Title:
ADAMANTANE DERIVATIVE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/131097
Kind Code:
A1
Abstract:
Provided is a pharmaceutical composition for the treatment or prevention of a cognitive disease or disorder, the composition comprising a compound represented by formula (1), an enantiomer thereof or diasteriomer thereof, or a pharmaceutically acceptable salt thereof.
Inventors:
MORIGUCHI SHIGEKI (JP)
FUKUNAGA KOJI (JP)
IWABUCHI YOSHIHARU (JP)
FUKUNAGA KOJI (JP)
IWABUCHI YOSHIHARU (JP)
Application Number:
PCT/JP2017/002760
Publication Date:
August 03, 2017
Filing Date:
January 26, 2017
Export Citation:
Assignee:
UNIV TOHOKU (JP)
International Classes:
C07C233/47; A61K31/198; A61K31/221; A61K31/223; A61K31/655; A61P3/10; A61P25/00; A61P25/16; A61P25/18; A61P25/28; A61P43/00; C07C229/28; C07C247/14; C07D213/40
Domestic Patent References:
| WO2015087262A1 | 2015-06-18 | |||
| WO2011142246A1 | 2011-11-17 | |||
| WO2009020140A1 | 2009-02-12 | |||
| WO2010043953A2 | 2010-04-22 |
Foreign References:
| CN104001150A | 2014-08-27 | |||
| JP2011529057A | 2011-12-01 | |||
| JP2010522203A | 2010-07-01 | |||
| JP2009508956A | 2009-03-05 | |||
| JP2011529057A | 2011-12-01 | |||
| JP2010522203A | 2010-07-01 | |||
| JP2009508956A | 2009-03-05 |
Other References:
FOLIA PHARMACOLOGICA JAPONICA, vol. 126, 2005, pages 311 - 316
FOLIA PHARMACOLOGICA JAPONICA, vol. 124, 2004, pages 145 - 151
J. AM. CHEM. SOC., vol. 136, 2014, pages 17591 - 17600
FUKUNAGA K ET AL., J. BIOL. CHEM., vol. 267, 1992, pages 22527 - 22533
STURCHLER-PIERRAT ET AL., PROC. NATL. ACAD. SCI. U.S.A., vol. 94, 1997, pages 13287 - 13292
FUKUNAGA ET AL., J. BIOL. CHEM., vol. 267, 1992, pages 22527 - 22533
KASAHARA ET AL., J. BIOL. CHEM., vol. 276, 2001, pages 24044 - 24050
MIKI T ET AL., PROC. NATL. ACAD. SCI. U.S.A., vol. 95, 1998, pages 10402 - 10406
MIKI T ET AL., NATURE MEDICINE, vol. 8, 2002, pages 466 - 472
TAKAO K ET AL., PLOS ONE, vol. 5, 2010, pages e9460
KASAHARA J ET AL., J. BIOL. CHEM., vol. 276, 2001, pages 24044 - 50
See also references of EP 3409659A4
FOLIA PHARMACOLOGICA JAPONICA, vol. 124, 2004, pages 145 - 151
J. AM. CHEM. SOC., vol. 136, 2014, pages 17591 - 17600
FUKUNAGA K ET AL., J. BIOL. CHEM., vol. 267, 1992, pages 22527 - 22533
STURCHLER-PIERRAT ET AL., PROC. NATL. ACAD. SCI. U.S.A., vol. 94, 1997, pages 13287 - 13292
FUKUNAGA ET AL., J. BIOL. CHEM., vol. 267, 1992, pages 22527 - 22533
KASAHARA ET AL., J. BIOL. CHEM., vol. 276, 2001, pages 24044 - 24050
MIKI T ET AL., PROC. NATL. ACAD. SCI. U.S.A., vol. 95, 1998, pages 10402 - 10406
MIKI T ET AL., NATURE MEDICINE, vol. 8, 2002, pages 466 - 472
TAKAO K ET AL., PLOS ONE, vol. 5, 2010, pages e9460
KASAHARA J ET AL., J. BIOL. CHEM., vol. 276, 2001, pages 24044 - 50
See also references of EP 3409659A4
Attorney, Agent or Firm:
ONO, Shinjiro et al. (JP)
Download PDF: