benzalkonium chloride, chlorine dioxide, citric acid, dodecylbenzenesulfonic acid, ethanol, ethyl, glutaraldehyde, glycolic acid, hydrochloric acid, hypochlorous acid, isopropyl, isopropanol, lactic acid, L-lactic acid, octanoic acid, peroxyacetic acid, peroxyoctanoic acid, phenolic, potassium peroxymonosulfate, quaternary ammonium, silver, silver ion, sodium carbonate, sodium carbonate peroxyhydrate, sodium chloride, sodium chlorite, sodium dichloroisocyanurate, sodium dichloroisocyanurate dihydrate, sodium dichloro- S-triazinetrione, sodium hypochlorite, thymol, triethylene glycol, triclosan, triclocarban, alcohol (e.g., at least 60% by volume), aloe gel, vinegar, an essential oil, aromatherapy compound, or a combination thereof, In some embodiments, an agent may comprise at least one essential oil, such as geranium, lavender, sweet marjoram, neroli, palmarosa, peppermint, petitgrain, rose, tea tree, thyme, linalool oil or a combination thereof. In some embodiments, an agent may be in liquid or gel form. In some embodiments, an agent may comprise a solution and/or a suspension, and may include at least solid disinfectants.

[0104] It is also specifically disclosed herein that although embodiments of the on-demand dispensing devices (and related methods) of the present disclosure are described with respect to containing and dispensing a disinfectant (i.e., on-demand disinfectant dispensing devices), the devices may equally be employed to dispense any other solid, liquid or gel agent. For example, the devices may contain and be configured to dispense any pleasant or foul odorous and/or tasteful material (e.g., perfume, attractant/detractant-repellant (e.g., bug or insect repellant, etc.). As another example, the devices may contain and be configured to dispense a skin lotion (e.g., moisturizer, sunscreen, etc.), antiperspirant/deodorant, medication/medicine, lubricant, frictionenhancing material (e.g., a sticky or gritty material), any other biocompatible material, biohazard material or a combination thereof. In some such embodiments, the medication/medicine may be a medicant, a vitamin (vitamin C, B12, etc.) or supplement (e.g., caffeine, nicotine, etc.), a cannabinoid (e.g., cannabidiol (CBD)), delta-9-tetrahydrocannabinol (THC) or a food product (e.g., sugar, candy, etc.). As a further example, the devices may contain and be configured to dispense a paint. As another example, the devices may contain and be configured to dispense a cleaning product. As another example, the devices may contain and be configured to dispense a food product or foodstuff.

[0105] The layers or portions of the patch device 10 may be coupled together via any means, such as any mechanical and/or chemical mode or method. In some embodiments, the layers or portions of the patch device 10 are adhered to each other. In some embodiments, the layers or portions of the patch device 10 are bonded to each other. In some such embodiments, the layers or portions of the patch device 10 are bonded to each other via the materials making up the layers or portions. For example, in some embodiments, at least some of the adjacent layers or portions of the patch device 10 may be bonded to each other via the layers or portions being heated above their melting or softening points and becoming bonded together. In some such embodiments, the at least one reservoir layer 12 and the at least one dispenser layer 16, and/or the at least one reservoir layer 12 and the at least one backer layer 40, may be heat, radio-frequency and/or ultrasonic welded together. In some embodiments, if the at least one reservoir layer 12, the at least one dispenser layer 16 and/or the at least one backer layer 40 are formed of more than one overlapping layers, such layers may be bonded together. [0106] As shown in FIGS. 4-6, in some embodiments, the patch device 10 may be bonded or adhered together such that an outer peripheral portion 60 is compressed together as compared to an interior or central portion of the patch device 10. The outer peripheral portion 60 may thereby define a total/maximum thickness T1 that is less than that of the interior or central portion of the patch device 10. In some embodiments, the outer peripheral portion 60 may be formed via at least sone of the the layers/portions of the patch device 10 being compressed and bonded together, such as via heat, radio-frequency and/or ultrasonic welded together.

[0107] In some embodiments, the patch device 10 may define a total/maximum thickness within the range of about .05 mm and about 3 mm. In some embodiments, the outer peripheral portion 60 may thereby define a total/maximum thickness T1 that less than 75%, such as about 50%, that of the interior or central portion of the patch device 10.

[0108] The periphery of the patch device 10 may define any shape and size. For example, as shown in FIGS. 4 and 5, in one exemplary embodiment the patch device 10 may define an oval or oblong shape such that a length of the patch device 10 is greater than a width of the patch device 10 (such as a width of within the range of 1 inch to 4 inches, and a length of 1.5 to 10 inches). In some other exemplary embodiments (not shown), the patch device 10 may define a circular shape (e.g., with a diameter within the range of 1 inch to 4 inches, or within the range of 1 inch to 2.5 inches).

[0109] As shown in FIGS, a kit, system or device according to the present disclosure may include one patch device 10, or may include a plurality of patch devices 10 as shown in FIGS. 7 and 8. Further, as noted above, the one or more patch devices 10 may or may not include an agent incorporated into the patch device 10. For example, the one or more patch devices 10 may be entirely void of an agent to be dispensed, or at least void of an agent being absorbed in the reservoir dispenser portion 11 (e.g., absorbed in the at least one reservoir layer 12).

[0110] As shown in FIG. 7, in some embodiments, a kit, system or device a kit, system or device according to the present disclosure may include a plurality of the patch devices 10 provided or coupled to a substrate or carrier material 62. In some embodiments, the plurality of the patch devices 10 may be coupled to the substrate or carrier material 62 via the attachment portion 14 thereof (e.g., an adhesive layer). In some other embodiments, the plurality of the patch devices 10 may be coupled to the substrate or carrier material 62 via an additional adhesive, member or mechanism. [0111] As shown in FIG. 8, in some embodiments a kit, system or device according to the present disclosure may include one or more of the patch devices 10 (e.g., a plurality of the patch devices 10) and a container 66 of an agent to be dispensed by the one or more patch devices 10. For example, as disclosed above, the agent may be a disinfectant/sanitizer. In such embodiments, the one or more patch devices 10 can be provided void of the agent, and the agent can be applied to a patch device 10 when an on-demand dispensing supply of the agent is desired. For example, as shown in FIG. 9, a “dry” patch device 10 devoid of the agent may be attached or coupled to a surface, such as adhered to a user, and the container 66 of the agent may be utilized by the user to apply a volume of the agent to the dispensing surface 20 so that the agent is absorbed into the reservoir dispenser portion 11 (e.g., absorbed into the at least one reservoir layer 12).

[0112] The container 66 can thereby be separate and distinct from the one or more patch devices 10, and the one or more patch devices 10 can be provided and stored prior to use with the agent reservoir dispenser portion 11 (and the other portions) of the one or more patch devices 10 being void of the agent, such as the agent not being absorbed in the at least one reservoir layer 12 thereof.

[0113] In an alternative embodiment, one or more containers 66 of an agent may be integrated into each of the one or more patch devices 10 such that the agent is contained and not absorbed in the at least one reservoir layer 12, but configured such that release of the agent form the container causes the agent to flow into/be absorbed by the agent reservoir dispenser portion 11 (e.g., the at least one reservoir layer 12). For example, the one or more containers 66 of an agent may be embedded within, or positioned adjacent or near, the agent reservoir dispenser portion 11 (e.g., the at least one reservoir layer 12) of a patch device 10. As also described above, in such embodiments, the one or more containers 66 may be manually breakable or openable so that the agent can be selectively manually released from the one or more containers 66.

[0114] After a volume of the agent is provided on the patch device 10 via the container 66, and the agent (e.g., at least a majority thereof) is absorbed into the agent reservoir dispenser portion 11 (e.g., into the at least one reservoir layer 12), a user may compress the patch device 10 in the thickness direction to force a certain dose or volume of the agent from the agent reservoir dispenser portion 11 and to the user at the dispensing surface 20. For example, as shown in FIG. 10, a user may compress and “crunch” a device patch 10 via a hand that the patch device 10 is coupled to. It is noted such a motion/method could also break an encapsulated agent contained within/on the patch device 10 to release the agent into the agent reservoir dispenser portion 11, and also dispense the agent.

[0115] As another example, as shown in FIG. 11, a user may swipe the dispensing surface 20 to compress a length of the patch device 10 in the thickness direction to force a certain dose or volume of the agent from the agent reservoir dispenser portion 11 and to the user at the dispensing surface 20. In such a method, the patch device 10 may be coupled to a surface (e.g., a portion of a user, such as a user’s forearm, as an example) that is remote from a user’s hand, and the user may use the hand to swipe the patch device 10 and dispense a volume of the agent from the patch device 10.

[0116] In some embodiments, the patch device 10 may be configured such that it can be coupled to a user on a passive piece of clothing (e g., hat, shirt, coat, pant, belt, shoe, scarf, glove, sock, etc.) or another inanimate object (sweatband, kinesiology/muscle tape, heat/cool pads, helmet, protective pad/brace/splint/cast, headphones, luggage, personal accessories, luggage, wallet, hand bag/purse, athletic equipment, etc.) that is configured to couple to (i.e., be worn or carried by) the user. The patch device 10 may thereby be removably coupled to a passive portion of the user that is spaced from the point/portion of contact of the user that the user wishes to apply the agent to via touching of the dispensing surface portion 20. As noted above, the attachment portion 14 may include and adhesive or mechanical connection mechanism that is configured to attach to a specific or general surface, such as to the clothing or another inanimate object on/coupled to the user. In use, the user can thereby removably couple the patch device 10 to their clothing or another inanimate object on/coupled to the user on a passive portion of the user (such as but not limited to over the user's forearm, upper arm, chest, waist or thigh), and touch or wipe the dispensing surface portion 20 with one or more of their hands when the user desires to apply the agent thereto (e.g., disinfect) their one or more of their hands (or another body portion or inanimate object touched by the user's one or more hand). When the user desires, the patch device 10 can be removed from the clothing or another inanimate object on/coupled to the user (preferably without damaging the surface outer surface thereof).

[0117] As also discussed above, in some embodiments, the attachment portion 12 (and potentially the reservoir dispenser portion 11) may be configured such that the patch device 10 is worn by a user directly on their skin. The attachment portion 14 may thereby be configured to be biocompatible with a person's passive skin, and the patch device 10 may be breathable or otherwise resistant to causing the user to sweat beneath the device 10. For example, the patch device 10 may be configured to have an “invisible” feel when attached to a user's skin. The patch device 10 may thereby be removably coupled to a user’s skin. In use, the user can thereby removably couple the patch device 10 directly to their skin (such as but not limited to on the user's hand, forearm, upper arm or thigh), and touch or wipe the dispensing surface portion 20 with one or more of their hands when the user desires to apply the agent (e.g., a disinfectant) to their one or more of their hands (or another body portion or inanimate object touched by the user's one or more hand). When the user desires, the patch device 10 can be removed from the skin of the user (preferably without hurting, irritating or otherwise damaging the skin).

[0118] In some exemplary embodiments, the patch device 10 may be configured (e.g., shaped and sized) to removably couple to and extend over (e g., cover) the palm and/or at least a portion of at least one finger of a hand of a user. As another example, in some embodiments, the patch device 10 may be configured (e.g., shaped and sized) to removably couple to and extend over (e.g., cover) just a portion of the palm of a hand of a user, as shown in FIG. 10. In some other exemplary embodiments, the patch device 10 may be configured (e.g., shaped and sized) to removably couple to and extend over (e.g., cover) at least a portion of an interior side of a finger of a hand of a user. As another example, in some embodiments, the patch device 10 may be configured (e.g., shaped and sized) to removably couple to and extend over (e.g., cover) just a portion of the forearm of an arm of a user, as shown in FIGS. 9 and 11, for example. In some other exemplary embodiments, the patch device 10 may be configured (e.g., shaped and sized) to removably couple to and extend over (e.g., cover) at least a portion of an elbow of an arm of a user.

[0119] In yet another embodiment, the patch device 10, such as at least the attachment portion 14, may be configured to attach to an inanimate object (not shown) that is not worn or carried by a user. For example, the attachment portion 14 may be configured to removably (or fixedly) attach to a handle, knob, switch, arm rest, seat, steering wheel, transmission/shift lever, athletic equipment, medical equipment, office equipment, culinary equipment, military/defense equipment, packaging (e.g., a shipping or product packaging), furniture, pet product, or any other item or surface that is communal (i.e., likely to be touched by more than one person) or that is positioned within/near a communal space area, surface or item. [0120] In some embodiments, the patch device 10 may be configured such that the appearance of a portion of the patch device 10, such as the dispensing surface portion 20, changes as the volume of an agent within the reservoir dispenser portion 11. In this way, the patch device 10 may automatically visually and/or tactically indicate the particular volume of an agent within the reservoir dispenser portion 11, and thereby available to the user via the dispensing surface portion 20, at any particular time. It is noted that the patch device 10 may be configured to variably change colors as the volume of an agent changes, or may only change colors once when the level of an agent is at least substantially depleted and/or the level available to a user is inadequate (to disinfect, for example). For example, the reservoir dispenser portion 11 and/or an agent may be configured to change color with changes in the temperature, pH and/or dryness/wetness (e.g., liquid vs. solid form) thereof. As the volume of an agent within the reservoir dispenser portion 11 decreases (such as from being dispensed via the dispensing surface portion 20, to a user and/or evaporating (or otherwise changing states), the temperature, pH and/or dryness/wetness (e.g., liquid/solid state) of the reservoir dispenser portion 11 and/or an agent may change and cause a color change, such as with respect to a material/component/chemical/additive of or within the reservoir dispenser portion 11 and/or an agent. In some embodiment, the reservoir dispenser portion 11 and/or an agent may be configured to change color with time, independently of the actual volume of an agent. For example, the reservoir dispenser portion 11 and/or an agent may include a pigment, ink dye or the like that degrades or absorbs over time such that the color thereof changes over time. In this way, the color of the patch device 10 can indicate to a user how long the patch device 10 has been in use, and thereby an indication of the potential state of the volume of an agent (e.g., an agent may evaporate over time).

[0121] As another example, the patch device 10 may be configured such that the size, shape, surface texture and/or other physical dimension/aspect of the patch device 10 changes as the volume of an agent within the reservoir dispenser portion 11 decreases to provide a tactile indication of the level thereof. For example, the dispensing surface portion 20 may include raised bumps or the like that flatten/ shorten as the volume of an agent within the reservoir dispenser portion 11 decreases.

[0122] Another exemplary on-demand dispensing device 110 that is configured as a pocket patch device 110 is shown in FIGS. 12-16. The device 110 of FIGS. 12- 16is substantially similar to the patch device 10 described above with respect to FIGS. 1-1 1, and therefore like reference numerals preceded with “1” are used to indicate like components, aspects, layers, portions, functions, processes and the like, and the description above directed to thereto equally applies, and is not repeated for brevity and clarity purposes.

[0123] As shown in FIGS. 12-15, the device 110 comprises a flexible agent-impervious pocket 170 comprising a front portion or face 174, a back portion or face 176, a bottom portion 175, a top portion 176, lateral side portions 177 that form an agent-impervious interior cavity or pocket 175 between inner sides of the front and back faces, the lateral side portions 177 and above the bottom portion 175. The interior cavity 175 is thereby closed at the bottom portion 175 and the lateral side portions 177 (and at the front and back sides 174, 172), as shown in FIGS. 12-15. As also shown in FIGS. 12-15 the agent-impervious pocket 170 is open or openable at a top or upper end portion 176 on the pocket 170. The open top end 176 thereby provides access into the interior cavity 175.

[0124] The pocket 170 may be impervious to an agent such that the agent (e.g., a liquid or gelatinous agent) contained within the interior cavity 175 (as explained further below) is unable to flow or otherwise pass through the front portion 174, the back portion 176, the bottom portion 175 and the lateral side portions 177. In some embodiments, the pocket 170 may be impervious to air such that air is unable to pass into the interior cavity 175 (or pass therefrom) through the front portion 174, the back portion 176, the bottom portion 175 and the lateral side portions 177.

[0125] The pocket 170 may be formed from or comprise the same or similar materials as the backer layer 40 and/or dispenser layer 16 as disclosed herein. For example, in some embodiments, the pocket 170 (e.g., the front portion 174, the back portion 176, the bottom portion 175 and the lateral side portions 177) may be formed a solid sheet of material. In some embodiments, the pocket 170 may be formed of or comprise a polymer layer or film. In some embodiments, the pocket 170 may be formed of or comprise at least one polyethylene layer, polypropylene layer, styrene layer, polyetheretherketone layer, acrylic layer, polyvinyl chloride layer, polyurethane layer, Teflon (Polytetrafluoroethylene) layer, syrlyn layer or a combination thereof.

[0126] In some embodiments, the front portion or face 174 and/or the back portion or face 176 may be the backer layer 40 of the device 10 described herein. In such embodiments, an additional backer layer 40, or the two backer layers 40, 40, may be coupled together (e g., bonded) at their lateral sides and bottom end portions to form the flexible agent-impervious pocket 170.

[0127] As shown in FIGS. 12-15, at least one reservoir dispenser portion or layer 111 may be coupled within the interior cavity 175 such that the dispensing surface portion 120 is exposed to the interior of the interior cavity 175. For example, a reservoir dispenser portion 111 may be coupled to an inner side of the front portion 174 within the interior cavity 175, a reservoir dispenser portion 111 may be coupled to an inner side of the back portion 172 within the interior cavity 175, or a first reservoir dispenser portion 111 may be coupled to the inner side of the front portion 174 within the interior cavity 175 and a second reservoir dispenser portion 111 may be coupled to the inner side of the back portion 172 within the interior cavity 175. It is noted that the reservoir dispenser portion 111 may be coupled to the back portion 172 and/or the front portion 174 via an adhesive, bonded thereto and/or a mechanical attachment. In some embodiments, a backer layer may be positioned/coupled between the reservoir dispenser portion 111 and a respective one of the back portion 172 or the front portion 174.

[0128] As discussed in detail above, the reservoir dispenser layer I l l is configured to absorb and retain a liquid or gelatinous agent therein, and control a flow of the agent therefrom upon/via compression of the reservoir dispenser layer 111 retained/ab sorbed therein. As also discussed above, the reservoir dispenser portion 111 may initially be void of the agent, or at least void of the agent being absorbed therein, and applied from a separate and distinct container. As another example, the reservoir dispenser portion 111 may not contain an agent absorbed therein, but the pocket patch device 110 may contain an encapsulated or container of the agent that can be manually broken or otherwise opened to allow the agent to flow to and be absorbed by the reservoir dispenser portion.

[0129] The pocket patch device 110 may be configured such that the interior cavity 175 is sized and shaped to allow at least one finger of a user to extend into the interior cavity 175 and engage the dispensing surface portion 120 to compress the reservoir dispenser layer 111 and dispense agent therefrom and onto the user, as shown in FIGS 15A-C. As also shown in FIGS 15A-C, in some embodiments the pocket patch device 110 may be configured such that the interior cavity 175 is sized and shaped to allow multiple fingers, or whole hand, of a user to extend into the interior cavity 175 and engage the dispensing surface portion 120 to compress the reservoir dispenser layer 111 and dispense agent therefrom and onto the user’s fingers/hand. [0130] As shown in FIGS. 13 and 14, the outer side of the pocket 170 may include the attachment layer or portion 114 (and potentially a liner layer protecting/covering the attachment layer or portion 114) configured to removably couple the pocket patch device 110 to a surface, as described above. In some embodiments, the outer side or face of the back portion 172 may include the attachment portion 114 coupled thereto, as shown in FIGS. 13 and 14. In some embodiments, the outer side or face of the front portion 174 may include the attachment portion 114 coupled. In some embodiments, the outer side or face of the back portion 172 may include a first attachment portion 114 coupled thereto, and the outer side or face of the front portion 174 may include a second attachment portion 114 coupled thereto. As described above, the attachment portion(s) 114 may be an adhesive or a mechanical mechanism configured to removably couple the pocket patch device 110 to a surface, for example.

[0131] In some embodiments, the top or upper end portion 176 of the pocket 170 may initially be closed (and potentially sealed), and be configured to be opened or unsealed. For example, as shown in FIG. 16, the top end portion 176 of the pocket 170 may include or comprise a closed construct. The closed construct may be sealed, and be configured to be openable and closable, or just openable, such that the top end portion 176 becomes open to the interior cavity 175.

[0132] As shown in FIG. 16, in some embodiments, the closed construct 182 may include a openable and closable closure 184. For example, the closure 184 may be a peel-and-stick closure or a zipper closure (single or double, for example) that includes mating hooked channels or a mating hooked channel and hooked male member. The closure 184 may allow for selective manual opening and closing/sealing of the top end portion 176 for selective access to the interior cavity 175. The closure 184 may prevent an agent and/or air from flowing through the top end portion 176 to/from the interior cavity 175.

[0133] In some embodiments, as shown in FIG. 16, the top end portion 176 of the pocket 170 may have a seal 180 at an end portion thereof that seals off the top end portion 176 and access to/from the interior cavity 175. As also shown in FIG. 16, in some such embodiments the top end portion 176 may further comprise an unsealed portion 182 positioned between the seal 180 and the interior cavity 175. The unsealed portion 182 may be configured to be cut, broken, tom or otherwise disconnected such that the seal can be selectively separated from the pocket 170 to open the top end portion 176 and provide access to/from the interior cavity 175. It is noted that the closure 184, the seal 180 and the unsealed portion 182 may all be provided at the top end portion 176.

[0134] It is to be understood that the above description is intended to be illustrative, and not restrictive. For example, the above-described examples (and/or aspects thereof) may be used in combination with each other. In addition, many modifications may be made to adapt a particular situation or material to the teachings of the various examples without departing from their scope. While dimensions and types of materials may be described herein, they are intended to define parameters of some of the various examples, and they are by no means limiting to all examples and are merely exemplary. Many other examples will be apparent to those of skill in the art upon reviewing the above description. The scope of the various examples should, therefore, be determined with reference to the claims included herein, along with the full scope of equivalents to which such claims are entitled.

[0135] As used herein, the terms "including" and "in which" are used as the plain-English equivalents of the respective terms "comprising" and "wherein." Moreover, as used herein, the terms "first," "second," and "third," etc. are used merely as reference labels, and are not intended to impose numerical, structural or other requirements. Forms of term "based on" herein encompass relationships where an element is partially based on as well as relationships where an element is entirely based on. Forms of the term "defined" encompass relationships where an element is partially defined as well as relationships where an element is entirely defined. Further, the limitations of the claims included herein are not written in means-plus-function format and are not intended to be interpreted based on 35 U.S.C. § 112, sixth paragraph, unless and until such claim limitations expressly use the phrase "means for" followed by a statement of function cavity of further structure. It is to be understood that not necessarily all such objects or advantages described above may be achieved in accordance with any particular example. Thus, for example, those skilled in the art will recognize that the systems and methods described herein may be embodied or carried out in a manner that achieves or optimizes one advantage or group of advantages as taught herein without necessarily achieving other objects or advantages as may be taught or suggested herein.

[0136] While the disclosure has been described in detail in connection with only a limited number of examples, it should be readily understood that the disclosure is not limited to such disclosed examples. Rather, this disclosure can be modified to incorporate any number of variations, alterations, substitutions or equivalent arrangements not heretofore described, but which are commensurate with the spirit and scope of the disclosure. Additionally, while various examples have been described, it is to be understood that aspects of the disclosure may include only one example or some of the described examples. Also, while some disclosures are described as having a certain number of elements, it will be understood that the examples can be practiced with less than or greater than the certain number of elements.

[0137] It should be appreciated that all combinations of the foregoing concepts and additional concepts discussed in greater detail below (provided such concepts are not mutually inconsistent) are contemplated as being part of the inventive subject matter disclosed herein. In particular, all combinations of claimed subject matter appearing at the end of this disclosure are contemplated as being part of the inventive subject matter disclosed herein.